51 completed, 3 active not recruiting, 3 recruiting, 2 terminated. 59 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 59 | Completed 51, Active not recruiting 3, Recruiting 3, Terminated 2 |
Follow Carbamazepine: new trials by email Literature Review of Carbamazepine trials Research Report on Carbamazepine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Verducatib in the Blood Verducatib, Carbamazepine - Healthy | Phase 1 | Recruiting | Boehringer Ingelheim | 20 | 2026-09-10 | 2026-09-23 |
| A Trial of Lu AH69593 in Healthy Participants Lu AH69593, Itraconazole, Carbamazepine - Healthy Participants | Phase 1 | Recruiting | H. Lundbeck A/S | 46 | 2026-08-27 | 2026-10-14 |
| A Study to Evaluate the Effect of Carbamazepine or Itraconazole on Radiprodil in Healthy Adult Participants Radiprodil, Carbamazepine, Itraconazole (200 mg) - Healthy Adult Participants | Phase 1 | Active not recruiting | GRIN Therapeutics, Inc. | 36 | 2026-06-08 | 2026-10-21 |
| Drug-Drug Interaction Study of Atumelnant in Healthy Participants Atumelnant, Carbamazepine, Midazolam - Healthy Volunteers | Phase 1 | Completed | Crinetics Pharmaceuticals Inc. | 46 | 2026-05-28 | 2026-08-19 |
| Drug-drug Interaction Trial of AP31969 and Carbamazepine or Itraconazole AP31969, Carbamazepine, Itraconazole - Healthy Participants | Phase 1 | Completed | Acesion Pharma | 28 | 2026-04-01 | 2026-05-22 |
| A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together Repinatrabit, EE/NE, Metformin - Healthy Volunteers | Phase 1 | Recruiting | Otsuka Pharmaceutical Development & Commercialization, Inc. | 48 | 2026-03-31 | 2026-08-12 |
| A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults Setidegrasib, Fluconazole, Carbamazepine - Healthy Volunteer | Phase 1 | Active not recruiting | Astellas Pharma Global Development, Inc. | 54 | 2026-02-03 | 2026-08-27 |
| To Assess the Enzyme Inducing Effects of Carbamazepine on the PK of Mirdametinib in Healthy Participants Mirdametinib, Mirdametinib and Carbamazepine - Healthy, Volunteer | Phase 1 | Completed | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany | 36 | 2025-12-15 | 2026-05-08 |
| A Study to Learn if Multiple Doses of the Study Medicine Called Carbamazepine Changes How the Body Processes the Other Study Medicine PF-07248144 PF-07248144, Carbamazepine - Healthy Adults | Phase 1 | Completed | Pfizer | 12 | 2025-09-18 | 2026-04-03 |
| A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Nerandomilast in the Blood nerandomilast, carbamazepine - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 16 | 2025-08-11 | 2025-10-14 |
| Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults Radiprodil with Carbamazepine, Radiprodil with Itraconazole - Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia | Phase 1 | Terminated | GRIN Therapeutics, Inc. | 30 | 2025-05-08 | 2025-11-21 |
| A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Carbamazepine on INCB123667 When Administered Orally to Healthy Adult Participants INCB123667, itraconazole, carbamazepine - Healthy Participants | Phase 1 | Completed | Incyte Corporation | 51 | 2025-05-05 | 2026-06-15 |
| Drug-Drug Interaction Potential of Mavorixafor Mavorixafor, Carbamazepine, Efavirenz - Healthy Participants | Phase 1 | Completed | X4 Pharmaceuticals | 38 | 2025-02-18 | 2025-07-01 |
| A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323. EDP-323, Itraconazole, carbamazepine - RSV Infection, Drug Drug Interaction (DDI) | Phase 1 | Completed | Enanta Pharmaceuticals, Inc | 48 | 2025-01-27 | 2025-07-01 |
| A Multi-part Study of ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Drug-drug Interaction Potential After Single and Multiple Doses in Healthy Volunteers Carbamazepine, Itraconazole (Sporanox), ALG-000184 - Healthy Volunteer | Phase 1 | Active not recruiting | Aligos Therapeutics | 24 | 2025-01-09 | 2025-02-03 |
| A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012) Opevesostat, Prednisone, Fludrocortisone acetate - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 14 | 2024-12-18 | 2025-05-25 |
| A Drug-drug Interaction Study of S-892216 Coadministered With Carbamazepime to Healthy Adult Participants S-892216, Carbamazepine - COVID-19 | Phase 1 | Completed | Shionogi | 16 | 2024-12-17 | 2025-03-11 |
| Drug-Drug Interaction Study of Bomedemstat and Carbamazepine in Healthy Adult Participants (MK-3543-020) bomedemstat, carbamazepine - Healthy | Phase 1 | Completed | Merck Sharp & Dohme LLC | 16 | 2024-10-02 | 2025-03-18 |
| An Open-label Study in Healthy Participants to Evaluate AZD0780 as an Object or Precipitant of CYP3A4-mediated Drug-drug Interactions AZD0780, Itraconazole, Carbamazepine - Dyslipidaemia | Phase 1 | Completed | AstraZeneca | 59 | 2024-09-25 | 2025-04-27 |
| A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants Midazolam, Camizestrant, Carbamazepine - Healthy Participants | Phase 1 | Completed | AstraZeneca | 40 | 2024-08-27 | 2025-09-04 |
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Boehringer Ingelheim (4) · Eli Lilly and Company (4) · Cerevel Therapeutics, LLC (3) · Enanta Pharmaceuticals, Inc (3) · Pfizer (3) · Alexion Pharmaceuticals, Inc. (2) · Aligos Therapeutics (2) · AstraZeneca (2) · Bayer (2) · DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company (2) · Dizal Pharmaceuticals (2) · GRIN Therapeutics, Inc. (2) · Hoffmann-La Roche (2) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (2)
United States (34) · Germany (6) · Belgium (4) · United Kingdom (3) · Australia (2) · Canada (2) · France (2) · Netherlands (1) · Uruguay (1)
Francisco E. Estevez-Carrizo, M.D. (1) · Francisco T. Estevez-Parrillo, M.D. (1)
PMID 25912051, PMID 27517350, PMID 40679917, PMID 41703907, PMID 9812178
2025 (2), 2019 (1), 2023 (1)