85 completed. 85 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 85 | Completed 85 |
Follow Urinary Bladder, Overactive: new trials by email Literature Review of Urinary Bladder, Overactive trials Research Report on Urinary Bladder, Overactive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vaginal Estrogen on Alterations in the Urine Microbiome of Menopausal Women With Overactive Bladder 17β-estradiol 10 mcg - Overactive Bladder (OAB), Menopause | Phase 4 | Completed | Mahidol University | 30 | 2025-06-27 | 2026-02-09 |
| Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women vaginal 17 beta-estradiol, Placebo, Behavioral modifications - Lower Urinary Tract Symptoms, Female Genitourinary Disease | Phase 4 | Completed | Mahidol University | 86 | 2024-04-08 | 2025-04-20 |
| Comparing Treatments for Refractory Overactive Bladder: Bladder Denervation vs Botulinum Toxin Injections Selective Bladder Denervation via Radiofrequency Ablation, Intravesical Onabotulinum Toxin A Injection - Overactive Bladder Syndrome, Refractory Overactive Bladder | Phase 4 | Completed | Bagcilar Training and Research Hospital | 60 | 2023-02-01 | 2025-02-19 |
| A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters Self-Administered Nitrous Oxide, Oxygen - Lower Urinary Tract Symptoms | Phase 4 | Completed | Beth Israel Deaconess Medical Center | 19 | 2023-01-10 | 2026-03-12 |
| Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection Single-Dose Antibiotic, Multi-Dose Antibiotic - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Completed | The Cleveland Clinic | 100 | 2022-12-06 | 2024-01-02 |
| Procedural Discomfort Related to Number of Intradetrusor Botox Injections Intradetrusor Botox Injections - Overactive Bladder | Phase 4 | Completed | The Methodist Hospital Research Institute | 108 | 2022-07-07 | 2025-04-13 |
| Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial OnabotulinumtoxinA 100 UNT [Botox] - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | University of California, Irvine | 116 | 2022-05-01 | 2026-02-25 |
| Darifenacin x Parasacral Transcutaneous Electric Nerve Stimulation for OAB in Patients Infected With Human T-Lymphotropic Virus 1 Darifenacin, Neuromodulation - Sacral nerve stimulation - HTLV-1, Overactive Bladder Syndrome | Phase 4 | Completed | Hospital Universitário Professor Edgard Santos | 42 | 2022-03-16 | 2024-10-01 |
| Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study) Mirabegron 50 MG, Posterior Tibial Nerve Stimulation (PTNS) - Overactive Bladder | Phase 4 | Completed | University of Alabama at Birmingham | 54 | 2021-10-01 | 2023-07-20 |
| A Study With Mirabegron 50 mg and 25 mg in Chinese Participants With Overactive Bladder mirabegron - Urge Incontinence, Overactive Bladder (OAB) | Phase 4 | Completed | Astellas Pharma China, Inc. | 249 | 2021-01-06 | 2024-11-15 |
| Minimizing Pain During Office Intradetrussor Botox Injection Bicarbonate protocol, Standard protocol - Overactive Bladder, Overactive Detrusor | Phase 4 | Completed | Boston Urogynecology Associates | 85 | 2020-08-15 | 2025-03-06 |
| Tolterodine Relieves Overactive Bladder Symptoms in Women With Moderate-to-severe Obstructive Sleep Apnea Syndrome Tolterodine Tartrate 4 MG, Continuous positive airway pressure therapy (CPAP) - Overactive Bladder, Obstructive Sleep Apnea | Phase 4 | Completed | Yuzuncu Yil University | 60 | 2020-06-01 | 2022-02-22 |
| Is 10 Injections of Bladder Botox Less Painful Than 20 Injections? OnabotulinumtoxinA 100 Units - Overactive Bladder | Phase 4 | Completed | Wake Forest University Health Sciences | 41 | 2019-11-10 | 2024-04-17 |
| Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder Anticholinergic, Beta-3 Agonists, Adrenergic, Functional magnetic resonance imaging (fMRI) - Overactive Bladder, Dementia | Phase 4 | Completed | Baylor Research Institute | 12 | 2019-08-05 | 2024-02-02 |
| Evaluation of Intradetrusor AbobotulinumtoxinA and IncobotulinumtoxinA in Women With Overactive Bladder AbobotulinumtoxinA 300 UNT, IncobotulinumtoxinA 100 UNT, Lidocain - Overactive Bladder | Phase 4 | Completed | Niko Kavcic | 64 | 2018-08-14 | 2024-02-12 |
| Lidocaine for Pain After Urodynamic Testing Lidocaine gel 2%, Standard lubricant gel - Voiding Disorders, Overactive Bladder | Phase 4 | Completed | Atlantic Health System | 134 | 2018-01-25 | 2019-07-19 |
| Efficacy and Safety of the Mirabegron Compared With Solifenacin in Treatment of Overactive Bladder Mirabegron 25mg, Solifenacin Succinate 5 MG - Overactive Bladder | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 81 | 2017-01-01 | 2018-06-19 |
| Evaluation of an Alternative Injection Paradigm for OnabotulinumtoxinA (BOTOX®) in the Treatment of Overactive Bladder in Patients With Urinary Incontinence onabotulinumtoxinA, Placebo (saline) - Urinary Bladder, Overactive, Urinary Incontinence | Phase 4 | Completed | Allergan | 120 | 2016-12-12 | 2019-12-24 |
| Investigation of the Effect of the Female Urinary Microbiome on Incontinence Estrogen Cream - Overactive Bladder, Incontinence | Phase 4 | Completed | Loyola University | 35 | 2016-09-01 | 2021-09-23 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH) Mirabegron, Placebo, Tamsulosin Hydrochloride - Benign Prostatic Hyperplasia, Overactive Bladder | Phase 4 | Completed | Astellas Pharma Global Development, Inc. | 715 | 2016-06-13 | 2024-11-12 |
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