8 completed, 8 recruiting, 1 active not recruiting, 1 terminated. 10 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 5, Recruiting 2, Active not recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 4 | Recruiting 4 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 1, Withdrawn 1 |
Follow EGD: new trials by email Literature Review of EGD trials Research Report on EGD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trans-nasal Endoscopy for Bariatric Patients Transnasal Endoscopy, Esophagogastroduodenoscopy - Obesity, Obesity, Morbid | Not applicable | Recruiting | Christopher C. Thompson, MD, MSc | 100 | 2026-04-20 | 2026-06-25 |
| An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis Biopsy Procedure, Biospecimen Collection, EP2/EP4 Antagonist TPST-1495 - Colorectal Carcinoma, Familial Adenomatous Polyposis | Phase 2 | Recruiting | National Cancer Institute (NCI) | 38 | 2026-03-31 | 2026-09-14 |
| Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer Biopsy, Biospecimen Collection, Breath Test - Gastric Carcinoma | Not applicable | Recruiting | City of Hope Medical Center | 240 | 2024-06-27 | 2026-03-13 |
| Obeticholic Acid for Prevention in Barrett's Esophagus Biospecimen Collection, Esophageal Biopsy, Esophagogastroduodenoscopy - Barrett Esophagus, Esophageal Adenocarcinoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 30 | 2024-01-03 | 2026-08-11 |
| Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma Biospecimen Collection, Computed Tomography, Endoscopic Ultrasound - Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 99 | 2023-11-21 | 2026-10-01 |
| Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma Zanubrutinib, Rituximab, Patient Observation - Mantle Cell Lymphoma | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 421 | 2023-10-20 | 2026-10-02 |
| GCC Agonist Signal in the Small Intestine Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy - Barrett Esophagus, Gastroesophageal Reflux Disease | Phase 1 | Completed | University of Wisconsin, Madison | 43 | 2022-11-30 | 2026-04-07 |
| Comparative Study of MCCE With/Without Tether vs Conventional Upper Endoscopy in Patients With Upper Abdominal Symptoms MCC/MCC-T, Standard gastroscopy - Upper Gastrointestinal Symptoms | Not applicable | Completed | AnX Robotica Corp. | 27 | 2021-02-10 | 2026-05-27 |
| Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus Cytosponge, Transnasal Endoscopy (TNE), Esophagogastroduodenoscopy - Barrett Esophagus, GERD | Not applicable | Completed | University of North Carolina, Chapel Hill | 24 | 2020-08-11 | 2023-05-08 |
| Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC EsoGuard (lab assay), Esophagogastroduodenoscopy - Barrett Esophagus, Esophageal Adenocarcinoma | Not applicable | Active not recruiting | Lucid Diagnostics, Inc. | 784 | 2020-06-18 | 2026-09-21 |
| Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer Atezolizumab, Bevacizumab, External Beam Radiation Therapy - Stage III Hepatocellular Carcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 85 | 2019-09-19 | 2026-10-05 |
| Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study Esophagogastroduodenoscopy with high definition-white light end endoscopy (HD-WLE) and narrow band imaging (NBI), Olympus Disposable Distal Attachment Cap - Barrett Esophagus | Not applicable | Terminated | Washington University School of Medicine | 100 | 2017-12-22 | 2022-09-01 |
| Evaluation of Performance Characteristics of Capsule Endoscopy With PillCam UGI Capsule Compared to Standard Endoscopy Pill cam, EGD - Barrett Esophagus | Completed | Midwest Biomedical Research | 21 | 2017-05-03 | 2018-01-19 | |
| Non-endoscopic Brushing of the Esophagus Using a Non-endoscopic Inflatable Balloon of the Esophagus in Screening for Barrett Esophagus non-endoscopic inflatable balloon for the esophagus, Questionnaire Administration, Laboratory Biomarker Analysis - Barrett Esophagus | Not applicable | Completed | Case Comprehensive Cancer Center | 156 | 2015-07-01 | 2019-11-06 |
| Functional Dyspepsia Microbiome Study EGD, Collection of Stool Specimens - Functional Dyspepsia | Completed | Children's Mercy Hospital Kansas City | 40 | 2015-01-01 | 2020-10-06 | |
| Esophageal Cytology With FISH in Detecting Esophageal Cancer Cytology Specimen Collection Procedure, Esophagogastroduodenoscopy, Laboratory Biomarker Analysis - Dysphagia, Dysplasia | Not applicable | Completed | OHSU Knight Cancer Institute | 50 | 2014-02-01 | 2017-05-11 |
| Endosonography For Right Side Acute Intestinal Mal-Symptoms (EFRAIM- Study) EGD, EUS - Abdominal Pain | Not applicable | Unknown | Technical University of Munich | 240 | 2010-01-01 | 2010-03-04 |
| Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma Balloon Capsule Device, Endoscopy - Barrett's Esophagus, Esophageal Neoplasm | Recruiting | Case Western Reserve University | 2000 | 2005-10-01 | 2026-08-10 | |
| Novel Imaging Techniques in Barrett's Esophagus NBI-AFI imaging, Standard Endoscopy - Barrett Esophagus, Gastroesophageal Reflux | Not applicable | Completed | Midwest Biomedical Research | 130 | 2005-10-01 | 2012-10-29 |
| Enhancing Detection of Small Esophageal Varices by PillCam ESO Capsule endoscopy (PillCam ESO), EGD, Capsule endoscopy (PillCam ESO) with abdominal binder - Esophageal Varices | Phase 3 | Withdrawn | Medical College of Wisconsin | 2015-06-19 |
Barrett Esophagus (9) · Gastroesophageal Reflux (4) · Adenocarcinoma Of Esophagus (3) · Abdominal Pain (1) · Adenomatous Polyposis Coli (1) · Carcinoma, Hepatocellular (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Deglutition Disorders (1) · Digestive System Diseases (1) · Esophageal Neoplasms (1) · Esophageal Squamous Cell Carcinoma (1) · Esophageal and Gastric Varices (1) · Esophagitis (1) · Gastrointestinal Diseases (1)
Mayo Clinic (2) · Midwest Biomedical Research (2) · National Cancer Institute (NCI) (2) · Alliance for Clinical Trials in Oncology (1) · AnX Robotica Corp. (1) · Case Comprehensive Cancer Center (1) · Case Western Reserve University (1) · Children's Mercy Hospital Kansas City (1) · Christopher C. Thompson, MD, MSc (1) · City of Hope Medical Center (1) · Lucid Diagnostics, Inc. (1) · Medical College of Wisconsin (1) · OHSU Knight Cancer Institute (1) · Technical University of Munich (1) · University of North Carolina, Chapel Hill (1)
United States (18) · Netherlands (2) · Germany (1)
Prateek Sharma, MD (2) · Alexander Meining, Prof. (1) · Amitabh Chak (1) · Amitabh Chak, MD (1) · Andrew Kaz, MD (1) · Christopher C. Thompson, MD, MSc (1) · Christopher L. Hallemeier, MD (1) · Craig A Friesen, MD (1) · David R Cave, MD, PhD (1) · David S Weinberg (1) · Ganapathy Prasad, M.D. (1) · Gary W Falk, MD, MS (1) · Jean Wang, MD (1) · John Dumont, D.O. (1) · John Hunter (1)
PMID 22178570, PMID 22315471, PMID 38686933
P30CA014520 (2), UG1CA242635 (2), P30CA033572 (1), P30CA043703 (1), P30CA046592 (1), P30CA069533 (1), P50CA150964 (1), R01CA274985 (1), R01CA294704 (1), U54CA163060 (1), UG1CA242596 (1), UG1CA242632 (1)