16 completed, 1 terminated, 1 unknown, 1 withdrawn. 10 Not applicable, 6 Phase 2, 5 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 9, Terminated 1 |
| Phase 2 | 6 | Completed 5, Withdrawn 1 |
| Phase 3 | 5 | Completed 4, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Cinnamon: new trials by email Literature Review of Cinnamon trials Research Report on Cinnamon
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes Cinnamon, Placebo - PreDiabetes, Blood Glucose, High | Not applicable | Completed | University of California, Los Angeles | 20 | 2021-04-14 | 2023-05-06 |
| Effectiveness of Cinnamon on Insulin Resistance ( ECIRCCOS ) December 1, 2019 Cinnamon - Obesity, Childhood, Insulin Resistance | Not applicable | Completed | Coordinación de Investigación en Salud, Mexico | 100 | 2019-11-12 | 2025-02-27 |
| Spices, Inflammation and Vascular Response in Humans Italian Herb meal, Cinnamon Meal, Pumpkin Spice meal - Healthy | Not applicable | Completed | Clinical Nutrition Research Center, Illinois Institute of Technology | 28 | 2019-04-18 | 2021-07-27 |
| In-vivo Effects of E-cigarette Aerosol on Innate Lung Host Defense Cinnamaldehyde e-liquid, PG/VG e-liquid - Smoking, Healthy | Not applicable | Terminated | University of North Carolina, Chapel Hill | 19 | 2018-10-19 | 2021-06-10 |
| Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua Cinnamon, Wheat Flour - Type 2 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Universidad Dr. José Matías Delgado | 30 | 2018-03-01 | 2020-11-09 |
| Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses cinnamon - Normal Weight, Overweight and Obesity | Not applicable | Completed | University of California, Los Angeles | 32 | 2018-01-01 | 2020-12-28 |
| Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes Cinnamon, placebo - Dysglycemia, Obesity | Phase 2 | Completed | Joslin Diabetes Center | 12 | 2017-08-28 | 2019-08-19 |
| Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans Cinnamon, Ginger, Chlorhexidine Gluconate - Dental Caries | Phase 3 | Unknown | Cairo University | 21 | 2017-03-01 | 2017-02-23 |
| The Effect of Cinnamon Cassia on Diabetes Control and Cardiometabolic Risk Factors in Adults With Type 2 Diabetes Mellitus Cinnamon, placebo - Diabetes Mellitus | Phase 2 | Withdrawn | Oregon Health and Science University | 2017-01-01 | 2019-08-06 | |
| Culinary Spices in Metabolic Syndrome. Ginger, black seed, cinnamon - Metabolic Syndrome | Not applicable | Completed | United Arab Emirates University | 120 | 2015-05-10 | 2025-03-30 |
| Effect of Over-the-counter Dietary Supplements on Kidney Stone Risk Aloe vera with cactus, Cranberry, Green tea extract - Hyperoxaluria | Not applicable | Completed | University of Wisconsin, Madison | 45 | 2015-02-01 | 2016-10-27 |
| Bioavailability Study of Cinnamon in Healthy Subjects cinnamon, Oatmeal - Healthy Males | Phase 1 / Phase 2 | Completed | McCormick and Company, Inc. | 8 | 2013-01-01 | 2020-03-06 |
| Effect of Oral Cinnamon Intervention in Metabolic Syndrome Cinnamon, Placebo - Metabolic Syndrome | Not applicable | Completed | Diabetes Foundation, India | 103 | 2011-08-01 | 2015-05-29 |
| Impact of Spices and Herbs on Endothelial Function Cinnamon, Oregano, Ginger - Endothelial Function | Not applicable | Completed | Laval University | 224 | 2010-03-01 | 2012-06-28 |
| The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses. Cinnamon, Placebo control - Gastric Emptying, Diabetes Mellitus | Not applicable | Completed | University of Limerick | 9 | 2009-06-01 | 2011-05-09 |
| Naturopathic Treatment for the Prevention of Cardiovascular Disease Naturopathic medicine. May include: fish oil, plant sterols, soluble fiber, cinnamon, coQ10 and exercise, Conventional medical treatment (Atorvastatin,Fluvastatin,Lovastatin,Pravastatin,Rosuvastatin,Simvastatin) - Cardiovascular Disease | Phase 3 | Completed | The Canadian College of Naturopathic Medicine | 300 | 2008-04-01 | 2010-05-17 |
| Is There a Metabolic Effect of Cinnamon on HbA1c, Blood Pressure and Serum Lipids in Type 2 Diabetes Mellitus? cinnamon 2g per day for 12 weeks - Type 2 Diabetes Mellitus | Phase 2 | Completed | Thames Valley University | 58 | 2008-03-01 | 2011-11-14 |
| Randomized Controlled Clinical Trial of Cinnamon to Lower Hemoglobin A1c cinnamon - Diabetes | Phase 3 | Completed | Eglin AFB Regional Hospital | 109 | 2007-03-01 | 2019-02-07 |
| The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes cinnamon - Type 1 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Dartmouth-Hitchcock Medical Center | 72 | 2005-10-01 | 2006-09-04 |
Diabetes Mellitus (3) · Diabetes Mellitus, Type 2 (2) · Insulin Resistance (2) · Metabolic Syndrome (2) · Obesity (2) · Cardiovascular Diseases (1) · Coronary Disease (1) · Dental Caries (1) · Diabetes Mellitus, Type 1 (1) · Glucose Intolerance (1) · Hyperoxaluria (1) · Overweight (1) · Pediatric Obesity (1) · Prediabetic State (1) · Smoking (1)
University of California, Los Angeles (2) · Cairo University (1) · Clinical Nutrition Research Center, Illinois Institute of Technology (1) · Coordinación de Investigación en Salud, Mexico (1) · Dartmouth-Hitchcock Medical Center (1) · Diabetes Foundation, India (1) · Eglin AFB Regional Hospital (1) · Joslin Diabetes Center (1) · Laval University (1) · McCormick and Company, Inc. (1) · Oregon Health and Science University (1) · Thames Valley University (1) · The Canadian College of Naturopathic Medicine (1) · United Arab Emirates University (1) · Universidad Dr. José Matías Delgado (1)
United States (9) · Canada (2) · Egypt (1) · El Salvador (1) · India (1) · Ireland (1) · Mexico (1) · United Arab Emirates (1) · United Kingdom (1)
Amalia Tsiami, PhD,MSc,BSc (1) · Amir Shafat, PhD (1) · Ana E Centeno, M.D. (1) · Britt Burton-Freeman, Ph.D (1) · Charles Couillard, Ph.D (1) · Dugald Seely, ND (1) · Giulio R Romeo, MD (1) · Heba Hamza, PhD (1) · Ilona Jaspers, PhD (1) · Jessie Nallelly Zurita Cruz (1) · Karla M Navarrete, M.D., MPh. (1) · Kevin Maki, PhD (1) · Kristina L Penniston, PhD, RD (1) · Mai Mamdouh, PhD (1) · Melissa V Abarca, M.D. (1)
PMID 18276664, PMID 19734396, PMID 20042780, PMID 20644701, PMID 21899741, PMID 23630244, PMID 24292639, PMID 24451612, PMID 24513588, PMID 24876603, PMID 25591663, PMID 26347778, PMID 26758574, PMID 28497094, PMID 28539866, PMID 28606084, PMID 28885566, PMID 29222377, PMID 29605574, PMID 33553233, PMID 35273988, PMID 37310415, PMID 38290699, PMID 38687136
R01HL139369 (1)