24 completed, 3 terminated, 3 withdrawn, 1 active not recruiting. 34 Phase 1, 23 Phase 2.
Follow Cryosurgery: new trials by email Literature Review of Cryosurgery trials Research Report on Cryosurgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers Cryoablation, Cryoablation combined with PD1 Inhibitor - Triple Negative Breast Cancer | Phase 1 / Phase 2 | Not yet recruiting | Texas Tech University Health Sciences Center | 36 | 2026-03-01 | 2025-09-09 |
| A Study of Pembrolizumab and Ablation (Cryoablation or Histotripsy) in People With Breast Cancer Pembrolizumab, Cryoablation, Histotripsy - Metastatic Breast Cancer, Breast Cancer | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 30 | 2024-01-29 | 2026-09-14 |
| Cryotherapy for Locally Advanced Esophageal Cancer Cryotherapy - Esophageal Cancer | Phase 1 | Active not recruiting | Hunter Holmes Mcguire Veteran Affairs Medical Center | 14 | 2020-02-11 | 2026-09-18 |
| Cryoablation Combined With Camrelizumab and Apatinib for Multiprimary Lung Cancer Camrelizumab and Apatinib - Lung Cancer | Phase 1 / Phase 2 | Unknown | ShiYue Li | 20 | 2019-12-01 | 2019-12-17 |
| Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma Cryosurgery, Pembrolizumab, Pheresis - Stage III Cutaneous Melanoma AJCC v7, Stage IIIA Cutaneous Melanoma AJCC v7 | Phase 1 / Phase 2 | Terminated | Mayo Clinic | 7 | 2017-11-15 | 2025-06-12 |
| Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma Cryosurgery, Dendritic Cell Therapy, Laboratory Biomarker Analysis - Aggressive Non-Hodgkin Lymphoma, Indolent Non-Hodgkin Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 11 | 2017-08-15 | 2026-05-04 |
| Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas Pembrolizumab Injection [Keytruda], Cryoablation, Nephrectomy - Renal Cell Carcinoma, Metastatic Kidney Cancer | Phase 1 | Withdrawn | University of California, Irvine | 2017-07-01 | 2021-04-05 | |
| Safety and Efficiency of γδ T Cell Against Breast Cancer Cryosurgery , IRE surgery ,surgery, γδ T cells, γδ T cells/ Surgery - Breast Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 100 | 2017-06-15 | 2020-07-13 |
| Safety and Efficiency of γδ T Cell Against Lung Cancer Cryosurgery or IRE surgery, γδ T cell, γδ T cells/ A Cryosurgery or IRE - Lung Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2017-06-15 | 2020-07-13 |
| Safety and Efficiency of γδ T Cell Against Liver Cancer Cryosurgery or IRE surgery, γδ T cell, γδ T cells/ A Cryosurgery or IRE - Liver Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2017-06-15 | 2020-07-13 |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Liver Cancer Cryosurgery, NK Immunotherapy - Secondary Malignant Neoplasm of Liver | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Kidney Cancer Cryosurgery, NK immunotherapy - Metastatic Renal Cell Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer Cryosurgery, NK immunotherapy - Metastatic Esophageal Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 60 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgey and NK Immunotherapy for Recurrent Tongue Cancer Cryosurgery, NK immunotherapy - Recurrent Tongue Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Breast Cancer Cryosurgery, NK immunotherapy - Breast Cancer Recurrent | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 60 | 2016-07-01 | 2019-09-12 |
| Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma Cryoablation, Lidocaine, Saline - Intermetatarsal Neuroma | Phase 1 | Completed | Icahn School of Medicine at Mount Sinai | 10 | 2016-07-01 | 2018-11-06 |
| Combination of Cryosurgey and NK Immunotherapy for Recurrent Ovarian Cancer Cryosurgery, NK immunotherapy - Recurrent Ovarian Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgery and NK Immunotherapy for Advanced Non-Small Cell Lung Cancer Cryosurgery, NK Immunotherapy - Non-small Cell Lung Cancer Metastatic | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgey and NK Immunotherapy for Recurrent Pharyngeal Cancer Cryosurgery, NK immunotherapy - Recurrent Pharyngeal Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Combination of Cryosurgey and NK Immunotherapy for Recurrent Cervical Cancer Cryosurgery, NK immunotherapy - Recurrent Cervical Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
Showing 20 of 34. Sign in to see all of them.
Breast Neoplasms (7) · Liver Neoplasms (4) · Carcinoma, Renal Cell (3) · Melanoma (3) · Pain (3) · Sarcoma (3) · Bone Neoplasms (2) · Carcinoma, Hepatocellular (2) · Carcinoma, Non-Small-Cell Lung (2) · Esophageal Neoplasms (2) · Kidney Neoplasms (2) · Lung Neoplasms (2) · Neoplasm Metastasis (2) · Ovarian Neoplasms (2) · Triple Negative Breast Neoplasms (2)
Fuda Cancer Hospital, Guangzhou (16) · Boston Scientific Corporation (3) · Mayo Clinic (3) · Memorial Sloan Kettering Cancer Center (2) · Hunter Holmes Mcguire Veteran Affairs Medical Center (1) · Icahn School of Medicine at Mount Sinai (1) · Jonsson Comprehensive Cancer Center (1) · Michael Har-Noy (1) · Mirror Biologics, Inc. (1) · National Cancer Institute (NCI) (1) · ShiYue Li (1) · Texas Tech University Health Sciences Center (1) · University of California, Irvine (1) · University of Southern California (1)
China (16) · United States (14) · Canada (1) · France (1) · Israel (1)
Jibing Chen, MD, PhD (7) · Guifeng Liu, PhD (3) · Jibing Chen, PhD (3) · Jerry Matteo, MD (2) · David D Childs, MD (1) · David Spinner, DO (1) · Dr. Michael Har-Noy (1) · Heather McArthur, MD, MPH (1) · Helena R. Chang, MD, PhD (1) · Jaime Landman, MD (1) · Lawrence Menendez, MD (1) · Lizhi Niu, PhD (1) · Matthew S. Block, M.D., Ph.D. (1) · Svetomir N Markovic, MD, PhD (1) · Tamar Peretz, MD (1)
PMID 18054441, PMID 18565579, PMID 18834631, PMID 21123824, PMID 22075702, PMID 27816492, PMID 28508945, PMID 28679643, PMID 28923358, PMID 30578687, PMID 30688989
P30CA015083 (1), P50CA097274 (1), R01CA219960 (1)