6 completed, 4 unknown, 1 terminated, 1 withdrawn. 12 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Unknown 4, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Glucosamine: new trials by email Literature Review of Glucosamine trials Research Report on Glucosamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial. HAIC, TACE, FOLFOX - Hepatocellular Carcinoma | Phase 2 / Phase 3 | Terminated | Peking University | 18 | 2021-12-24 | 2025-12-18 |
| A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study glucosamine sulphate 1500mg and meloxicam 15mg, Glucosamine sulfate 1500mg and chondroitin sulfate 1200mg, Placebos - Knee Osteoarthritis | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2019-01-01 | 2022-04-18 | |
| Clinical Study of Non-inferiority With Participants Diagnosed With Primary Knee OA (GLACIAL) Glucosamine and chondroitin sulfate combination (Eurofarma), Glucosamine and chondroitin sulfate combination (Zodic) - Osteoarthritis of Knee | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 627 | 2016-12-05 | 2019-10-09 |
| Study of Association of Anti-inflammatory and Anti-rheumatic Meloxicam and Glucosamine, Meloxicam, Glucosamine - Osteoarthritis | Phase 3 | Unknown | Zodiac Produtos Farmaceuticos S.A. | 375 | 2015-07-01 | 2015-05-19 |
| Effect of Glucosamine on Intraocular Pressure Placebo three times a day, glucosamine sulfate 1500 mg three times a day - Intraocular Pressure Changes After Glucosamine Sulfate Consumption. | Phase 3 | Unknown | Shahid Beheshti University of Medical Sciences | 41 | 2014-07-01 | 2015-05-08 |
| Study With Chondroitin Sulfate and Glucosamine Sulfate (in Dosage Capsule and Sachet) in Treating Osteoarthritis Chondroitin sulfate + Glucosamine sulfate - Osteoarthritis | Phase 3 | Unknown | Azidus Brasil | 320 | 2011-11-01 | 2011-02-10 |
| Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee Glucosamine sulphate and chondroitin sulphate association, Cosamin DS® (Nutramax) - Osteoarthritis of the Knee | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 100 | 2010-08-01 | 2023-02-08 |
| Effectiveness of Glucosamine + Chondroitin in Osteoarthrosis EMS Chondroitin Sulfate + Glucosamine Sulfate (Oral powder), EMS Chondroitin Sulfate 1200mg + Glucosamine Sulfate 1500mg (hard capsules), Zodiac: Chondroitin Sulfate 1200mg + Glucosamine Sulfate 1500mg (Oral powder) - Osteoarthrosis | Phase 3 | Completed | Azidus Brasil | 280 | 2009-10-01 | 2013-02-25 |
| Efficacy and Safety of Glucosamine Sulfate and Chondroitin Sulfate Combination in Treatment of Knee Osteoarthritis glucosamine sulfate /chondroitin sulfate - capsules, glucosamine sulfate /chondroitin sulfate - sachet, Cosamin DS® - Knee Osteoarthritis | Phase 3 | Completed | Ache Laboratorios Farmaceuticos S.A. | 922 | 2009-02-01 | 2013-12-13 |
| Glucosamine Unum In Die [Once A Day] Efficacy (GUIDE) Trial: Glucosamine Sulfate in Patients With Knee Osteoarthritis Glucosamine sulfate, Acetaminophen - Knee Osteoarthritis | Phase 3 | Completed | Rottapharm | 300 | 2000-05-01 | 2006-09-19 |
| Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT) glucosamine, chondroitin sulfate, glucosamine and chondroitin sulfate combined - Osteoarthritis | Phase 3 | Completed | US Department of Veterans Affairs | 1588 | 2000-04-01 | 2009-01-21 |
| Non-inferiority Study of the Glucosamine Sulfate + Chondroitin Sulfate Association Capsule in Comparison to the CONDROFLEX® Product in Osteoarthrosis of the Knee Glucosamine sulfate + chondroitin sulfate - MANTECORP, Glucosamine sulfate + chondroitin sulfate - CONDROFLEX - Osteoarthritis, Knee | Phase 3 | Unknown | Mantecorp Industria Quimica e Farmaceutica Ltd. | 250 | 2010-07-29 |
Osteoarthritis (7) · Osteoarthritis, Knee (6) · Carcinoma, Hepatocellular (1) · Pain (1)
Eurofarma Laboratorios S.A. (3) · Azidus Brasil (2) · Ache Laboratorios Farmaceuticos S.A. (1) · Mantecorp Industria Quimica e Farmaceutica Ltd. (1) · Peking University (1) · Rottapharm (1) · Shahid Beheshti University of Medical Sciences (1) · US Department of Veterans Affairs (1) · Zodiac Produtos Farmaceuticos S.A. (1)
Brazil (4) · China (1) · Iran (1) · Portugal (1) · Spain (1) · United States (1)
Cristiano F. Zerbini, Phd/MD (1) · Edio Costa, Doctor (1) · Gabriel Herrero-Beaumont, MD (1) · Marise L. Castro, Phd/MD (1) · Xiaodong Wang, MD (1)
PMID 16495392, PMID 17265490, PMID 18821708, PMID 30657100, PMID 33468249