5 completed, 1 unknown. 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Unknown 1 |
Follow Dexpramipexole: new trials by email Literature Review of Dexpramipexole trials Research Report on Dexpramipexole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma Dexpramipexole, Placebo - Eosinophilic Asthma, Asthma | Phase 2 | Completed | Knopp Biosciences | 534 | 2019-08-15 | 2023-04-13 |
| Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia dexpramipexole - Chronic Sinusitis With Nasal Polyps and Eosinophilia | Phase 2 | Completed | Knopp Biosciences | 20 | 2014-08-01 | 2021-05-18 |
| Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome Dexpramipexole - Hypereosinophilic Syndrome | Phase 2 | Unknown | National Institute of Allergy and Infectious Diseases (NIAID) | 15 | 2014-03-14 | 2017-12-07 |
| Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease R-pramipexole - Alzheimer's Disease | Phase 2 | Completed | Virginia Commonwealth University | 20 | 2011-07-01 | 2021-10-12 |
| Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211) KNS-760704 - Amyotrophic Lateral Sclerosis | Phase 2 | Completed | Knopp Biosciences | 74 | 2009-07-01 | 2021-08-16 |
| Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) Placebo, Dexpramipexole 50 mg/day, Dexpramipexole 150 mg/day - Amyotrophic Lateral Sclerosis | Phase 2 | Completed | Knopp Biosciences | 194 | 2008-04-09 | 2021-07-08 |
Amyotrophic Lateral Sclerosis (2) · Asthma (2) · Eosinophilia (2) · Motor Neuron Disease (2) · Nervous System Diseases (2) · Alzheimer Disease (1) · Hypereosinophilic Syndrome (1) · Nasal Polyps (1) · Pulmonary Eosinophilia (1) · Rhinosinusitis (1) · Sinusitis (1)
Knopp Biosciences (4) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Virginia Commonwealth University (1)
United States (6)
Amy D Klion, M.D. (1) · James P. Bennett, MD, PhD (1) · Jeffrey M Burns, MD (1) · Merit Cudkowicz, M.D., MSc (1)