9 recruiting, 5 active not recruiting, 2 completed, 2 terminated. 20 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Recruiting 9, Active not recruiting 5, Completed 2, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
Follow Best Practice: new trials by email Literature Review of Best Practice trials Research Report on Best Practice
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia Best Practice, Biospecimen Collection, Cytarabine - Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia | Phase 3 | Recruiting | Children's Oncology Group | 556 | 2026-08-14 | 2026-09-04 |
| Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy Educational Intervention, Health Telemonitoring, Questionnaire Administration - Hematologic Malignancies | Phase 3 | Recruiting | City of Hope Medical Center | 380 | 2026-01-14 | 2026-08-28 |
| Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity Standard of Care Chemotherapy, Biospecimen Collection, Computed Tomography - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 2 / Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 148 | 2025-10-24 | 2026-10-05 |
| Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy Autologous Hematopoietic Stem Cell Transplantation, Best Practice, Biospecimen Collection - Anaplastic Large Cell Lymphoma, ALK-Negative, Follicular Helper T-Cell Lymphoma | Phase 3 | Recruiting | Eastern Cooperative Oncology Group | 294 | 2025-06-18 | 2026-09-14 |
| Comparing Radiation Therapy to Usual Treatment for Patients With High-Risk Bone Metastases That Are Not Causing Pain, PREEMPT Trial Best Practice, Biospecimen Collection, Bone Metastases Treatment - Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm | Phase 3 | Active not recruiting | NRG Oncology | 280 | 2025-05-07 | 2026-08-17 |
| Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer Best Practice, Biospecimen Collection, Electronic Health Record Review - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 3 | Recruiting | Children's Oncology Group | 60 | 2025-02-27 | 2026-08-31 |
| Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial Stereotactic Ablative Radiotherapy, Best Practice - Oligometastasis, Lung Cancer | Phase 3 | Recruiting | Roswell Park Cancer Institute | 800 | 2024-09-18 | 2026-02-04 |
| Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial Best Practice, Comprehensive Geriatric Assessment, Educational Intervention - Lymphoma, Malignant Solid Neoplasm | Phase 3 | Recruiting | University of Rochester | 668 | 2023-03-21 | 2026-01-13 |
| Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy Best Practice, Wound Dressing Material, Quality-of-Life Assessment - Breast Carcinoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 216 | 2022-07-26 | 2026-09-23 |
| Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy Educational Intervention, Text Message-based Navigation Intervention, Motivational Interviewing - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 1167 | 2021-02-15 | 2026-10-19 |
| Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant Best Practice and Internet site with links to existing resources, Internet, Mobile app and Telehealth Intervention, Survey Administration - Hematopoietic and Lymphoid Cell Neoplasm | Phase 3 | Completed | Fred Hutchinson Cancer Center | 546 | 2020-10-29 | 2025-01-29 |
| Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 Best Practice, Low Dose Radiation Therapy - Pneumonia, Severe Acute Respiratory Syndrome | Phase 3 | Unknown | Emory University | 14 | 2020-06-23 | 2023-08-14 |
| Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection) Best Practice, Tocilizumab - Cerebrovascular Accident, Chronic Obstructive Pulmonary Disease | Phase 3 | Withdrawn | Emory University | 2020-04-07 | 2020-06-18 | |
| Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors Best Practice, Entecavir, Tenofovir Alafenamide - Hepatitis B Infection, Malignant Solid Neoplasm | Phase 3 | Terminated | SWOG Cancer Research Network | 4 | 2020-01-17 | 2024-05-20 |
| Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases Supportive Palliative Care, Clinical Management, Best Practice - Hematopoietic and Lymphoid Cell Neoplasm, Non-Neoplastic Hematologic and Lymphocytic Disorder | Phase 2 / Phase 3 | Terminated | Fred Hutchinson Cancer Center | 458 | 2019-08-15 | 2026-01-12 |
| Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial Best Practice, Biospecimen Collection, Computed Tomography - Pathologic Stage I Cutaneous Merkel Cell Carcinoma AJCC v8, Pathologic Stage II Cutaneous Merkel Cell Carcinoma AJCC v8 | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 280 | 2018-11-15 | 2026-10-26 |
| Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy Best Practice, Computed Tomography, Gallium Ga 68-labeled PSMA-11 - Recurrent Prostate Carcinoma | Phase 3 | Active not recruiting | Jonsson Comprehensive Cancer Center | 193 | 2018-07-12 | 2026-05-26 |
| Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer Vaginal Cuff Brachytherapy, Short course vaginal cuff brachytherapy - Endometrial Clear Cell Adenocarcinoma, Endometrial Endometrioid Adenocarcinoma | Phase 3 | Recruiting | University of Utah | 188 | 2018-02-02 | 2025-12-12 |
| Decision Aids in Improving Knowledge in Patients With Newly Diagnosed Prostate Cancer Internet-Based Intervention, Best Practice, Quality-of-Life Assessment - Stage II Prostate Cancer, Stage IIA Prostate Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 158 | 2017-10-02 | 2025-01-27 |
| Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Best Practice, Biopsy Procedure, Biospecimen Collection - Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma | Phase 3 | Recruiting | Children's Oncology Group | 1780 | 2017-05-25 | 2026-08-25 |
Hematologic Neoplasms (3) · Prostatic Neoplasms (3) · COVID-19 (2) · Breast Neoplasms (1) · Carcinoma, Embryonal (1) · Colonic Neoplasms (1) · Coronary Artery Disease (1) · Cytokine Release Syndrome (1) · Diabetes Mellitus (1) · Endodermal Sinus Tumor (1) · Hepatitis B (1) · Kidney Failure, Chronic (1) · Leukemia, Myeloid, Acute (1) · Lung Neoplasms (1) · Lymphoma (1)
Alliance for Clinical Trials in Oncology (3) · Children's Oncology Group (3) · Emory University (2) · Fred Hutchinson Cancer Center (2) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1) · Eastern Cooperative Oncology Group (1) · Jonsson Comprehensive Cancer Center (1) · NRG Oncology (1) · National Cancer Institute (NCI) (1) · Roswell Park Cancer Institute (1) · SWOG Cancer Research Network (1) · University of Rochester (1) · University of Utah (1)
United States (20) · Canada (3) · Australia (1) · Guam (1) · India (1) · Japan (1) · Mexico (1) · New Zealand (1) · Puerto Rico (1) · Saudi Arabia (1) · United Kingdom (1)
A. L Frazier (1) · Ajay K Nooka (1) · Anurag Singh, MD (1) · Cristina DeCesaris, MD (1) · Eric J Chow (1) · Erin F Gillespie (1) · Janice Mehnert (1) · Jennifer J Wilkes (1) · Jeremie Calais (1) · Jessica P Hwang (1) · K. Scott Baker (1) · Katherine E. Reeder-Hayes, MD (1) · Kimberly Corbin, MD (1) · Maheswari Senthil (1) · Mohamed Sorror, MD, MSc (1)
PMID 30081846, PMID 30616601, PMID 33386288, PMID 34890060, PMID 35292232, PMID 37783480, PMID 37828596, PMID 41698328, PMID 41825136
U10CA180820 (3), P30CA138292 (2), UG1CA189823 (2), UG1CA189955 (2), R01CA215134 (1), R01CA227092 (1), R01CA237357 (1), R01CA249467 (1), U10CA180886 (1), U24CA196173 (1), UG1CA189867 (1), UG1CA189961 (1), UG1CA189974 (1)