12 completed, 9 terminated, 3 unknown, 2 not yet recruiting. 21 Not applicable, 4 Phase 3, 2 Phase 2, 1 Phase 4.
Follow Autograft: new trials by email Literature Review of Autograft trials Research Report on Autograft
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Allograft vs. Autograft Nonunion Autograft, Allograft - Nonunion Fracture | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 156 | 2027-01-01 | 2026-10-26 |
| A Randomized Intra-Patient Controlled Trial of MagnetOs™ Putty vs Autograft in Instrumented Posterolateral Spinal Fusion in Idiopathic Scoliosis Patients MagnetOs putty 2.5cc, autograft - Adolescence Idiopathic Scoliosis | Not applicable | Not yet recruiting | UMC Utrecht | 140 | 2026-05-01 | 2026-04-06 |
| Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns Intact fish skin graft, autograft - Partial-thickness Burn Wounds | Phase 4 | Enrolling by invitation | Kerecis Ltd. | 65 | 2026-01-01 | 2026-01-08 |
| A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions. MagnetOs, Autograft - Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion | Not applicable | Recruiting | Kuros Biosurgery AG | 126 | 2025-11-25 | 2026-09-01 |
| Comparative Analysis of Virtuos and Autograft in Lumbar Fusion Virtuos - Degenerative Disc Disease | Not applicable | Terminated | Orthofix Inc. | 6 | 2022-11-14 | 2025-11-28 |
| Evaluation of Cranioplasty Using Native Bone Autograft Versus Synthetic Bone Allograft Synthetic Bone Allograft (ClearFit), Autograft - Surgical Procedure, Unspecified | Not applicable | Terminated | LifeBridge Health | 1 | 2021-02-10 | 2025-01-22 |
| COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES autograft, autograft with addition of concenterated growth factor, xenograft with concentrated growth factor - To Assess the Bone Healing in Fracture Mandible Defects | Phase 2 / Phase 3 | Unknown | Dow University of Health Sciences | 60 | 2020-12-17 | 2022-07-29 |
| Comparing Efficacy of Bone Marrow Aspirate Concentrate (BMAC) Combined With Allograft in Treatment of Calcaneus Fractures Autograft, Allograft only, Allograft combined with BMAC - Fractures, Bone | Not applicable | Withdrawn | University of Alabama at Birmingham | 2019-07-10 | 2023-08-01 | |
| BMAC & Allograft vs BMP-2 Bone Marrow Aspirate Concentrate (BMAC) + Allograft, Recombinant Human Bone Morphogenetic Protein-2 (BMP), Autograft - Spinal Fusion | Not applicable | Completed | NYU Langone Health | 59 | 2018-07-24 | 2025-07-08 |
| Indication to Transplant Patients With High Risk B Cells Lymphoma in Metabolic Complete Remission? Autograft - Lymphoma, B-Cell | Unknown | Institut Paoli-Calmettes | 183 | 2017-07-03 | 2018-09-24 | |
| StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements StrataGraft Skin Tissue, Autograft - Burn, Thermal | Phase 3 | Completed | Stratatech, a Mallinckrodt Company | 71 | 2017-05-30 | 2021-07-14 |
| StrataGraft® Skin Tissue as an Alternative to Autografting Full-thickness Complex Skin Defects StrataGraft Skin Tissue, Autograft - Trauma-related Wound, Burns | Phase 2 | Terminated | Stratatech, a Mallinckrodt Company | 3 | 2017-04-24 | 2021-08-03 |
| Computer Guided Versus Conventional Augmentation Using Bone Ring Computer Guided Stent Augmentation, Free Hand Augmentation, Platelet-rich fibrin (PRF) - Bone Resorption | Not applicable | Unknown | Cairo University | 10 | 2017-02-01 | 2017-02-09 |
| AttraX® Putty vs. Autograft in XLIF® AttraX Putty, Iliac Crest Bone Graft (ICBG) - Degenerative Conditions of the Lumbar Spine | Not applicable | Completed | NuVasive | 45 | 2014-12-01 | 2025-12-22 |
| NanOss Bioactive With Autograft and Bone Marrow Aspirate in the Posterolateral Spine nanOSS, Autograft - Lumbar Spinal Stenosis Secondary to Other Disease | Not applicable | Withdrawn | Pioneer Surgical Technology, Inc. | 2011-10-01 | 2017-01-04 | |
| INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine INFUSE Bone Graft, Iliac Crest Bone Graft - Lumbar Spine Degeneration | Phase 3 | Terminated | Medtronic Spinal and Biologics | 15 | 2011-07-01 | 2016-02-18 |
| Bone Graft Materials Observational Registry Bone graft substitute, autograft or allograft - Degenerative Disc Disease, Herniated Disc | Terminated | Baxter Healthcare Corporation | 329 | 2009-09-01 | 2017-04-05 | |
| Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute Bioactive glass, Beta-tricalcium phosphate (ChronOs), Autograft - Bone Neoplasm | Completed | Turku University Hospital | 120 | 2009-03-01 | 2021-03-16 | |
| INFUSE® Bone Graft and MASTERGRAFT® Granules With CD HORIZON® for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease - Pilot Study INFUSE® Bone Graft/MASTERGRAFT® Granules/CD HORIZON®, Autogenous Bone / CD HORIZON® Spinal System - Degenerative Disc Disease | Not applicable | Completed | Medtronic Spinal and Biologics | 46 | 2003-04-01 | 2023-05-17 |
| INFUSE ® Bone Graft/CORNERSTONE-SR® Allograft Ring/ATLANTIS® Anterior Cervical Plate System Pivotal Trial INFUSE™ Bone Graft/CORNERSTONE-SR™ /ATLANTIS™, Autogenous bone/CORNERSTONE-SR™ /ATLANTIS™ - Degenerative Cervical Disc Disease | Not applicable | Terminated | Medtronic Spinal and Biologics | 3 | 2002-04-01 | 2013-08-02 |
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Intervertebral Disc Degeneration (12) · Burns (4) · Intervertebral Disc Displacement (2) · Spinal Stenosis (2) · Spondylolisthesis (2) · Bone Neoplasms (1) · Bone Resorption (1) · Failed Back Surgery Syndrome (1) · Fractures, Bone (1) · Fractures, Ununited (1) · Ichthyosis Vulgaris (1) · Lymphoma, B-Cell (1) · Mandibular Fractures (1) · Radiculopathy (1) · Spinal Cord Neoplasms (1)
Medtronic Spinal and Biologics (12) · Stratatech, a Mallinckrodt Company (2) · Baxter Healthcare Corporation (1) · Cairo University (1) · Dow University of Health Sciences (1) · Institut Paoli-Calmettes (1) · Kerecis Ltd. (1) · Kuros Biosurgery AG (1) · LifeBridge Health (1) · NYU Langone Health (1) · NuVasive (1) · Orthofix Inc. (1) · Pioneer Surgical Technology, Inc. (1) · The University of Texas Medical Branch, Galveston (1) · Turku University Hospital (1)
United States (12) · Brazil (1) · Egypt (1) · Finland (1) · France (1) · Hungary (1) · Netherlands (1) · Pakistan (1)
Cristiano M Menezes, M.D. (1) · David N Herndon, MD (1) · Hannu T Aro, MD, PhD (1) · Huub Kreuwel, Ph.D (1) · John Dimar, MD (1) · Joseph R Hsu, MD (1) · Kenneth Burkus, MD (1) · Michael Johnson, MD (1) · Moyo Kruyt, PhD (1) · Peter Passias (1) · William Ashley, MD, PhD, MBA (1)