15 recruiting, 3 completed, 1 not yet recruiting, 1 unknown. 11 Early Phase 1, 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 11 | Recruiting 10, Completed 1 |
| Phase 1 | 7 | Recruiting 3, Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 3 | Recruiting 2, Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of TIL in Advanced Solid Tumors (CZ) GC101TIL - Solid Tumor, Adult | Phase 1 | Not yet recruiting | Shanghai Juncell Therapeutics | 30 | 2026-12-08 | 2026-08-05 |
| A Phase II Study of GC101 in NSCLC Autologous Tumor Infiltrating Lymphocytes - Non Small Cell Lung Cancer | Phase 2 | Recruiting | Shanghai Juncell Therapeutics | 28 | 2026-06-01 | 2026-08-05 |
| A Study of GC203 TIL in Advanced Solid Tumors (NF) GC203 TIL - Solid Tumors, Adult | Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 8 | 2026-01-30 | 2026-08-05 |
| A Study of GC203 TIL in PDCA (RJ) GC203 TIL - Pancreatic Cancer, Pancratic Ductal Adenocarcinoma | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 10 | 2025-02-10 | 2026-08-05 |
| A Study of GC101 TIL in Advanced Melanoma GC101 TIL, dacarbazine, temozolomide, paclitaxel ,platinum or cisplatin - Melanoma | Phase 2 | Recruiting | Shanghai Juncell Therapeutics | 98 | 2024-12-20 | 2026-08-05 |
| A Phase Ib Study of GC101 in NSCLC Autologous Tumor Infiltrating Lymphocytes - Non Small Cell Lung Cancer Metastatic, Non Small Cell Lung Cancer | Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 20 | 2024-10-14 | 2026-08-05 |
| A Study of GC203 TIL in Advanced Malignant Solid Tumors Engineering Tumor Infiltrating Lymphocytes - Solid Tumor, Gynecologic Cancer | Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 18 | 2024-05-29 | 2025-12-11 |
| A Study of GC101 TIL in Advanced Melanoma (BZ) GC101 TIL - Tumor Infiltrating Lymphocytes, Safety | Phase 1 / Phase 2 | Completed | Shanghai Juncell Therapeutics | 18 | 2023-11-08 | 2025-12-23 |
| A Study of TIL in Advanced Solid Tumors (DFGD) GC203 TIL(gene-edited TIL) or autologous TILs - Advanced Solid Tumor, Tumor Infiltrating Lymphocytes | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 30 | 2023-04-01 | 2025-12-16 |
| A Phase I Study of GC101 TIL in Advanced Solid Tumors TIL therapy - Tumor Infiltrating Lymphocytes, Safety | Phase 1 | Completed | Shanghai Juncell Therapeutics | 43 | 2022-10-12 | 2025-12-10 |
| A Study of GC203 TIL in Advanced Gynecologic Tumors (10hospital) Membrane Bound Cytokine Modified TIL - Advanced Gynecologic Tumors, TIL Engineered With Membrane-Binding Cytokine | Early Phase 1 | Completed | Shanghai Juncell Therapeutics | 26 | 2022-03-10 | 2025-12-11 |
| A Clinical Study on TIL for the Treatment of Advanced Solid Tumors Tumor Infiltrating Lymphocytes - Advanced Solid Tumor, Tumor Infiltrating Lymphocytes | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-12-10 | 2026-08-05 |
| A Study of GC101 TIL in Advanced Breast Cancer (10hospital) Tumor Infiltrating Lymphocytes (TIL) - Breast Cancer, Treatment Side Effects | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-11-19 | 2025-12-11 |
| A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital) Signal Switch Receptor Modified TIL - Advanced Gynecologic Tumors, Signal Switch Receptor Modified TIL | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-09-26 | 2025-12-11 |
| A Study of GC101 TIL in Advanced Melanoma (10hospital) Tumor Infiltrating Lymphocyte - Advanced Melanoma, Tumor Infiltrating Lymphocyte | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-09-26 | 2025-12-11 |
| A Study of GC101 TIL in Advanced Hepatobiliary-Pancreatic Cancers (10hospital) Tumor Infiltrating Lymphocyte - Advanced Liver Cancers, Tumor Infiltrating Lymphocyte | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-09-26 | 2025-12-11 |
| A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital) Tumor Infiltrating Lymphocytes (TIL) - Gastrointestinal Tumor | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-06-30 | 2026-08-05 |
| Study of GC101 TIL in Brain Glioma (Soochow2) Tumor Infiltrating Lymphocytes (TIL) - Glioma | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 50 | 2021-05-06 | 2026-08-05 |
| A Study of GC101 TIL in Advanced Solid Tumors (TR) Tumor Infiltrating Lymphocytes (TIL) - Advanced Solid Tumors | Early Phase 1 | Recruiting | Shanghai Juncell Therapeutics | 20 | 2021-04-22 | 2026-08-05 |
| Study on TIL for the Treatment of r/r Gynecologic Tumors Tumor Infiltrating Lymphocytes (TIL) - Gynecologic Cancer | Phase 1 | Unknown | Shanghai 10th People's Hospital | 15 | 2021-01-04 | 2024-03-06 |
Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Drug-Related Side Effects and Adverse Reactions (2) · Melanoma (2) · Digestive System Neoplasms (1) · Gastrointestinal Neoplasms (1) · Glioma (1) · Lung Neoplasms (1) · Pancreatic Neoplasms (1)
Cisplatin (1) · Dacarbazine (1) · Temozolomide (1)
China (20)
Huangming Hong (1) · Jun Guo (1) · LiJun Ma (1) · Qian Zhang (1) · Qing Lan (1) · Qing Xu (1) · Wenlong Yu (1)