50 completed, 4 withdrawn, 2 not yet recruiting, 1 active not recruiting. 58 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 58 | Completed 50, Withdrawn 4, Not yet recruiting 2, Active not recruiting 1, Terminated 1 |
| Phase 2 | 4 | Completed 3, Withdrawn 1 |
Follow Fluconazole: new trials by email Literature Review of Fluconazole trials Research Report on Fluconazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single-center, Randomized, Open-label, Parallel-design Clinical Study to Evaluate the Pharmacokinetic Effects of Itraconazole, Fluconazole or Efavirenz on a Single Dose of Clifutinib in Healthy Participants Clifutinib, Itraconazole, fluconazole - Healthy Adult Subject | Phase 1 | Not yet recruiting | Sunshine Lake Pharma Co., Ltd. | 80 | 2026-12-31 | 2026-04-27 |
| Drug-Drug Interactions of JMKX003142 in Healthy Participants JMKX003142 tablets, Fluconazole Capsules, Cocktail Substrates (Midazolam Oral Solution, Rosuvastatin Calcium Tablets, and Digoxin Tablets) - ADPKD (Autosomal Dominant Polycystic Kidney Disease) | Phase 1 | Not yet recruiting | Jemincare | 112 | 2026-05-11 | 2026-05-04 |
| A Study of Olomorasib (LY3537982) in Healthy Participants Olomorasib, Fluconazole - Healthy | Phase 1 | Completed | Eli Lilly and Company | 15 | 2026-03-02 | 2026-05-19 |
| A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults Setidegrasib, Fluconazole, Carbamazepine - Healthy Volunteer | Phase 1 | Active not recruiting | Astellas Pharma Global Development, Inc. | 54 | 2026-02-03 | 2026-08-27 |
| A Study to Learn if the Study Medicine Called Fluconazole Changes How the Other Body Processes the Study Medicine PF-07248144 PF-07248144, Fluconazole - Healthy Adults | Phase 1 | Completed | Pfizer | 12 | 2025-08-26 | 2026-06-09 |
| A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323. EDP-323, Itraconazole, carbamazepine - RSV Infection, Drug Drug Interaction (DDI) | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 48 | 2025-01-27 | 2025-07-01 |
| A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants LY4100511 (DC-853), Itraconazole, Fluconazole - Healthy | Phase 1 | Completed | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company | 50 | 2024-04-03 | 2025-04-27 |
| A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults ALXN2080, Itraconazole, Fluconazole (AxMP) - Healthy | Phase 1 | Completed | Alexion Pharmaceuticals, Inc. | 60 | 2024-01-10 | 2024-06-20 |
| Drug Interactions Trial of Methoxyethyl Etomidate Hydrochloride rifampicin, Fluconazole, Omeprazole - Interaction Drug Food | Phase 1 | Completed | Ahon Pharmaceutical Co., Ltd. | 68 | 2023-12-04 | 2025-02-14 |
| Effect of Fluconazole on Pharmacokinetics of SHR2554 in Healthy Subjects SHR2554 Tablets, Fluconazole Capsules - Malignant Tumor | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 18 | 2023-02-28 | 2023-04-04 |
| Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects CTP-543, Fluconazole - Health Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 18 | 2022-07-11 | 2022-08-30 |
| HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI Itraconazole 200 mg, Fluconazole 400 mg, Rifampin 600 mg - Relapsed or Refractory Lymphoma | Phase 1 | Completed | Hutchmed | 59 | 2022-06-01 | 2024-03-06 |
| Comparison of Efficacy of Single Oral Dose Fluconazole and Itraconazole in Patients With Pityriasis Versicolor Fluconazole, Itraconazole - Tinea Versicolor | Phase 1 | Completed | Combined Military Hospital Abbottabad | 164 | 2022-03-01 | 2023-05-17 |
| A Study in Healthy Men to Test How Fluconazole Influences the Amount of BI 425809 in the Blood BI 425809, fluconazole - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 15 | 2021-10-19 | 2026-05-04 |
| Drug Interaction Study of ALXN2050 With Fluconazole and Rifampin in Healthy Adult Participants ALXN2050, Fluconazole, Rifampin - Healthy | Phase 1 | Completed | Alexion Pharmaceuticals, Inc. | 16 | 2021-06-07 | 2026-07-16 |
| A Study to Evaluate the Effect of Fluconazole, Bupropion, or Itraconazole on the Drug Levels and Safety of BMS-986235 Fluconazole, Bupropion, Itraconazole - Healthy Participants | Phase 1 | Withdrawn | Bristol-Myers Squibb | 2021-04-01 | 2022-03-25 | |
| Drug-Drug Interaction Study Between Fluconazole and EDP-938 in Healthy Subjects EDP-938, Fluconazole - RSV Infection | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 24 | 2021-03-12 | 2021-05-04 |
| A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects Fedratinib, Fluconazole - Healthy Volunteers | Phase 1 | Completed | Celgene | 29 | 2021-01-12 | 2021-11-29 |
| Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies Zanubrutinib, Fluconazole, Diltiazem - B-cell Malignancies | Phase 1 | Completed | BeiGene | 26 | 2020-11-15 | 2024-10-26 |
| A Study to Evaluate the Effect of Pharmacokinetics (PK) of Acalabrutinib and Its Active Metabolite (ACP-5862) When Administered Alone and With Moderate CYP3A4 Inhibitors Fluconazole or Isavuconazole in Healthy Adult Participants Acalabrutinib, Fluconazole, Isavuconazole - Healthy Volunteers | Phase 1 | Completed | Acerta Pharma BV | 30 | 2020-01-03 | 2021-12-01 |
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HIV Infections (3) · AIDS-Related Complex (2) · Acquired Immunodeficiency Syndrome (2) · Candidiasis (2) · Lymphoma (2) · Lymphoma, Large B-Cell, Diffuse (2) · Mycoses (2) · Neoplasms (2) · Recurrence (2) · Respiratory Syncytial Virus Infections (2) · AIDS-Related Opportunistic Infections (1) · Alzheimer Disease (1) · Bacterial Infections (1) · Candidemia (1) · Carcinoma, Non-Small-Cell Lung (1)
Pfizer (5) · Boehringer Ingelheim (3) · Eli Lilly and Company (3) · Enanta Pharmaceuticals, Inc (3) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Alexion Pharmaceuticals, Inc. (2) · Bristol-Myers Squibb (2) · Dr. Reddy's Laboratories Limited (2) · Eisai Inc. (2) · F2G Ltd (2) · Jiangsu HengRui Medicine Co., Ltd. (2) · Millennium Pharmaceuticals, Inc. (2) · Acerta Pharma BV (1) · Ahon Pharmaceutical Co., Ltd. (1) · Astellas Pharma Global Development, Inc. (1)
United States (30) · China (5) · Canada (3) · Germany (3) · United Kingdom (3) · Belgium (2) · South Korea (2) · Spain (2) · Australia (1) · India (1) · Kenya (1) · Pakistan (1) · Peru (1) · South Africa (1) · Switzerland (1)
Gaetano Morelli, MD (2) · A Stewart (1) · Cobb M (1) · Daniel Benjamin, MD (1) · David R Mathews, MD (1)
PMID 15470330, PMID 27154174, PMID 31673875, PMID 34083232, PMID 34083236, PMID 36001108, PMID 36480811, PMID 36780493, PMID 37036155, PMID 42008658
2014 (1), 2017 (1), 2025 (1), P30MH075673 (1)