120 completed, 53 unknown, 23 recruiting, 9 not yet recruiting. 143 Not applicable, 18 Phase 4, 5 Phase 2, 5 Phase 3, 2 Phase 1.
Follow General Anesthesia: new trials by email Literature Review of General Anesthesia trials Research Report on General Anesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia Feasibility Trial Monitored Anesthesia Care (MAC), Soft Tissue Infiltration with Local Anesthetic (STILA), General Anesthesia - Hip Fracture Surgeries, Intertrochanteric Fracture | Not applicable | Recruiting | NYU Langone Health | 140 | 2026-10-27 | 2026-10-29 |
| Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia sarcopenia, Non-sarcopenia, General Anesthesia - Sarcopenia, Nerve Block | Not yet recruiting | Chang Gung Memorial Hospital | 150 | 2026-09-01 | 2026-08-11 | |
| Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery. Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy - Fraily, Abdominal Surgery | Not applicable | Not yet recruiting | Ente Ospedaliero Ospedali Galliera | 100 | 2026-09-01 | 2026-03-20 |
| Cervical Erector Spinae Plane Block in Proximal Humeral Fracture Surgery, A Motor-Sparing Block Cervical erector spinae plane block, General anesthesia - Cervical, Erector Spinae Plane Block | Not applicable | Recruiting | Menoufia University | 44 | 2026-08-01 | 2026-09-17 |
| EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY General Anesthesia, cervical plexus block - General Anesthesia, Cervical Plexus Block | Not applicable | Not yet recruiting | Harran University | 60 | 2026-07-30 | 2026-05-18 |
| Unilateral Spinal vs General Anaesthesia in Low EF Patients: A Hemodynamic Comparison Unilateral spinal anesthesia, General anesthesia - Hemodynamic (MAP) Stability | Enrolling by invitation | Sargodha Medical College | 78 | 2026-07-05 | 2026-08-10 | |
| Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 390 | 2026-06-01 | 2026-10-26 |
| Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia Spinal Anesthesia, General Anesthesia, Propofol - Knee Stiffness After Total Knee Arthroplasty | Phase 4 | Recruiting | Duke University | 128 | 2026-06-01 | 2026-06-03 |
| Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation spinal anesthesia, General Anesthesia - Spinal Anesthesia, Percutaneous Nephrolithotomy | Not applicable | Not yet recruiting | Tanta University | 70 | 2026-05-30 | 2025-08-11 |
| Spinal Versus General Anesthesia in Open Simple Prostatectomy Spinal anesthesia, General anesthesia - Urologic Neoplasms, Benign Prostatic Hyperplasia | Not applicable | Recruiting | Hitit University | 80 | 2026-04-29 | 2026-06-16 |
| Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke General Anesthesia, Sedoanalgesia - Acute Ischemic Stroke | Completed | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 481 | 2026-04-01 | 2026-04-08 | |
| Safety and Efficacy of Conscious Sedation Versus General Anesthesia in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation conscious sedation, General Anesthesia (control group) - Atrial Fibrillation (Paroxysmal) | Not applicable | Active not recruiting | Beijing Anzhen Hospital | 224 | 2026-04-01 | 2026-10-28 |
| Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2 General Anesthesia, Procedural sedation - Ischemic Stroke, Anterior Cerebral Circulation | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 958 | 2026-03-24 | 2026-09-02 |
| Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG) - Total Knee Arthroplasty (TKA) | Phase 1 / Phase 2 | Recruiting | University of Chicago | 150 | 2026-03-11 | 2026-06-26 |
| Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study spinal anesthesia, General Anesthesia - Placenta Accreta Spectrum | Not yet recruiting | Gaziantep City Hospital | 50 | 2026-02-01 | 2026-02-12 | |
| Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia - Kidney Stones | Not applicable | Not yet recruiting | Zagazig University | 90 | 2026-01-12 | 2026-01-22 |
| Reinforcement Learned Automated Anesthesia Systems During Painless Abortion AI Controlled General Anesthesia, General Anesthesia - Painless Abortion, Artificial Intelligence (AI) | Not applicable | Not yet recruiting | Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. | 167 | 2025-09-08 | 2025-08-20 |
| Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial Spinal Anesthesia, General Anesthesia - NMIBC, TURBT | Not applicable | Not yet recruiting | National Taiwan University Hospital | 370 | 2025-08-01 | 2025-05-21 |
| Ultrasound Guided External Oblique and Rectus Abdominis Plane Block (EXORA) on Neuroendocrine Stress Response in Adults Undergoing Umbilical Hernia Surgery General anesthesia, External oblique and rectus abdominis plane (EXORA) block - Ultrasound, External Oblique | Not applicable | Recruiting | Tanta University | 100 | 2025-08-01 | 2026-01-08 |
| General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty Spinal anesthesia, General anesthesia - General Anesthesia, Spinal Anesthesia | Not applicable | Recruiting | Tanta University | 100 | 2025-07-19 | 2025-07-22 |
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Pain, Postoperative (21) · Agnosia (11) · Hip Fractures (10) · Breast Neoplasms (8) · Postoperative Complications (5) · Postoperative Nausea and Vomiting (5) · Ischemic Stroke (4) · Urinary Bladder Neoplasms (4) · Emergence Delirium (3) · Pain (3) · Pancreatic Neoplasms (3) · Patient Satisfaction (3) · Postoperative Cognitive Complications (3) · Anxiety Disorders (2) · Aortic Valve Stenosis (2)
Tanta University (10) · Cairo University (8) · Makassed General Hospital (6) · RenJi Hospital (4) · Beijing Tiantan Hospital (3) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (3) · Medical University of Lublin (3) · Seoul National University Hospital (3) · The First Hospital of Qinhuangdao (3) · Zagazig University (3) · Air Force Military Medical University, China (2) · Antalya Training and Research Hospital (2) · Assiut University (2) · CHU de Reims (2) · China Medical University, China (2)
Egypt (37) · China (33) · Turkey (Türkiye) (28) · United States (25) · France (9) · South Korea (8) · Canada (7) · Belgium (6) · Croatia (6) · Italy (6) · Lebanon (6) · Poland (5) · Brazil (4) · Germany (4) · Sweden (4)
Zoher Naja, MD (3) · Bozidar Duplancic (2) · Changhong Miao (2) · Giorgio Danelli, MD (2) · Hrvoje Vucemilovic (2) · Ivan Velat (2) · Ivo Juginovic (2) · Jin-Tae Kim (2) · Jonathan P Wanderer, MD, MPhil (2) · Qianjin Liu (2) · Ruben Kovac (2) · Svjetlana Dosenovic (2) · Abd-Elazeem A Elbakry, M.D (1)
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R01AG090860 (1), R34HD060741 (1)