26 completed, 9 unknown, 2 recruiting, 2 terminated. 41 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 41 | Completed 26, Unknown 9, Recruiting 2, Terminated 2, Enrolling by invitation 1, Withdrawn 1 |
Follow Cefazolin: new trials by email Literature Review of Cefazolin trials Research Report on Cefazolin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Duration of Perioperative Antibiotics in Pancreatoduodenectomy single dose preoperative antibiotic, Prolonged perioperative antibiotics - Pancreatoduodenectomy, PPPD | Not applicable | Enrolling by invitation | Asan Medical Center | 558 | 2026-05-11 | 2026-05-28 |
| Prophylaxis Against Surgical Site Infections Using Local as Well as Systemic Antibiotic Cefazolin plus Gentamicin, Cefazolin - Surgical Site Infection (SSI) | Not applicable | Completed | Lahore General Hospital | 284 | 2025-07-01 | 2026-03-18 |
| Antibiotic Prophylaxis in Metabolic Bariatric Surgery 2000 mg of Cefazolin, 500 mg of Metronidazole IV, NACL 0.9% 100 ml - Antibiotic Reaction, Wound Infection Superficial | Not applicable | Unknown | General Committee of Teaching Hospitals and Institutes, Egypt | 3352 | 2024-10-01 | 2024-07-31 |
| Preoperative Daptomycin Prophylaxis in Two-Stage Exchange Arthroplasty: A Prospective, Randomized, Double-Blinded Trial Cefazolin with Daptomycin, Cefazolin with vancomycin - Periprosthetic Joint Infection | Not applicable | Unknown | Chang Gung Memorial Hospital | 184 | 2024-08-01 | 2024-01-05 |
| Randomized Assessment of Antibiotic Prophylaxis Prior to Port Placement Cefazolin, saline - Vascular Access Ports | Not applicable | Withdrawn | Dartmouth-Hitchcock Medical Center | 2024-01-01 | 2024-04-26 | |
| Prophylactic Antibiotics in Groin Hernioplasty Cefazolin - Surgical Site Infection, Groin Hernia | Not applicable | Completed | Sana'a University | 100 | 2023-10-01 | 2025-08-13 |
| Comparing of Cefazolin Plus Azithromycin Versus Cefazolin in Prevention of Febrile Morbidity After Emergency Cesarean Delivery Azithromycin Injection [Zithromax], Cefazolin, Sodium Chloride 0.9% Intravenous Solution - Febrile Morbidity After Emergency Cesarean Section | Not applicable | Completed | Department of Medical Services Ministry of Public Health of Thailand | 172 | 2022-12-14 | 2024-01-25 |
| Bowel Preparation in Elective Pediatric Colorectal Surgery Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral - Colostomy, Hirschsprung Disease - Pull Through | Not applicable | Unknown | McMaster University | 81 | 2022-01-01 | 2021-12-09 |
| Prophylactic Antibiotic After Perineal Tear Cefazolin (Cefamezin) - Puerperal Infection | Not applicable | Unknown | Meir Medical Center | 2500 | 2021-03-01 | 2021-02-23 |
| Supracondylar Pinning Antibiotic Stewardship (SPAS) Trial Cefazolin, normal saline - Supracondylar Humerus Fracture, Infection | Not applicable | Unknown | Legacy Health System | 1200 | 2021-01-07 | 2022-04-12 |
| Single Dose Versus 24 Hours Antibiotic Prophylaxis in Reduction Mammaplasty Cephazolin, Sterile saline - Plastic Surgery, Mammaplasty | Not applicable | Completed | Daniela Francescato Veiga | 146 | 2019-08-04 | 2025-02-26 |
| Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome Cefazolin - Microbial Colonization, Antibiotic Side Effect | Not applicable | Completed | University Medical Center Groningen | 33 | 2019-03-01 | 2023-09-13 |
| Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia Cloxacillin, Cefazolin - Bacteremia Due to Methicillin Susceptible Staphylococcus Aureus | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 315 | 2018-09-05 | 2025-11-24 |
| Application of Intra-operative Prophylactic Antibiotics/Antiseptics in Chinese Breast Reconstruction Patients Cefazolin/clindamycin - Breast Neoplasms | Not applicable | Unknown | Tianjin Medical University Cancer Institute and Hospital | 291 | 2018-06-16 | 2018-11-15 |
| Does a Preoperative Prophylactic Antibiotic Reduce Surgical Site Infection Following Wire-localized Lumpectomy Cefazolin Injection - Breast Cancer | Not applicable | Completed | CHU de Quebec-Universite Laval | 326 | 2018-04-07 | 2021-03-29 |
| Antibiotic Prophylaxis in Clean Surgery. Impact on Surgical Site Infection Cefazolin, Placebos - Surgical Site Infection | Not applicable | Completed | University of Rwanda | 138 | 2018-03-01 | 2019-09-04 |
| Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery Cefazolin, Ceftriaxone - Propionibacterium Infection | Not applicable | Recruiting | Université de Montréal | 88 | 2016-12-01 | 2026-05-01 |
| Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem - Pharmacokinetics, Amoxicillin-clavulanate | Not applicable | Recruiting | University Hospital, Ghent | 300 | 2016-08-19 | 2026-09-21 |
| The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin, Appendectomy - Appendicitis | Not applicable | Completed | University of Washington | 1552 | 2016-05-01 | 2023-05-06 |
| Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation Chlorhexidine irrigation, triple antibiotic irrigation - Breast Cancer | Not applicable | Completed | Vanderbilt University Medical Center | 88 | 2015-12-01 | 2022-01-26 |
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Surgical Wound Infection (7) · Breast Neoplasms (4) · Wound Infection (4) · Infections (3) · Appendicitis (2) · Fractures, Closed (2) · Bacteremia (1) · Communicable Diseases (1) · Dentofacial Deformities (1) · Endometritis (1) · Enterocolitis, Necrotizing (1) · Hernia, Inguinal (1) · Inflammatory Bowel Diseases (1) · Intestinal Obstruction (1) · Meconium Ileus (1)
HaEmek Medical Center, Israel (2) · Asan Medical Center (1) · Assistance Publique - Hôpitaux de Paris (1) · Atlantic Center for Oral and Maxillofacial Surgery (1) · Brigham and Women's Hospital (1) · CHU de Quebec-Universite Laval (1) · Chang Gung Memorial Hospital (1) · Daniela Francescato Veiga (1) · Dartmouth-Hitchcock Medical Center (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Fabiola Soares Moreira Campos (1) · General Committee of Teaching Hospitals and Institutes, Egypt (1) · Hamilton Health Sciences Corporation (1) · Hormozgan University of Medical Sciences (1) · Ito Hospital (1)
United States (12) · Canada (5) · Brazil (4) · Netherlands (3) · Israel (2) · Belgium (1) · China (1) · Egypt (1) · France (1) · Iran (1) · Japan (1) · Pakistan (1) · Rwanda (1) · South Korea (1) · Taiwan (1)
Daniela F Veiga, MD, PhD (2) · Alexandra Zhernakova, MD/PhD (1) · Allison Rao, MD (1) · Annick de Jaeger, MD (1) · Bob Umberhandt, MD (1) · Brenna Anderson, MD (1) · Brett D Crist, MD (1) · Dan Hershko, Professor (1) · David A Talan, MD (1) · David R Flum, MD, MPH (1) · Dominik Mertz, MD, MSc (1) · Dominique Rouleau, MD (1) · Eli N. Perencevich, MD MS BS (1)
PMID 10219875, PMID 10998650, PMID 12841893, PMID 18839083, PMID 20934625, PMID 21126927, PMID 23325435, PMID 23461695, PMID 24807330, PMID 25376070, PMID 25932849, PMID 27412673, PMID 28505360, PMID 29146633, PMID 30173161, PMID 30558680, PMID 31236724, PMID 31737738, PMID 31993070, PMID 33416442, PMID 33618788, PMID 34825283, PMID 35612859, PMID 35796152, PMID 35815898, PMID 36197656, PMID 36336720, PMID 36925849, PMID 37148398, PMID 37379001, PMID 37471087, PMID 38796500, PMID 40857697, PMID 41115439