13 completed, 3 recruiting, 3 unknown, 2 active not recruiting. 11 Phase 2, 9 Phase 3, 5 Phase 1, 1 Phase 4.
Follow Hydrocortisone Sodium Succinate: new trials by email Literature Review of Hydrocortisone Sodium Succinate trials Research Report on Hydrocortisone Sodium Succinate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Myelodysplastic Syndrome | Phase 1 | Recruiting | Children's Oncology Group | 36 | 2025-02-04 | 2026-08-25 |
| A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia Biospecimen Collection, Bone Marrow Aspiration, Calaspargase Pegol - Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia | Phase 2 | Active not recruiting | Children's Oncology Group | 78 | 2024-01-08 | 2026-08-25 |
| A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat Anti-CD123 ADC IMGN632, Bone Marrow Aspiration and Biopsy, Cytarabine - Recurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Withdrawn | Children's Oncology Group | 2023-08-01 | 2023-09-01 | |
| Venetoclax Basket Trial for High Risk Hematologic Malignancies Venetoclax, Azacitidine, Cytarabine - Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary | Phase 1 | Recruiting | Andrew E. Place, MD | 30 | 2023-03-29 | 2026-03-12 |
| A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL) 3-Dimensional Conformal Radiation Therapy, Asparaginase Erwinia chrysanthemi, Biospecimen Collection - Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 461 | 2020-12-17 | 2026-09-01 |
| Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS) hydrocortisone sodium succinate, Saline - Vasoplegia, Cardiac Surgery | Phase 3 | Unknown | Instituto do Coracao | 140 | 2020-03-01 | 2020-03-10 |
| Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis Vitamin C, Hydrocortisone, Complex B - Sepsis, Septic Shock | Phase 3 | Completed | IMSS Hospital General de Zona 11, Piedras Negras | 19 | 2019-09-01 | 2020-10-19 |
| Vitamin C, Thiamine, and Steroids in Sepsis Vitamin C, Thiamine, Hydrocortisone - Sepsis | Phase 3 | Completed | Emory University | 501 | 2018-08-22 | 2021-04-13 |
| Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis Mesalazine, hydrocortisone sodium succinate, Mesalazine with hydrocortisone sodium succinate - Ulcerative Colitis, Unspecified | Phase 4 | Unknown | Xijing Hospital of Digestive Diseases | 528 | 2017-05-01 | 2017-04-12 |
| Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement Azacitidine, Biospecimen Collection, Computed Tomography - Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 78 | 2017-04-01 | 2025-02-27 |
| A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma Temsirolimus, Etoposide, Cyclophosphamide - Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma | Phase 1 | Completed | Therapeutic Advances in Childhood Leukemia Consortium | 16 | 2015-07-03 | 2023-07-27 |
| Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma Bortezomib, Cyclophosphamide, Cytarabine - Adult T Acute Lymphoblastic Leukemia, Ann Arbor Stage II Adult Lymphoblastic Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 847 | 2014-10-04 | 2026-10-21 |
| Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma DNR, VCR, PEG-asp - Acute Lymphocytic Leukemia, Adult Lymphoblastic Lymphoma | Phase 2 | Terminated | University of California, San Diego | 31 | 2014-01-01 | 2022-05-02 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Clofarabine, Cyclophosphamide, Cytarabine - B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like | Phase 3 | Completed | National Cancer Institute (NCI) | 5949 | 2012-02-29 | 2026-06-02 |
| EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL) EZN-3042, Cytarabine, Doxorubicin - Lymphoblastic Leukemia, Acute, Lymphoblastic Leukemia, Acute, Childhood | Phase 1 | Terminated | Therapeutic Advances in Childhood Leukemia Consortium | 6 | 2010-08-24 | 2024-02-01 |
| Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia cyclophosphamide, cytarabine, dexamethasone - Leukemia | Phase 2 | Unknown | Ohio State University Comprehensive Cancer Center | 180 | 2009-01-01 | 2014-01-10 |
| Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Asparaginase, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 63 | 2008-07-14 | 2020-04-13 |
| Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study hydrocortisone - Sepsis | Phase 2 | Completed | University Hospital Southampton NHS Foundation Trust | 21 | 2008-04-01 | 2016-05-06 |
| Prospective Randomized Study of Glucocorticoids in the Impact of the Liver Function and the Prognosis After Hepatectomy of HCC Hydrocortisone sodium succinate - Some Studies Shows That the Steroid Can Reduce the Injury of the I/R of the Liver | Suspended | Eastern Hepatobiliary Surgery Hospital | 60 | 2008-04-01 | 2012-05-31 | |
| ALL Adult Consortium Trial: Adult ALL Trial Doxorubicin, Cytarabine, Methotrexate - Acute Lymphoblastic Leukemia | Phase 2 | Completed | Dana-Farber Cancer Institute | 112 | 2007-04-01 | 2025-06-12 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (8) · Burkitt Lymphoma (6) · Leukemia (6) · Leukemia, Biphenotypic, Acute (4) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (3) · Recurrence (3) · Sepsis (3) · Dendritic Cell Sarcoma, Interdigitating (2) · Lymphoma (2) · Shock, Septic (2) · Adrenal Insufficiency (1) · Cardiotoxicity (1) · Colitis, Ulcerative (1) · Down Syndrome (1) · Leukemia, Myeloid, Acute (1)
Children's Oncology Group (7) · National Cancer Institute (NCI) (5) · Therapeutic Advances in Childhood Leukemia Consortium (2) · Andrew E. Place, MD (1) · Dana-Farber Cancer Institute (1) · Eastern Hepatobiliary Surgery Hospital (1) · Emory University (1) · Hadassah Medical Organization (1) · IMSS Hospital General de Zona 11, Piedras Negras (1) · Instituto do Coracao (1) · Ohio State University Comprehensive Cancer Center (1) · University Hospital Southampton NHS Foundation Trust (1) · University of California, San Diego (1) · Xijing Hospital of Digestive Diseases (1)
United States (15) · Canada (9) · Australia (8) · Puerto Rico (4) · New Zealand (3) · United Kingdom (3) · France (2) · Austria (1) · Belgium (1) · Brazil (1) · China (1) · Germany (1) · Ireland (1) · Israel (1) · Italy (1)
Alexandra M Stevens (1) · Andrew E Place, MD, PhD (1) · Andrew Wolf, MBBChir MD (1) · Barbara L. Asselin, MD (1) · Carrol Gamble, PhD (1) · Catherine Patte, MD (1) · Charles L Sprung, MD (1) · Daniel DeAngelo, MD (1) · David T Teachey (1) · Diana M Gibb, MBChB MD (1) · Didier Keh, MD (1) · Didier Pittet, MD (1) · Djillali Annane, MD (1) · Elizabeth Raetz, MD (1)
PMID 10820362, PMID 12011123, PMID 17132719, PMID 17138821, PMID 18184957, PMID 18371107, PMID 18493992, PMID 19020548, PMID 19895612, PMID 21496005, PMID 22073145, PMID 22215753, PMID 24276047, PMID 29812996, PMID 30117142, PMID 30953543, PMID 31801567, PMID 32007132, PMID 32317004, PMID 32496902, PMID 33242441, PMID 33620405, PMID 35271306, PMID 35622074, PMID 36603187, PMID 36853612, PMID 37890117, PMID 38457359, PMID 38867582, PMID 39121442, PMID 41671463
U10CA180886 (6), U10CA098543 (4), U10CA030969 (1), UM1CA228823 (1)