4 completed, 2 not yet recruiting, 1 suspended, 1 terminated. 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 4, Not yet recruiting 2, Suspended 1, Terminated 1, Withdrawn 1 |
Follow Dipyrone: new trials by email Literature Review of Dipyrone trials Research Report on Dipyrone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Non-opioid Drugs in Addition to Opioid Therapy for Cancer Pain Management Metamizole, Ibuprofen, Placebo - Cancer Pain, Cancer Palliative Care | Phase 3 | Not yet recruiting | University Hospital, Basel, Switzerland | 318 | 2026-10-01 | 2026-08-19 |
| Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars DIT112, DIPYRONE, TRAMADOL - Moderate Pain, Severe Pain | Phase 3 | Not yet recruiting | EMS | 252 | 2025-02-15 | 2024-02-20 |
| Fixed Dose Combination of COdeine + DIpyrone to Mitigate Moderate to Intense Pain Post-impacted Third Lower Molar Extraction FDC of codeine 30 mg/dipyrone 500 mg, Tylex - Pain | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 288 | 2023-11-08 | 2026-10-26 |
| Fixed Combination of Dipyrone and Codeine for Controlling Pain After Pelvic-abdominal Surgery Fixed dose combination Dipyrone and Codeine, Dipyrone, Codeine - Pain, Postoperative | Phase 3 | Completed | Brazilian Clinical Research Institute | 491 | 2023-03-16 | 2026-05-11 |
| The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma Gabapentin, Metamizol, Tramadol - Chronic Pain Due to Trauma, Spinal Cord Injuries | Phase 3 | Withdrawn | Masaryk University | 2017-10-01 | 2019-03-07 | |
| Analgesia iv vs Epidural Analgesia vs Port-sites Infiltration After Laparoscopic Sleeve Gastrectomy Port-sites infiltration:Bupivacaine0.25%, Epidural analgesia:Levobupivacaine0,125%, Metamizole and Acetaminophen iv - Postoperative Pain | Phase 3 | Completed | Hospital General Universitario Elche | 147 | 2012-01-01 | 2016-01-25 |
| Paracetamol Toxicity in Septic Patients paracetamol, dypirone - Fever, Sepsis | Phase 3 | Suspended | Barzilai Medical Center | 80 | 2010-08-01 | 2011-03-02 |
| Optimal Analgesia in Acute Gastroenteritis Dipyrone, Papaverine - Gastroenteritis | Phase 3 | Terminated | Hadassah Medical Organization | 15 | 2010-06-01 | 2016-03-17 |
| Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache Metamizol, Acetylsalicylic acid (ASA), Metamizol placebo - Migraine Disorders | Phase 3 | Completed | Boehringer Ingelheim | 417 | 1998-10-01 | 2014-07-08 |
Pain (3) · Pain, Postoperative (2) · Agnosia (1) · Cancer Pain (1) · Emergencies (1) · Fever (1) · Gastroenteritis (1) · Migraine Disorders (1) · Sepsis (1) · Spinal Cord Injuries (1)
Barzilai Medical Center (1) · Boehringer Ingelheim (1) · Brazilian Clinical Research Institute (1) · EMS (1) · Eurofarma Laboratorios S.A. (1) · Hadassah Medical Organization (1) · Hospital General Universitario Elche (1) · Masaryk University (1) · University Hospital, Basel, Switzerland (1)
Brazil (2) · Israel (2) · Czechia (1) · Switzerland (1)
Albert Grinshpun (1) · Christopher Boehlke, Prof. Dr. (1) · Manuel Duran, MD, PhD (1) · Ruth Stanikowitz, MD (1)