6 completed, 3 unknown, 2 terminated, 1 suspended. 7 Phase 2, 4 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 3, Terminated 2, Unknown 2 |
| Phase 3 | 4 | Completed 2, Suspended 1, Unknown 1 |
| Not applicable | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus. clevudine (drug) - Hepatitis B | Phase 2 | Unknown | Triangle Pharmaceuticals | 30 | 2002-08-01 | 2005-06-24 |
| Once Daily Antiretroviral Therapy in HIV Infected Adults Treated With HAART emtricitabine, FTC (drug), didanosine, ddI (drug), efavirenz (drug) - HIV Infections | Phase 3 | Completed | ANRS, Emerging Infectious Diseases | 350 | 2001-04-01 | 2026-06-15 |
| A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs Efavirenz, Emtricitabine, Stavudine - HIV Infections | Phase 3 | Unknown | Triangle Pharmaceuticals | 2000-08-01 | 2005-06-24 | |
| A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs Abacavir sulfate, Efavirenz, Emtricitabine - HIV Infections | Phase 3 | Suspended | Triangle Pharmaceuticals | 1999-08-01 | 2005-06-24 | |
| Pilot Study on Once Daily FTC, ddI, Efavirenz Combination in Antiretroviral Naive HIV Infected Adults emtricitabine, FTC (drug), didanosine, ddI (drug), efavirenz (drug) - HIV Infections, Antiretroviral Naive | Phase 2 | Completed | ANRS, Emerging Infectious Diseases | 39 | 1999-02-01 | 2026-06-15 |
| A Study of MKC-442 in HIV-Positive Patients Emivirine - HIV Infections | Phase 2 | Completed | Triangle Pharmaceuticals | 2005-06-24 | ||
| The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors Emivirine, Hydroxyurea, Delavirdine mesylate - HIV Infections | Phase 2 | Terminated | Bristol-Myers Squibb | 25 | 2008-08-14 | |
| Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV Lopinavir/Ritonavir, Emtricitabine, Stavudine - HIV Infections | Phase 2 | Unknown | Triangle Pharmaceuticals | 100 | 2005-06-24 | |
| A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive Emivirine, Nelfinavir mesylate - HIV Infections | Not applicable | Completed | Triangle Pharmaceuticals | 2005-06-24 | ||
| A Study of MKC-442 in Combination With Other Anti-HIV Drugs Emivirine, Hydroxyurea, Stavudine - HIV Infections | Phase 2 | Completed | Triangle Pharmaceuticals | 2005-06-24 | ||
| The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined With MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors Emivirine, Hydroxyurea, Nevirapine - HIV Infections | Phase 2 | Terminated | Bristol-Myers Squibb | 25 | 2008-08-14 | |
| Comparing FTC and Lamivudine in HIV-Infected Patients on a Stable Anti-HIV Drug Combination Emtricitabine, Lamivudine - HIV Infections | Phase 3 | Completed | Triangle Pharmaceuticals | 390 | 2005-06-24 |
HIV Infections (11) · Hepatitis B (1)
Didanosine (6) · Emtricitabine (6) · Stavudine (6) · emivirine (5) · efavirenz (4) · Hydroxyurea (3) · Pharmaceutical Preparations (3) · Racivir (2) · Delavirdine (1) · Lamivudine (1) · Lopinavir (1) · Nelfinavir (1) · Nevirapine (1) · abacavir (1) · clevudine (1)
United States (9) · France (3) · Argentina (2) · Canada (2) · Mexico (2) · Puerto Rico (2) · Chile (1) · China (1) · Panama (1) · Singapore (1) · South Africa (1)
Genevieve Chene, MD, PhD (2) · Jean-Michel Molina, MD, PhD (2) · Charles van der Horst (1)