4 completed, 2 unknown, 1 enrolling by invitation. 7 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Unknown 2, Enrolling by invitation 1 |
| Phase 2 | 3 | Completed 2, Enrolling by invitation 1 |
Follow Berberine: new trials by email Literature Review of Berberine trials Research Report on Berberine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of Berberine Berberine, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Enrolling by invitation | The University of Hong Kong | 100 | 2024-08-01 | 2025-01-20 |
| Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis Carvedilol, Berberine - Cirrhosis Due to Hepatitis B, Cirrhosis Due to Hepatitis C | Phase 3 | Unknown | Tianjin Second People's Hospital | 288 | 2021-11-01 | 2021-10-25 |
| Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. Berberine, Placebo - Metabolic Syndrome, HIV-1-infection | Phase 3 | Unknown | Hospital Civil de Guadalajara | 40 | 2021-04-01 | 2021-04-26 |
| A Mechanistic Randomized Controlled Trial on the Cardiovascular Effect of Berberine Berberine, Placebo - Cardiovascular Risk Factor | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 84 | 2019-04-01 | 2020-11-04 |
| Berberine as Adjuvant Treatment for Schizophrenia Patients Berberine, Placebos, Antipsychotic Agents - Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 113 | 2018-04-25 | 2021-01-22 |
| Bezafibrate Plus Berberine in Mixed Dyslipidemia Berberine, Bezafibrate, Berberine plus Bezafibrate - Mixed Dyslipidemia | Phase 3 | Completed | University of Guadalajara | 36 | 2013-04-01 | 2023-02-24 |
| Efficacy and Safety of Berberine in the Treatment of Diabetes With Dyslipidemia Berberine - Diabetes Mellitus, Type 2, Metabolic Syndrome | Phase 3 | Completed | Shanghai Jiao Tong University School of Medicine | 120 | 2005-04-01 | 2007-04-18 |
Metabolic Syndrome (3) · Dyslipidemias (2) · Diabetes Mellitus, Type 2 (1) · Fibrosis (1) · Glucose Intolerance (1) · Hyperlipidemias (1) · Hypertension, Portal (1) · Lipodystrophy (1) · Schizophrenia (1) · Schizophrenia Spectrum and Other Psychotic Disorders (1)
The University of Hong Kong (3) · Hospital Civil de Guadalajara (1) · Shanghai Jiao Tong University School of Medicine (1) · Tianjin Second People's Hospital (1) · University of Guadalajara (1)
Hong Kong (3) · China (1) · Mexico (1)
Jie Zhao, Dr (1) · Jie Zhao, PhD (1) · Xiao-Ying Li, MD,PhD (1)
PMID 11211893, PMID 11303974, PMID 14571769, PMID 15349904, PMID 15753544, PMID 19610055, PMID 20558165, PMID 22666844, PMID 22863002, PMID 23250049, PMID 23262249, PMID 23323248, PMID 23333527, PMID 23601333, PMID 23607641, PMID 24291366, PMID 25309085, PMID 25339809, PMID 25447847, PMID 25643846, PMID 25820757, PMID 26047908, PMID 26174047, PMID 26192220, PMID 26327764, PMID 26629816, PMID 26945557, PMID 27222411, PMID 27298379, PMID 27694143, PMID 28403947, PMID 29113028, PMID 29492989, PMID 29650333, PMID 29942096, PMID 30125369, PMID 31210717, PMID 3192160, PMID 31926918, PMID 3262200, PMID 37611246, PMID 41882153, PMID 9581672