2 completed, 1 not yet recruiting, 1 recruiting. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Not yet recruiting 1 |
Follow Tumor Infiltrating Lymphocytes: new trials by email Literature Review of Tumor Infiltrating Lymphocytes trials Research Report on Tumor Infiltrating Lymphocytes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on the Safety and Tolerability of PD-1 Knockout Tumor-infiltrating T Cells (TILs) in the Treatment of Advanced Colorectal Cancer transfusion of 5×10^8 PD-1 knockout TILs per kg body weight, transfusion of 1×10^9 PD-1 edited TILs per kg body weight, transfusion of 2×10^9 PD-1 edited TILs per kg body weight - Colorectal Cancer (CRC), Tumor Infiltrating Lymphocytes | Phase 1 | Recruiting | Ruijin Hospital | 29 | 2024-12-31 | 2025-06-24 |
| A Study of GC101 TIL in Advanced Melanoma (BZ) GC101 TIL - Tumor Infiltrating Lymphocytes, Safety | Phase 1 / Phase 2 | Completed | Shanghai Juncell Therapeutics | 18 | 2023-11-08 | 2025-12-23 |
| A Phase I Study of GC101 TIL in Advanced Solid Tumors TIL therapy - Tumor Infiltrating Lymphocytes, Safety | Phase 1 | Completed | Shanghai Juncell Therapeutics | 43 | 2022-10-12 | 2025-12-10 |
| Efficacy and Safety of TILs in Treatment of Patients With Advanced or Metastatic Refractory Gynecological Cancer Autologous tumor-infiltrating lymphocytes - Tumor Infiltrating Lymphocytes | Phase 1 / Phase 2 | Not yet recruiting | Women's Hospital School Of Medicine Zhejiang University | 91 | 2022-01-01 | 2021-12-10 |
Drug-Related Side Effects and Adverse Reactions (2) · Colorectal Neoplasms (1) · Melanoma (1)
Chemically-Induced Disorders (2) · Neoplasms (2) · Neoplasms by Site (2) · Colonic Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Gastrointestinal Diseases (1) · Gastrointestinal Neoplasms (1) · Intestinal Diseases (1) · Intestinal Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms, Germ Cell and Embryonal (1) · Neoplasms, Nerve Tissue (1) · Neuroectodermal Tumors (1) · Neuroendocrine Tumors (1)
Shanghai Juncell Therapeutics (2) · Ruijin Hospital (1) · Women's Hospital School Of Medicine Zhejiang University (1)
China (3)
Hui Wang, MD (1) · Jun Guo (1)