benazepril: Clinical Trials

46 trials of benazepril, newest first

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35 completed, 5 terminated, 3 unknown, 1 active not recruiting. 13 Phase 1, 12 Phase 4, 7 Not applicable, 7 Phase 2, 7 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 113Completed 12, Unknown 1
Phase 412Completed 10, Enrolling by invitation 1, Suspended 1
Not applicable7Completed 4, Terminated 3
Phase 27Unknown 3, Completed 2, Active not recruiting 1, Terminated 1
Phase 37Completed 6, Terminated 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes
Phase 4Enrolling by invitationBaylor Research Institute642026-04-082026-10-13
Centrally Acting ACE Inhibition in SLE
Lisinopril Pills, Benazepril Pill - Systemic Lupus Erythematosus
Phase 2Active not recruitingNorthwell Health362021-10-012025-09-19
Study of Hydroxychloroquine in Patients With X-linked Alport Syndrome in China (CHXLAS)
Hydroxychloroquine Sulfate 100 milligram (mg) Tab, Benazepril hydrochloride 10 milligram (mg) Tab - Alport Syndrome, X-Linked
Phase 2CompletedShanghai Children's Hospital502021-09-082026-03-02
Coronavirus (COVID-19) ACEi/ARB Investigation
Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19
Phase 4SuspendedNational University of Ireland, Galway, Ireland24142020-04-302020-06-30
ACEI or ARB and COVID-19 Severity and Mortality in US Veterans
ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID
CompletedUniversity of Utah222132020-01-192021-04-28
The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in Children
Prednisone, ACEI - Henoch-Schoenlein Purpura Nephritis
Phase 2UnknownNanjing Children's Hospital1002015-08-012020-02-26
The Research of Standard Diagnosis and Treatment for HSPN in Children
Prednisone, Cyclophosphamide(CTX), Mycophenolate mofetil(MMF) - Henoch-Schoenlein Purpura Nephritis
Phase 2UnknownNanjing Children's Hospital1002015-08-012020-02-26
Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
ACEI continuation, ACEI omission - Hypotension on Induction
Phase 4CompletedUniversity of Nebraska2912015-06-012023-09-25
Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment
Glycosides Of Tripterygium Wilfordii Hook(GTW), Sulfotanshinone Sodium Injection, Chinese herbs based on syndrome differentiation - Henoch-Schönlein Purpura Nephritis
Phase 1 / Phase 2UnknownHenan University of Traditional Chinese Medicine5002014-09-012018-07-19
Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine
Benazepril, Losartan - Hypertension, Diabetes Mellitus
Phase 4CompletedHospital Universitario Pedro Ernesto302012-05-012016-02-01
Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors
lisinopril, losartan potassium, laboratory biomarker analysis - Hypertension, Unspecified Adult Solid Tumor, Protocol Specific
Phase 2TerminatedWake Forest University Health Sciences62011-02-012018-08-28
Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia
Placebo, Benazepril hydrochloride - Renal Alteration
Phase 3CompletedUniversity Hospital, Geneva1202010-04-012018-05-01
Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients
Benazepril, Valsartan, Benazepril+Valsartan - Renal Function Disorder
Not applicableCompletedSun Yat-sen University2002008-09-012015-05-20
Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency
Benazepril, Losartan, Benazepril+Losartan - Renal Insufficiency, Chronic
Not applicableTerminatedNanfang Hospital, Southern Medical University3092008-02-012016-04-05
ADDM Study - Amtrel and Co-Diovan in Type 2 Diabetes Mellitus Hypertension Patients With Microalbuminuria
Amlodipine+Benazepril, Valsartan+Hydrochlorothiazide - Hypertension, Diabetes Mellitus, Type 2
Phase 4CompletedTSH Biopharm Corporation Limited2262007-06-012011-06-17
Preventing ESRD in Overt Nephropathy of Type 2 Diabetes
Benazepril, Valsartan, Benazepril/Valsartan - Diabetes
Phase 3CompletedMario Negri Institute for Pharmacological Research1022007-05-012016-06-01
Preventing Microalbuminuria in Type 2 Diabetes
Benazepril, Valsartan, Benazepril/Valsartan - Diabetes
Phase 3CompletedMario Negri Institute for Pharmacological Research6122007-05-012019-09-06
Bioequivalence Study of Amlodipine Besylate/Benazepril HCl 10 mg/40 mg Capsules of Dr. Reddy's Under Fasting Conditions
Amlodipine Besylate/Benazepril HCl - Fasting
Phase 1CompletedDr. Reddy's Laboratories Limited502007-03-012012-01-09
Bioequivalence Study of Amlodipine Besylate/Benazepril HCl 10 mg/40 mg Capsules of Dr. Reddy's Under Fed Conditions
Amlodipine Besylate/Benazepril HCl - Fed
Phase 1CompletedDr. Reddy's Laboratories Limited492007-03-012012-01-09
Combination of Benazepril Plus Hydrochlorothiazide in Chinese Patients With Mild to Moderate Essential Hypertension
Benazepril plus hydrochlorothiazide - Hypertension
Phase 3CompletedNovartis2962006-07-012007-07-09

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Conditions studied

Hypertension (15)  ·  Diabetes Mellitus (6)  ·  Diabetes Mellitus, Type 2 (4)  ·  Albuminuria (3)  ·  Renal Insufficiency, Chronic (3)  ·  Cardiovascular Diseases (2)  ·  Nephritis, Hereditary (2)  ·  Proteinuria (2)  ·  Atherosclerosis (1)  ·  COVID-19 (1)  ·  Cardiomyopathy, Dilated (1)  ·  Coronary Disease (1)  ·  Coronavirus Infections (1)  ·  Diabetic Nephropathies (1)  ·  Disease Progression (1)

Sponsors

Novartis (6)  ·  Dr. Reddy's Laboratories Limited (4)  ·  Mylan Pharmaceuticals Inc (4)  ·  Teva Pharmaceuticals USA (4)  ·  Mario Negri Institute for Pharmacological Research (3)  ·  Nanjing Children's Hospital (2)  ·  Ranbaxy Laboratories Limited (2)  ·  Southern Medical University, China (2)  ·  Abbott (1)  ·  Baylor Research Institute (1)  ·  Charles Drew University of Medicine and Science (1)  ·  Daiichi Sankyo (1)  ·  Henan University of Traditional Chinese Medicine (1)  ·  Hospital Universitario Pedro Ernesto (1)  ·  Nanfang Hospital, Southern Medical University (1)

Countries

United States (21)  ·  China (9)  ·  Canada (3)  ·  Italy (3)  ·  India (2)  ·  Brazil (1)  ·  Denmark (1)  ·  Finland (1)  ·  Ireland (1)  ·  Norway (1)  ·  Slovenia (1)  ·  Sweden (1)  ·  Switzerland (1)  ·  Taiwan (1)

Top investigators

Fan Fan Hou, M.D.,Ph.D. (3)  ·  Aihua Zhang, M.D. (2)  ·  Dorian Williams, M.D. (2)  ·  Gaetano Morelli, M.D (2)  ·  I. S. Gandhi., MD (2)  ·  Richard Larouche, M.D. (2)  ·  Adam P Bress, PharmD, MS (1)  ·  Denise Simons-Morton, MD, PhD (1)  ·  Erica Daina, MD (1)  ·  Fei Xiong, M.D. (1)  ·  Giuseppe Remuzzi, MD (1)  ·  Hao Zhang, M.D. (1)

Results publications

PMID 36853224, PMID 16407508, PMID 18539917, PMID 18776118, PMID 19052124, PMID 19687350, PMID 19890370, PMID 19898642, PMID 20061358, PMID 20061360, PMID 20170948, PMID 20215456, PMID 20228401, PMID 20228404, PMID 20427682, PMID 20571135, PMID 20587587, PMID 20594588, PMID 20620720, PMID 21366473, PMID 21663644, PMID 21958949, PMID 22019270, PMID 22049171, PMID 22179956, PMID 22374637, PMID 22432114, PMID 22450889, PMID 22515638, PMID 22619083, PMID 22646230, PMID 22723577, PMID 22784975, PMID 23033246, PMID 23219284, PMID 23238658, PMID 23412077, PMID 23990163, PMID 24170759, PMID 24296848, PMID 24493100, PMID 24595629, PMID 24779562, PMID 25088437, PMID 25127725, PMID 25159234, PMID 25172198, PMID 25193529, PMID 25229335, PMID 25267796

NIH funding

N01HC95178 (1), N01HC95179 (1), N01HC95180 (1), N01HC95181 (1), N01HC95182 (1), N01HC95183 (1), N01HC95184 (1), U54RR014616 (1)