9 completed, 2 not yet recruiting, 2 unknown, 1 suspended. 16 Phase 1, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 9, Not yet recruiting 2, Unknown 2, Suspended 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 8 | Completed 3, Unknown 2, Not yet recruiting 1, Suspended 1, Withdrawn 1 |
Follow Corticosteroid: new trials by email Literature Review of Corticosteroid trials Research Report on Corticosteroid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Asciminib-Based Induction Therapy for the Treatment of Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Asciminib, Biospecimen Collection, Blinatumomab - B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 1 | Not yet recruiting | City of Hope Medical Center | 21 | 2027-10-13 | 2026-11-03 |
| A Clinical Trial of MK-2750 in Participants With Advanced Solid Tumors (MK-2750-002) MK-2750, 5-HT3 serotonin receptor antagonist, NK-1 receptor antagonist - Advanced Solid Tumors, Malignant Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 300 | 2026-11-16 | 2026-10-15 |
| Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases Azeliragon, Stereotactic radiosurgery, Corticosteroid - Cancer, Metastasis | Phase 1 / Phase 2 | Suspended | Baptist Health South Florida | 46 | 2023-11-17 | 2026-06-16 |
| Mesenchymal Stem Cell Therapy for Knee Osteoarthritis Bone Marrow Derived MSCs, Corticosteroid, Bone Marrow Aspirate - Osteoarthritis, Knee | Phase 1 / Phase 2 | Unknown | Next Generation Regenerative Medicine LLC | 120 | 2022-08-01 | 2022-03-21 |
| Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial, Spirometry, RNA Sequencing - Sarcoidosis, Pulmonary, Sarcoidosis Lung | Phase 1 | Completed | Oregon Health and Science University | 5 | 2019-05-15 | 2022-02-18 |
| Safety and Tolerability of ISX (Isoxsuprine HCL) in MS Relapses Isoxsuprine Hydrochloride, Placebo, Corticosteroid - Multiple Sclerosis | Phase 1 / Phase 2 | Completed | University of New Mexico | 2 | 2019-02-15 | 2024-02-06 |
| Tolerance by Engaging Antigen During Cellular Homeostasis Donor-derived Mesenchymal Stromal Cells, alemtuzumab, belatacept - Kidney Transplantation, Renal Transplantation | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2018-07-30 | 2026-10-29 |
| Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects Itacitinib, Corticosteroid - Acute Graft-versus-host Disease | Phase 1 | Completed | Incyte Corporation | 14 | 2018-03-20 | 2020-03-03 |
| Induction Therapy for Multiple Myeloma With Carfilzomib, Lenalidomide,Dexamethasone,Panobinostat Panobinostat, Carfilzomib, Lenalidomide - Multiple Myeloma | Phase 1 / Phase 2 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2017-06-01 | 2017-04-25 | |
| A Study of Durvalumab in Combination With Lenalidomide With and Without Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Durvalumab, Lenalidomide, Dexamethasone - Multiple Myeloma | Phase 1 / Phase 2 | Completed | Celgene | 56 | 2016-04-25 | 2023-10-06 |
| Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis triamcinolone acetonide (Triesence®) - Uveitis, Intermediate Uveitis | Phase 1 / Phase 2 | Completed | Clearside Biomedical, Inc. | 11 | 2013-02-01 | 2021-02-21 |
| Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears Platelet Rich Plasma (PRP), Corticosteroid - Rotator Cuff Tear | Phase 1 | Terminated | University of North Carolina, Chapel Hill | 12 | 2012-11-01 | 2017-04-17 |
| A Study to Determine Safety & Efficacy of Autologous Human Platelet Lysate in Lateral Epicondylitis (Tennis Elbow) Autologous Human Platelet Lysate, Corticosteroid - Lateral Epicondylitis (Tennis Elbow) | Phase 1 / Phase 2 | Unknown | Kasiak Research Pvt. Ltd. | 20 | 2012-03-01 | 2012-08-20 |
| A Phase I Study of MK-2206 in Combination With Standard Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors (MK-2206-003) MK-2206, docetaxel, erlotinib - Locally Advanced, Metastatic Solid Tumors | Phase 1 | Completed | Merck Sharp & Dohme LLC | 77 | 2009-03-17 | 2019-11-12 |
| Rapamycin in Relapsed Acute Lymphoblastic Leukemia Corticosteroid, Rapamycin - Acute Lymphoblastic Leukemia | Phase 1 | Completed | Dana-Farber Cancer Institute | 6 | 2007-07-01 | 2016-11-23 |
| Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular Degeneration Corticosteroid - Choroidal Neovascularization, Macular Degeneration | Phase 1 | Completed | National Eye Institute (NEI) | 180 | 1997-07-01 | 2008-03-04 |
Neoplasms (3) · Multiple Myeloma (2) · Brain Neoplasms (1) · Choroidal Effusions (1) · Choroidal Neovascularization (1) · Giant Cell Arteritis (1) · Inflammation (1) · Macular Degeneration (1) · Multiple Sclerosis (1) · Neoplasm Metastasis (1) · Ophthalmia, Sympathetic (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Panuveitis (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Merck Sharp & Dohme LLC (2) · Baptist Health South Florida (1) · Celgene (1) · City of Hope Medical Center (1) · Clearside Biomedical, Inc. (1) · Dana-Farber Cancer Institute (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Incyte Corporation (1) · Kasiak Research Pvt. Ltd. (1) · National Eye Institute (NEI) (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Next Generation Regenerative Medicine LLC (1) · Oregon Health and Science University (1) · University of New Mexico (1) · University of North Carolina, Chapel Hill (1)
United States (11) · Canada (1) · Denmark (1) · Finland (1) · Germany (1) · India (1) · Italy (1) · Japan (1) · Netherlands (1) · Spain (1)
Allan D. Kirk, M.D., Ph.D. (1) · Anant Joshi, Dr. (1) · Berkoff David, MD (1) · Brendan C Mackinnon-Patterson, BS, MPH, MD (1) · Corey C Ford, M.D., Ph.D. (1) · Gauresh Palekar, Dr. (1) · James G Unnerstall (1) · Jim Rosenbaum, MD (1) · Lewis Silverman, MD (1) · Melissa Alsina, M.D. (1) · Michael A Scarpone, D.O. (1) · Minesh Mehta, M.D. (1) · Nicolas Antao, Dr. (1)
PMID 24387695, PMID 27980877, PMID 33825964
2015 (1), 2025 (1), P30CA033572 (1), UM1AI109565 (1)