4 completed, 3 unknown, 1 enrolling by invitation, 1 terminated. 9 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 4, Unknown 3, Enrolling by invitation 1, Terminated 1 |
| Phase 3 | 3 | Completed 2, Enrolling by invitation 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow Berberine: new trials by email Literature Review of Berberine trials Research Report on Berberine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of Berberine Berberine, Placebo - Hyperlipidemia | Phase 2 / Phase 3 | Enrolling by invitation | The University of Hong Kong | 100 | 2024-08-01 | 2025-01-20 |
| Effect of Berberine for Endothelial Function and Intestinal Microflora in Patients With Coronary Artery Disease Berberine, Aspirin, Clopidogrel - Stable Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 1 / Phase 2 | Unknown | Peking Union Medical College Hospital | 24 | 2019-06-21 | 2020-06-16 |
| A Mechanistic Randomized Controlled Trial on the Cardiovascular Effect of Berberine Berberine, Placebo - Cardiovascular Risk Factor | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 84 | 2019-04-01 | 2020-11-04 |
| Gefitinib and Berberine in the First-line Treatment of Lung Adenocarcinoma With EGFR Mutation gefitinib, Berberine - Lung Adenocarcinoma, EGFR Mutation | Phase 2 | Unknown | Fujian Cancer Hospital | 50 | 2018-06-05 | 2018-04-03 |
| Berberine as Adjuvant Treatment for Schizophrenia Patients Berberine, Placebos, Antipsychotic Agents - Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 113 | 2018-04-25 | 2021-01-22 |
| Efficacy and Safety of Berberine in Non-alcoholic Steatohepatitis Lifestyle intervention, Placebo, Berberine - Non-alcoholic Steatohepatitis | Phase 2 | Terminated | Fudan University | 89 | 2017-08-16 | 2026-09-23 |
| Combination of Danazole With Berberine in the Treatment of ITP Berberine plus danazol - Corticosteroid-resistant or Relapsed ITP | Phase 2 | Unknown | Peking University People's Hospital | 55 | 2016-01-20 | 2020-09-25 |
| Role of Pioglitazone and Berberine in Treatment of Non-Alcoholic Fatty Liver Disease Life style intervention, pioglitazone, berberine - Nonalcoholic Fatty Liver Disease | Phase 2 | Completed | Xin Gao | 184 | 2008-03-01 | 2012-06-05 |
| Therapeutic Effects of Berberine in Patients With Type 2 Diabetes Berberine, Metformin - Type 2 Diabetes | Phase 1 / Phase 2 | Completed | Shanghai Jiao Tong University School of Medicine | 70 | 2004-01-01 | 2007-01-22 |
Non-alcoholic Fatty Liver Disease (2) · Adenocarcinoma of Lung (1) · Diabetes Mellitus, Type 2 (1) · Hyperlipidemias (1) · Metabolic Syndrome (1) · Purpura, Thrombocytopenic, Idiopathic (1) · Schizophrenia (1) · Schizophrenia Spectrum and Other Psychotic Disorders (1)
The University of Hong Kong (3) · Fudan University (1) · Fujian Cancer Hospital (1) · Peking Union Medical College Hospital (1) · Peking University People's Hospital (1) · Shanghai Jiao Tong University School of Medicine (1) · Xin Gao (1)
China (6) · Hong Kong (3)
Cheng Huang, MD. (1) · Jie Zhao, Dr (1) · Jie Zhao, PhD (1) · Jun Yin, MD, PhD (1) · Ran Tian, M.D. (1) · Xiaohui Zhang, MD (1) · Xin Gao (1)
PMID 26252777, PMID 27629750, PMID 28665143, PMID 33210751, PMID 33397443, PMID 41882153