21 recruiting. 21 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Recruiting 21 |
| Phase 2 | 3 | Recruiting 3 |
Follow Control: new trials by email Literature Review of Control trials Research Report on Control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ACT-GLOBAL IA Thrombolysis(ACT-REACT-004)Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632 Tenecteplase or Alteplase- depending upon availability at each treating centre, Control - Stroke, Acute Ischemic, Endovascular Thrombectomy | Phase 3 | Recruiting | University of Calgary | 1500 | 2026-08-11 | 2026-10-21 |
| Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma 10% urea lotion plus 1% cannabidiol, Control - Mediciine, Systemic Sclerosis (SSc) | Phase 3 | Recruiting | Khon Kaen University | 36 | 2025-11-05 | 2025-11-24 |
| Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome APC-0101 (SF-RI 1 surfactant for inhalation combined with a dedicated delivery system), Control - Respiratory Distress Syndrome, Pre-term Infants | Phase 3 | Recruiting | Aerogen Pharma Limited | 520 | 2025-09-24 | 2026-10-13 |
| Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY) 0.05% atropine eye drops, 0.025% atropine eye drops, placebo eye drops - Myopia | Phase 3 | Recruiting | Ocus Innovation Ireland Limited | 234 | 2025-09-01 | 2026-02-11 |
| A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients CAR T cells, Control - Gastric Adenocarcinoma | Phase 3 | Recruiting | Suzhou Immunofoco Biotechnology Co., Ltd | 150 | 2025-08-06 | 2025-10-23 |
| The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium Sleep Hygiene, Brain Game, and IV Acetaminophen Intervention, Control - Delirium, Postoperative, Delirium in Old Age | Phase 3 | Recruiting | Beth Israel Deaconess Medical Center | 406 | 2025-06-06 | 2026-04-15 |
| Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar PvSeroTAT, Control - Malaria Vivax, Malaria Falciparum | Phase 3 | Recruiting | London School of Hygiene and Tropical Medicine | 19200 | 2025-05-12 | 2026-09-18 |
| Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery Colchicine, Placebo - Cardiovascular Diseases, Cardiovascular Complication | Phase 3 | Recruiting | Cantonal Hospital of St. Gallen | 880 | 2025-04-20 | 2025-04-24 |
| Normobaric Oxygen in AIS Transferred for EVT NBO, Control - Ischemic Stroke | Phase 3 | Recruiting | Capital Medical University | 1500 | 2024-12-13 | 2025-12-11 |
| Efficacy of INM004 in Children With STEC-HUS INM004, Placebo - Hemolytic-Uremic Syndrome | Phase 3 | Recruiting | Inmunova S.A. | 220 | 2024-10-05 | 2026-01-15 |
| The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients Intervention 1, Intervention 2, Control - Delirium | Phase 2 / Phase 3 | Recruiting | Sultan Qaboos University | 240 | 2024-09-30 | 2025-01-14 |
| Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus GIE Medical ProTractX3 TTS DCB, Control - Esophageal Stricture | Phase 3 | Recruiting | GIE Medical | 198 | 2023-12-01 | 2025-06-25 |
| Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel GIE Medical ProTractX3 TTS DCB, Control - Bowel; Stricture | Phase 3 | Recruiting | GIE Medical | 171 | 2023-11-01 | 2025-06-25 |
| Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies Bone marrow aspirate concentrate (BMAC), Control - Acetabular Labrum Tear, Femoro Acetabular Impingement | Phase 3 | Recruiting | Massachusetts General Hospital | 160 | 2023-08-30 | 2024-11-20 |
| A Phase 3 Clinical Study of QLM3004 in Delaying Myopia in Children QLM3004 Concentration 1, QLM3004 Concentration 2, QLM3004 Concentration 3 - Myopia | Phase 3 | Recruiting | Qilu Pharmaceutical Co., Ltd. | 735 | 2023-08-20 | 2023-11-30 |
| Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies 0.9% saline solution, Povidone-iodine Swab - Surgical Site Infection, Surgical Wound | Phase 2 / Phase 3 | Recruiting | Dow University of Health Sciences | 200 | 2023-04-29 | 2025-06-18 |
| Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders PostbiotiX Comfort®, Control - Autism, Autism Disorder | Phase 2 / Phase 3 | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 90 | 2023-03-21 | 2026-03-04 |
| Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD) Metformin XR, Control - Autosomal Dominant Polycystic Kidney Disease | Phase 3 | Recruiting | The University of Queensland | 1174 | 2022-11-29 | 2026-03-31 |
| Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour Metformin hydrochloride (HCl) 500mg tablet, Placebo - Medulloblastoma, Childhood, Cognitive Impairment | Phase 3 | Recruiting | Donald Mabbott | 140 | 2022-07-01 | 2026-09-24 |
| BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases Surgical intervention, Control - Breast Cancer, Liver Metastases | Phase 3 | Recruiting | Umeå University | 200 | 2020-01-01 | 2022-05-25 |
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Delirium (2) · Ischemic Stroke (2) · Myopia (2) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · Breast Neoplasms (1) · Cardiovascular Diseases (1) · Cognitive Dysfunction (1) · Color Vision Defects (1) · Constriction, Pathologic (1) · Emergence Delirium (1) · Esophageal Stenosis (1) · Eye Diseases (1) · Femoracetabular Impingement (1) · Hemolytic-Uremic Syndrome (1)
GIE Medical (2) · Aerogen Pharma Limited (1) · Beth Israel Deaconess Medical Center (1) · Cantonal Hospital of St. Gallen (1) · Capital Medical University (1) · Donald Mabbott (1) · Dow University of Health Sciences (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Hadassah Medical Organization (1) · Inmunova S.A. (1) · Khon Kaen University (1) · London School of Hygiene and Tropical Medicine (1) · Massachusetts General Hospital (1) · Ocus Innovation Ireland Limited (1) · Qilu Pharmaceutical Co., Ltd. (1)
United States (5) · United Kingdom (4) · Australia (3) · Canada (3) · China (3) · Italy (3) · Spain (2) · Albania (1) · Argentina (1) · Belgium (1) · Ethiopia (1) · France (1) · Germany (1) · Ireland (1) · Israel (1)
Andrew Mallett, MBBS, PhD (1) · Annegret Dahlmann-Noor, PhD (1) · Bijoy K Menon, MD (1) · Chris Drakeley (1) · Craig Anderson, MD (1) · Donald Mabbott, Ph.D. (1) · Eric Bouffet, M.D. (1) · Fitsum G Tadesse (1) · Ian CK Wong, Professor (1) · Imrana Zulfikar, Professor (1) · Michael T White (1) · Omer Bin Khalid, Assist Prof. (1) · Oskar Hemmingsson, MD, PhD (1) · Rindra Randremanana (1) · Santiago Sanguineti, Ph.D (1)
PMID 38837240, PMID 39356039, PMID 40000080, PMID 40855441, PMID 41348481, PMID 41385299, PMID 41592826
2023 (1)