22 completed, 4 unknown, 4 withdrawn, 3 terminated. 13 Phase 2, 11 Not applicable, 6 Phase 1, 5 Phase 3, 2 Early Phase 1.
Follow Hypothermia: new trials by email Literature Review of Hypothermia trials Research Report on Hypothermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of IV Fluid Warmer for the Prevention of Hypothermia Hypothermia, Hotline - Hypothermia, Shivering | Not applicable | Completed | Shaukat Khanum Memorial Cancer Hospital & Research Centre | 84 | 2025-03-01 | 2025-09-25 |
| Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics. hypothermia - Stroke, Hypothermia Treatment | Recruiting | Capital Medical University | 258 | 2024-10-27 | 2024-12-12 | |
| Combination of Hypothermia and Thrombectomy in Acute Stroke hypothermia - Ischemic Stroke, Large Vessel Occlusion | Phase 3 | Recruiting | University of Freiburg | 400 | 2024-07-07 | 2025-01-06 |
| Role of Hypothermia in Endovascular Stroke Thrombectomy hypothermia, thrombectomy - Stroke, Acute Ischemic | Not applicable | Not yet recruiting | Xinqiao Hospital of Chongqing | 200 | 2023-12-01 | 2023-10-31 |
| Benefit of Hypothermia in OHCA Complicating AMI Hypothermia - Out-Of-Hospital Cardiac Arrest, Myocardial Infarction, Acute | Not applicable | Completed | Yonsei University | 2925 | 2023-11-15 | 2025-05-01 |
| Accidental Hypothermia in Drowning-related OHCA Hypothermia - Hypothermia, Accidental, Hypothermia Due to Cold Environment | Completed | Prehospital Center, Region Zealand | 119 | 2023-10-01 | 2024-03-15 | |
| Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy Metabolic acidosis, microRNA, Hypothermia - Hypoxic-Ischemic Encephalopathy, Asphyxia Perinatal | Completed | Ospedale Buon Consiglio Fatebenefratelli | 45 | 2023-07-18 | 2026-06-05 | |
| Trial of Therapeutic Hypothermia in Patients With ARDS Hypothermia, Neuromuscular Blocking Agents, Standard of care - Respiratory Distress Syndrome, Adult | Phase 2 | Active not recruiting | University of Maryland, Baltimore | 340 | 2021-06-29 | 2026-09-09 |
| Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS Hypothermia, Neuromuscular Blocking Agents, Standard of Care - Respiratory Distress Syndrome, Adult, Sars-CoV2 | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2018-05-01 | 2021-04-30 | |
| Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers Cryotherapy, Vitamins C and E, Vitamins C and E associated with cryotherapy - Inflammation, Oxidative Stress | Not applicable | Completed | Universidade Federal de Santa Maria | 26 | 2017-01-04 | 2017-07-17 |
| Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy Autologous cord blood, Hypothermia - Hypoxic Ischemic Encephalopathy, Cerebral Infarction | Phase 1 / Phase 2 | Withdrawn | Children's Hospital of Fudan University | 2015-09-08 | 2023-12-29 | |
| Preemie Hypothermia for Neonatal Encephalopathy Hypothermia, Normothermic Control - Infant, Newborn, Hypoxia, Brain | Not applicable | Completed | NICHD Neonatal Research Network | 168 | 2015-05-01 | 2024-11-04 |
| NVD in Hypothermic HIE Neonates N-acetylcysteine, NAC, and calcitriol - HIE - Perinatal Hypoxic - Ischemic Encephalopathy | Early Phase 1 | Completed | Medical University of South Carolina | 30 | 2015-01-01 | 2020-12-04 |
| Study of Survivors of Different Types of Cardiac Arrest and Their Neurological Recovery No treatment, Therapeutic hypothermia - Postcardiac Arrest, Pulseless Electrical Activity | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 400 | 2014-01-01 | 2014-01-13 | |
| Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke Hypothermia, Buspirone, Pethidine - Acute Ischemic Stroke | Phase 3 | Terminated | University of Erlangen-Nürnberg Medical School | 98 | 2013-07-01 | 2019-10-02 |
| PREventing CHemotherapy Induced Neuropathy (PreChIN) Hypothermia, Cryocompression - Chemotherapy-induced Peripheral Neuropathy (CIPN) | Not applicable | Completed | National University Hospital, Singapore | 89 | 2013-06-13 | 2017-10-03 |
| Reperfusion With Cooling in Cerebral Acute Ischemia II Mild Hypothermia - Ischemic Stroke, Hypothermia | Not applicable | Withdrawn | WellStar Health System | 2013-02-01 | 2018-09-13 | |
| Incidence and Risk Factors of Postoperative Hypothermia in Cardiac Surgery hypothermia - Postoperative Hypothermia in Patients With Cardiopulmonary Bypass | Completed | Mahidol University | 760 | 2013-01-01 | 2022-04-14 | |
| Safety and Feasibility Study of Targeted Temperature Management After ICH Normothermia, Hypothermia - Intracerebral Hemorrhage | Phase 1 / Phase 2 | Unknown | Thomas Jefferson University | 50 | 2013-01-01 | 2015-08-05 |
| Hypothermia During ECMO to Decrease Brain Injury Hypothermia - Neonatal Respiratory Failure | Not applicable | Withdrawn | Sood, Beena G., MD, MS | 2012-08-01 | 2014-11-18 |
Showing 20 of 37. Sign in to see all of them.
Hypothermia (20) · Hypoxia-Ischemia, Brain (6) · Ischemic Stroke (5) · Stroke (5) · Out-of-Hospital Cardiac Arrest (4) · Asphyxia (2) · Brain Diseases (2) · Brain Injuries, Traumatic (2) · Heart Arrest (2) · Hypoxia, Brain (2) · Myocardial Infarction (2) · Respiratory Distress Syndrome (2) · Acute Lung Injury (1) · Anterior Wall Myocardial Infarction (1) · Argininosuccinic Aciduria (1)
Medical University of South Carolina (2) · NICHD Neonatal Research Network (2) · The University of Texas Health Science Center, Houston (2) · University of Maryland, Baltimore (2) · Assaf-Harofeh Medical Center (1) · Australian and New Zealand Intensive Care Research Centre (1) · Capital Medical University (1) · Children's Hospital of Fudan University (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Mahidol University (1) · Mayo Clinic (1) · Min-Sheng General Hospital (1) · National University Hospital, Singapore (1) · Ospedale Buon Consiglio Fatebenefratelli (1) · Prehospital Center, Region Zealand (1)
United States (15) · Canada (3) · China (3) · Denmark (2) · Germany (2) · New Zealand (2) · Australia (1) · Austria (1) · Brazil (1) · Finland (1) · France (1) · Israel (1) · Italy (1) · Pakistan (1) · Qatar (1)
Abhik Das, PhD (2) · Jeffrey D Hasday, MD (2) · Myra Wyckoff, MD (2) · Seetha Shankaran, MD (2) · Abbot R Laptook, MD (1) · Abbot R. Laptook, MD (1) · Ahmed F Hegazy, MD, FRCPC (1) · Amanda Chan (1) · Ana Igric, MD, FRCSC (1) · Anthony Mullins (1) · Barbara J. Stoll, MD (1) · Barbara Schmidt, MD, MSc (1) · Beena G. Sood (1) · Bradley Yoder, MD (1) · Brenda B. Poindexter, MD MS (1)
PMID 10763759, PMID 15607598, PMID 15607599, PMID 1622910, PMID 17695343, PMID 20847327, PMID 21169065, PMID 21481385, PMID 22805873, PMID 22839656, PMID 23164721, PMID 23896830, PMID 23897243, PMID 24436240, PMID 24509284, PMID 24828363, PMID 25985169, PMID 26222557, PMID 26946139, PMID 26978207, PMID 27145749, PMID 27412659, PMID 29067428, PMID 29137711, PMID 29187242, PMID 29463417, PMID 29496329, PMID 29561203, PMID 30357266, PMID 30592487, PMID 30716413, PMID 31162858, PMID 31356580, PMID 32050997, PMID 32260446, PMID 33189747, PMID 33204336, PMID 34130035, PMID 34152109, PMID 35835616, PMID 36251060, PMID 38833442, PMID 38982000, PMID 39992674, PMID 41298726
U10HD021364 (2), U10HD021373 (2), U10HD021385 (2), U10HD027851 (2), U10HD027853 (2), U10HD027856 (2), U10HD027880 (2), U10HD027904 (2), U10HD034216 (2), U10HD036790 (2), U10HD040492 (2), U10HD040689 (2), U10HD053109 (2), U10HD068244 (2), U10HD068263 (2)