13 completed. 13 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 13 |
| Phase 2 | 7 | Completed 7 |
Follow Tinnitus: new trials by email Literature Review of Tinnitus trials Research Report on Tinnitus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acute Nicotine Gum and Tinnitus Loudness in Non-Smoking Adults Nicotine polacrilex gum 4 mg, Placebo gum - Tinnitus, Chronic Subjective Tinnitus | Phase 1 / Phase 2 | Completed | San Diego State University | 29 | 2026-03-25 | 2026-10-16 |
| Blinding and Adverse Effects of Ultrasonic Vagus Nerve Stimulation (U-VNS) Ultrasound Vagus Nerve Stimulation (U-VNS), Sham U-VNS - U-VNS, Sham U-VNS | Phase 1 / Phase 2 | Completed | University of Nottingham | 20 | 2024-12-10 | 2025-07-29 |
| Treatment of Tinnitus With Olanzapine Olanzapine 5 Mg ORAL TABLET, Placebo Drug - Tinnitus, Tinnitus, Subjective | Phase 1 | Completed | University of Sao Paulo | 50 | 2023-10-01 | 2026-09-15 |
| OTO-313 in Subjects With Subjective Tinnitus OTO-313, Placebo - Tinnitus, Subjective | Phase 1 / Phase 2 | Completed | Otonomy, Inc. | 43 | 2019-04-04 | 2022-12-23 |
| Study to Evaluate SPI-1005 in Adults With Meniere's Disease SPI-1005 - Meniere's Disease | Phase 1 / Phase 2 | Completed | Sound Pharmaceuticals, Incorporated | 40 | 2015-12-01 | 2026-06-29 |
| Evaluation of Adding Lidocaine to Dexamethasone in Intra-tympanic Injection for Management of Tinnitus Intra-tympanic injection of drugs, Data management of intratympanic drugs - Tinnitus | Phase 1 | Completed | saad elzayat | 44 | 2015-03-01 | 2017-08-29 |
| Pilot Study of Deep Brain Stimulation (DBS) in Area LC for Chronic Tinnitus Deep Brain Stimulation (DBS) - Tinnitus | Phase 1 | Completed | Paul Larson | 10 | 2014-01-01 | 2019-04-18 |
| Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus reactive auditory training, Interactive auditory training - Tinnitus | Phase 1 / Phase 2 | Completed | Nottingham University Hospitals NHS Trust | 60 | 2011-08-01 | 2016-11-04 |
| Transcranial Magnetic Stimulation for Tinnitus repetitive transcranial magnetic stimulation (rTMS), placebo rTMS - Tinnitus | Phase 1 / Phase 2 | Completed | VA Office of Research and Development | 70 | 2011-03-01 | 2017-03-29 |
| OTO-104 for Meniere's Disease OTO-104 (steroid) 3 mg, Placebo, OTO-104 (steroid) 12 mg - Meniere's Disease | Phase 1 | Completed | Otonomy, Inc. | 44 | 2010-03-01 | 2011-06-08 |
| Cognitive Behavioral Therapy (CBT) for Tinnitus Cognitive Behavioral Therapy, Tinnitus Education - Tinnitus | Phase 1 / Phase 2 | Completed | US Department of Veterans Affairs | 33 | 2009-02-01 | 2015-05-06 |
| Clinical Trial of Acamprosate for Tinnitus Acamprosate, Placebo - Tinnitus | Phase 1 | Completed | Oregon Health and Science University | 154 | 2008-01-01 | 2016-11-08 |
| The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus Tinnitus retraining therapy, Sound therapy - Tinnitus | Phase 1 | Completed | Tinnitus Research Consortium | 41 | 2005-11-01 | 2009-09-24 |
Hearing Loss (2) · Meniere Disease (2) · Vertigo (2)
Ear Diseases (13) · Hearing Disorders (13) · Nervous System Diseases (13) · Neurologic Manifestations (13) · Otorhinolaryngologic Diseases (13) · Pathological Conditions, Signs and Symptoms (13) · Sensation Disorders (13) · Signs and Symptoms (13) · Endolymphatic Hydrops (2) · Labyrinth Diseases (2) · Vestibular Diseases (2)
Acamprosate (1) · Cognitive Behavioral Therapy (1) · Deep Brain Stimulation (1) · Lidocaine (1) · Nicotine Chewing Gum (1) · Olanzapine (1) · Steroids (1) · Tablets (1) · Transcranial Magnetic Stimulation (1) · ebselen (1)
Otonomy, Inc. (2) · Nottingham University Hospitals NHS Trust (1) · Oregon Health and Science University (1) · Paul Larson (1) · San Diego State University (1) · Sound Pharmaceuticals, Incorporated (1) · Tinnitus Research Consortium (1) · US Department of Veterans Affairs (1) · University of Nottingham (1) · University of Sao Paulo (1) · VA Office of Research and Development (1) · saad elzayat (1)
United States (9) · United Kingdom (2) · Brazil (1)
Carl LeBel, PhD (1) · Carol A Bauer, MD (1) · Deborah Hall, Professor (1) · Jonathan Kil, MD (1) · Paul Larson, MD (1) · Robert D. Kerns, PhD (1) · Robert Folmer, PhD (1) · Steven Cheung, MD (1) · William H Martin, Ph.D. (1) · Xianhui Wang (1) · Yongbing Shi, M.D., Ph.D. (1)
PMID 15474106, PMID 25215617, PMID 25470623, PMID 26181507, PMID 28183355, PMID 30738400, PMID 31553940, PMID 32483557