18 completed, 9 recruiting, 3 active not recruiting, 3 unknown. 27 Not applicable, 6 Phase 2, 2 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow Bright Light Therapy: new trials by email Literature Review of Bright Light Therapy trials Research Report on Bright Light Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Circadian-Optimized Light Therapy for the Treatment of Patients With Advanced Melanoma Receiving Tumor-Infiltrating Lymphocyte Therapy Biospecimen Collection, Internet-Based Intervention, Medical Device Usage and Evaluation - Advanced Cutaneous Melanoma, Clinical Stage III Cutaneous Melanoma AJCC v8 | Phase 1 | Not yet recruiting | City of Hope Medical Center | 8 | 2026-12-23 | 2026-06-05 |
| reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit Sleep chronobundle, Control - Sleep, Circadian Dysregulation | Early Phase 1 | Not yet recruiting | University of Alberta | 50 | 2026-11-30 | 2026-10-21 |
| Bright Light Therapy in Patients With Melanoma or Non-small Cell Lung Cancer (NSCLC) Who Are Receiving First-Line Immune Checkpoint Blockade Bright Light Therapy - Melanoma (Skin Cancer), NSCLC (Non-small Cell Lung Cancer) | Not applicable | Recruiting | Weill Medical College of Cornell University | 12 | 2026-10-03 | 2026-09-23 |
| Bright Light Therapy for Depressed Geriatric Inpatients Bright light therapy, dim red light - Unipolar Depression | Phase 2 | Enrolling by invitation | Medical University of South Carolina | 20 | 2025-11-14 | 2026-04-16 |
| Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness Bright light therapy, Dim red light - Depression, Unipolar | Not applicable | Recruiting | Chinese University of Hong Kong | 90 | 2025-11-01 | 2026-03-19 |
| Effect of Bright Light Therapy on Idiopathic Scoliosis Bright Light Therapy, Sleep Hygiene Education - Idiopathic Scoliosis, Eveningness | Not applicable | Recruiting | Second Affiliated Hospital of Wenzhou Medical University | 120 | 2025-09-01 | 2026-05-19 |
| Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy Bright White Light Therapy, Combination Drug Therapy, Electronic Health Record Review - Advanced Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 210 | 2024-07-09 | 2026-10-07 |
| BioClock: Bright Light Therapy for Depressive Disorders Bright Light Therapy, Blue Light Blocking Glasses - Depression, Unipolar, Depression, Bipolar | Not applicable | Recruiting | Universiteit Leiden | 231 | 2024-02-08 | 2025-01-09 |
| Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype Cognitive Behavioural Therapy for Depression, Bright Light Therapy - Depression, Unipolar, Eveningness | Not applicable | Recruiting | The University of Hong Kong | 162 | 2023-10-31 | 2024-04-22 |
| Implementation of Bright Light Therapy ID Bright light therapy - Depressive Symptoms | Recruiting | Erasmus Medical Center | 105 | 2023-10-18 | 2025-09-25 | |
| Impact of Bright Light Therapy on Prader-Willi Syndrome Sham Light, Bright Light Therapy - Prader-Willi Syndrome, Excessive Daytime Sleepiness | Not applicable | Active not recruiting | Maimonides Medical Center | 50 | 2023-10-01 | 2026-10-06 |
| A Feasibility Trial for Circadian Rest-activity Rhythm Disorders in Cancer (RALI) Cognitive behavioural therapy for Insomnia (CBT-I), Bright Light Therapy, Individualised activity plan - Circadian Rhythm Disorders, Cancer | Not applicable | Completed | University of Dublin, Trinity College | 30 | 2023-06-01 | 2025-04-03 |
| Bright Light Therapy for Post-COVID-19 Fatigue Bright light therapy, Dim red light therapy - Post COVID-19 Condition | Not applicable | Completed | Chinese University of Hong Kong | 12 | 2023-02-15 | 2026-03-20 |
| Cognitive Behavioral Therapy and Light Therapy CBT-I, Bright Light Therapy - Pulmonary Hypertension, Insomnia | Not applicable | Completed | University of Pennsylvania | 6 | 2023-01-12 | 2025-01-27 |
| Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers Best Practice, Bright White Light Therapy, Occupational Therapy - Bladder Carcinoma, Genitourinary System Neoplasm | Not applicable | Recruiting | City of Hope Medical Center | 224 | 2023-01-11 | 2026-10-19 |
| Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease Bright light therapy, Inactivated negative ion generator - Parkinson Disease | Not applicable | Completed | Chinese University of Hong Kong | 69 | 2022-12-09 | 2026-03-20 |
| A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis Bright Light Therapy, Placebo Retimer Device - Inflammatory Bowel Disease | Not applicable | Recruiting | Rush University Medical Center | 30 | 2022-09-22 | 2026-06-09 |
| Adjunctive Bright Light Therapy in Patients With Bipolar Depression and Eveningness Bright light therapy, Inactive negative ion generator - Bipolar Depression | Not applicable | Active not recruiting | Chinese University of Hong Kong | 70 | 2022-06-02 | 2026-03-05 |
| A Wearable Morning Light Treatment for Postpartum Depression Bright Light Therapy, Dim Light Therapy - Post Partum Depression | Not applicable | Completed | University of Michigan | 95 | 2021-06-23 | 2026-09-02 |
| Using Early Time Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults With Type 2 Diabetes No change in meal timing, No change in light exposure, Early Time-Restricted Feeding - Diabetes Mellitus, Type 2, Time Restricted Feeding | Not applicable | Completed | University of Alabama at Birmingham | 190 | 2021-04-26 | 2026-06-02 |
Showing 20 of 38. Sign in to see all of them.
Depression (12) · Fatigue (8) · Depressive Disorder (5) · Bipolar Disorder (3) · Chronobiology Disorders (3) · Disorders of Excessive Somnolence (3) · Neoplasms (3) · Sleep Initiation and Maintenance Disorders (3) · Anxiety Disorders (2) · Behavior (2) · Delirium (2) · Depression, Postpartum (2) · Melanoma (2) · Motor Activity (2) · Obesity (2)
Chinese University of Hong Kong (4) · City of Hope Medical Center (3) · M.D. Anderson Cancer Center (2) · Medical University of Vienna (2) · CHU de Quebec-Universite Laval (1) · Erasmus Medical Center (1) · Geestelijke Gezondheidszorg Eindhoven (GGzE) (1) · Goethe University (1) · Hospital Authority, Hong Kong (1) · Inha University Hospital (1) · Istanbul University - Cerrahpasa (1) · Maimonides Medical Center (1) · Massachusetts General Hospital (1) · Medical University of South Carolina (1) · Peking University (1)
United States (14) · Hong Kong (6) · Canada (4) · Netherlands (4) · Austria (2) · China (2) · Spain (2) · Finland (1) · Germany (1) · Ireland (1) · South Korea (1) · Turkey (Türkiye) (1) · United Kingdom (1)
William Dale (2) · Ali Keshavarzian, M.D. (1) · Cana Aksoy Poyraz, MD (1) · Carlos Fernandez-Robles, MD (1) · Christine M Freitag, Prof. Dr. (1) · Colin M. Shapiro, MBBCh, PhD (1) · Courtney Peterson, Ph.D. (1) · Edward Yi, MD (1) · Garth R Swanson, M.D. (1) · Heng Joshua Tang (1) · Kelly Mahuron (1) · Kristina M Deligiannidis, MD (1) · Lea Ann A Matura, PhD (1)
PMID 25182079, PMID 29053981, PMID 29172605, PMID 29482662, PMID 31264101, PMID 31924662, PMID 34442202, PMID 34581703, PMID 38627266, PMID 40120538, PMID 41088238, PMID 42594524
P30CA033572 (3), R01MH121531 (1), R25DA020537 (1)