Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study

NCT06899672 — Not applicable, Not yet recruiting, 96 participants, Altamash Institute of Dental Medicine

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RegistryNCT06899672
StatusNot yet recruiting
PhaseNot applicable
Study typeInterventional; non randomized, parallel, masking: single, basic science
Enrollment96 (Estimated)
SponsorAltamash Institute of Dental Medicine (Other)
ConditionsDimensional Changes
InterventionsAlginate mixed with distilled water, 0.2% Chlorhexidine + Alginate, 1% Chitosan + Alginate, 0.2% Silver Nitrate + Alginate, Green-synthesized Silver Nanoparticles + Alginate, 15% Povidone-Iodine + Alginate (Other)
Datesstart 2025-04-01 (estimated), primary completion 2025-07-01 (estimated), completion 2025-10-01 (estimated), first posted 2025-03-28, last updated 2025-03-28

Related Papers Related Patents Related Grants Related Experts
All trials for Dimensional Changes All trials of Alginate mixed with distilled water All trials of 0.2% Chlorhexidine + Alginate

-Summary

This quasi-experimental comparative study investigates the effects of incorporating various self-disinfecting agents-0.2% Chlorhexidine (CHX), 1% Chitosan solution, 0.2% Silver Nitrate (AgNO3), green-synthesized Silver Nanoparticles (AgNPs), and 15% PVP-Iodine-on the linear dimensional stability of dental alginate impressions. Alginate is widely used in dentistry but is prone to dimensional changes and contamination. This study aims to assess whether integrating these disinfectants can reduce microbial risks without compromising the material's dimensional accuracy, thereby improving infection control and the precision of dental prostheses

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+Arms and interventions

ArmTypeInterventionsDescription
Control Group (Distilled Water)ExperimentalOther: Alginate mixed with distilled waterParticipants (specimens) will receive alginate mixed with distilled water without any disinfectant, serving as the baseline group
CHX Group (0.2% Chlorhexidine)ExperimentalOther: 0.2% Chlorhexidine + AlginateParticipants (specimens) will receive alginate mixed with 0.2% Chlorhexidine solution to assess its effect on dimensional stability
Chitosan Group (1% Chitosan)ExperimentalOther: 1% Chitosan + AlginateParticipants (specimens) will receive alginate mixed with 1% Chitosan solution to evaluate its effect on dimensional stability
Silver Nitrate Group (0.2% Silver Nitrate)ExperimentalOther: 0.2% Silver Nitrate + AlginateParticipants (specimens) will receive alginate mixed with 0.2% Silver Nitrate solution to evaluate its effect on dimensional stability
Silver Nanoparticles Group (Green-Synthesized AgNPs)ExperimentalOther: Green-synthesized Silver Nanoparticles + AlginateParticipants (specimens) will receive alginate mixed with green-synthesized silver nanoparticles to investigate its impact on dimensional stability
PVP-Iodine Group (15% Povidone-Iodine)ExperimentalOther: 15% Povidone-Iodine + AlginateParticipants (specimens) will receive alginate mixed with 15% Povidone-Iodine solution to determine its effect on dimensional stability
  • Alginate mixed with distilled water (Other): Alginate will be mixed with distilled water only, without any disinfectant additive, to serve as the control for comparison
  • 0.2% Chlorhexidine + Alginate (Other): Alginate will be mixed with 0.2% Chlorhexidine solution to evaluate its effect on the linear dimensional stability of alginate impressions
  • 1% Chitosan + Alginate (Other): Alginate will be mixed with 1% Chitosan solution to assess its influence on the linear dimensional stability of alginate impressions
  • 0.2% Silver Nitrate + Alginate (Other): Alginate will be mixed with 0.2% Silver Nitrate solution to determine its effect on the dimensional stability of alginate impressions
  • Green-synthesized Silver Nanoparticles + Alginate (Other): Alginate will be mixed with a solution of green-synthesized Silver Nanoparticles to investigate its effect on the dimensional stability of alginate impressions
  • 15% Povidone-Iodine + Alginate (Other): Alginate will be mixed with 15% Povidone-Iodine solution to analyze its influence on the dimensional stability of alginate impressions

+Outcome measures

Primary outcomes

  • Linear Dimensional Stability of Alginate Impressions [1 hour after impression making and cast pouring]: Measurement of the linear dimensional changes (in millimeters) of alginate impressions mixed with disinfectant additives compared to the control group.

+Eligibility

Sex: All, ages: 60 Minutes to any

Inclusion Criteria:

* Dental stone casts free from excessive porosity, fractures, or other visible defects that could affect dimensional stability measurements.
* Typodont models with intact maxillary arch configurations.

Exclusion Criteria:

* Distorted impressions, under-extended impressions, impressions that detach from the tray before pouring, and impressions with voids, on visual inspection.
* Dental cast with a fracture component, incomplete pouring, and those with voids or bubbles.