6 completed, 1 not yet recruiting, 1 terminated, 1 withdrawn. 9 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 6, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 3 | 1 | Withdrawn 1 |
Follow Flecainide: new trials by email Literature Review of Flecainide trials Research Report on Flecainide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| N-of-1 in ATS and MEPPC Flecainide, Flecainide + beta-blocker - Andersen Tawil Syndrome, Multifocal Ectopic Purkinje-related Premature Contractions | Phase 2 | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 10 | 2025-03-01 | 2025-01-29 |
| Pilot Randomized Trial With Flecainide in ARVC Patients Flecainide Pill, Placebo - Arrhythmogenic Right Ventricular Cardiomyopathy | Phase 2 | Completed | University of Rochester | 22 | 2019-07-23 | 2024-08-20 |
| Comparison of Effectiveness of Ranolazine Plus Metoprolol Combination vs. FlecainidE pluS Metoprolol Combination in ATrial Fibrillation Recurrences FOllowing PhaRmacological or Electrical CardioverSion of AtRial Fibrillation Ranolazine plus Metoprolol Combination, FlecainidE pluS Metoprolol Combination - Atrial Fibrillation, Recurrence | Phase 2 / Phase 3 | Withdrawn | Elpen Pharmaceutical Co. Inc. | 2018-09-01 | 2019-05-13 | |
| INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT) Flecainide Acetate - Paroxysmal Atrial Fibrillation (PAF) | Phase 2 | Completed | InCarda Therapeutics, Inc. | 176 | 2018-05-29 | 2024-05-14 |
| Safety and Efficacy of THN102 on Sleepiness in Narcoleptic Patients Active comparator: Modafinil + placebo, THN102 300/3, THN102 300/27 - Narcolepsy | Phase 2 | Completed | Theranexus | 51 | 2016-09-01 | 2020-09-04 |
| Premature Ventricular Contractions (PVCs) and Blood Pressure Control PVC Suppression using Flecainide, No PVC Suppression using Placebo - Ventricular Premature Complexes, Blood Pressure | Phase 2 | Terminated | University of Wisconsin, Madison | 8 | 2013-02-01 | 2019-02-22 |
| A Comparison of the Drug Therapy Versus Re-Ablation Anti-Arrhythmia Agents (propafenone, flecainide, and/or sotalol, or amiodarone), re-ablation procedure, ILR implantation - Paroxysmal Atrial Fibrillation, Failed First Radiofrequency Ablation Procedure | Phase 2 | Completed | Meshalkin Research Institute of Pathology of Circulation | 154 | 2007-11-01 | 2012-10-18 |
| Flecainide in Treating Patients With Chronic Neuropathic Pain flecainide acetate - Pain | Phase 2 | Completed | Eastern Cooperative Oncology Group | 20 | 1998-05-04 | 2023-06-15 |
| Cardiac Arrhythmia Pilot Study (CAPS) encainide, moricizine, flecainide - Arrhythmia, Cardiovascular Diseases | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1982-09-01 | 2012-04-27 |
Atrial Fibrillation (3) · Arrhythmias, Cardiac (2) · Andersen Syndrome (1) · Arrhythmogenic Right Ventricular Dysplasia (1) · Cardiovascular Diseases (1) · Heart Diseases (1) · Narcolepsy (1) · Pain (1) · Recurrence (1) · Ventricular Premature Complexes (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Eastern Cooperative Oncology Group (1) · Elpen Pharmaceutical Co. Inc. (1) · InCarda Therapeutics, Inc. (1) · Meshalkin Research Institute of Pathology of Circulation (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Theranexus (1) · University of Rochester (1) · University of Wisconsin, Madison (1)
United States (3) · Belgium (2) · France (1) · Netherlands (1) · Russia (1)
Allan Barker (1) · Charles F. Von Gunten, MD, PhD (1) · Craig Pratt (1) · David Richardson (1) · Evgeny Pokushalov, MD, PhD (1) · Israel Stein (1) · J. Bigger (1) · Lawrence Griffith (1) · Luiz Belardinelli, MD (1) · Michael Sather (1) · Mohamed H Hamdan, MD, MBA (1) · Pierre Theroux (1) · Raymond Woosley (1) · Robert Capone (1) · Toshio Akiyama (1)
PMID 18073252, PMID 23748210, PMID 35196871, PMID 37979797, PMID 38613545
2015 (1), R34HL143372 (1)