234 unknown. 234 Phase 1, 113 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 234 | Unknown 234 |
| Phase 2 | 113 | Unknown 113 |
Follow Thoracic Neoplasms: new trials by email Literature Review of Thoracic Neoplasms trials Research Report on Thoracic Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer SHR-A2102, Adebelimab (SHR-1316), SHR-8068 - Non-Small Cell Lung Cancer | Phase 1 / Phase 2 | Unknown | Shanghai Hengrui Pharmaceutical Co., Ltd. | 124 | 2024-09-27 | 2024-11-12 |
| PH009-1 in Patients With EGFR Mutation Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) PH009-1 tablet - Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | Phase 1 / Phase 2 | Unknown | Suzhou Puhe Pharmaceutical Technology Co., LTD | 96 | 2024-09-10 | 2024-09-19 |
| Radiotherapy to All Residual Lesions After Chemoimmunotherapy Radiotherapy to all residual lesions, Chemoimmunotherapy - Extensive-stage Small Cell Lung Cancer | Phase 1 / Phase 2 | Unknown | Anhui Provincial Hospital | 150 | 2024-06-01 | 2024-08-09 |
| Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC Cancer nutritional treatment regimen (Spirulina Bifidobacterium Capsules, Fish Oil Grape Seed Blueberry Soft Capsules, Ganoderma Spore Oil Soft Capsules) - Long-Term Effects Secondary to Cancer Therapy | Phase 1 | Unknown | The First Affiliated Hospital of Dalian Medical University | 120 | 2024-04-15 | 2024-04-10 |
| Study of WM-A1-3389 in Participants With Advanced or Metastatic Solid Tumors and Non-Small Cell Lung Cancer (MK-3475-E90/KEYNOTE-E90) WM-A1-3389, Pembrolizumab - Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 | Unknown | Wellmarker Bio | 54 | 2024-03-14 | 2024-03-12 |
| Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors UCMYM802 Injection - Malignant Mesothelioma, Colorectal Cancer | Phase 1 | Unknown | UTC Therapeutics Inc. | 24 | 2024-03-05 | 2024-07-24 |
| The Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Centipeda Minima (CM) in Lung Cancer Centipeda minima+PD-1/PD-L1 inhibitor, PD-1/PD-L1 inhibitor - Lung Cancer | Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 8 | 2024-02-07 | 2024-04-17 |
| Trial of Tumor Vaccine Used for Adjuvant Therapy in Post Radical Operation Patients With Lung Cancer Tumor Vaccine - Lung Cancer | Phase 1 / Phase 2 | Unknown | Yongchang Zhang | 30 | 2024-01-16 | 2023-12-29 |
| TIL Therapy for Patients With Advanced Solid Tumors Tumor-infiltrating lymphocytes, IL-2 - Advanced Breast Cancer, Advanced Lung Cancer | Phase 1 | Unknown | NeogenTC | 12 | 2024-01-01 | 2023-10-30 |
| Thoracic Consolidation Radiotherapy for ES-SCLC Treated With Chemo-immunotherapy thoracic radiotherapy - Small Cell Lung Cancer Extensive Stage | Phase 1 | Unknown | Fudan University | 28 | 2023-12-01 | 2024-01-09 |
| Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin Administration Cisplatine Teva® - Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung | Phase 1 | Unknown | Dr Jean Yannis PERENTES | 39 | 2023-11-24 | 2024-02-28 |
| Combining ICI With SBRT or HypoFrx-RT for ES NSCLC Stereotactic body radiotherapy, Hypofractionated radiotherapy, Durvalumab - Non-small Cell Lung Cancer, Non-small Cell Carcinoma | Phase 1 / Phase 2 | Unknown | Alexander Chi | 83 | 2023-10-09 | 2023-10-03 |
| Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors CEA CAR-T cells - Gastric Cancer, Colon Cancer | Phase 1 | Unknown | Chongqing Precision Biotech Co., Ltd | 36 | 2023-09-30 | 2023-11-08 |
| OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion. PITAC - Malignant Pleural Effusion, Pleural Neoplasms | Phase 1 | Unknown | Odense University Hospital | 20 | 2023-09-15 | 2024-05-20 |
| CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors CEA-targeted CAR-T cells - Gastric Cancer, Colon Cancer | Phase 1 / Phase 2 | Unknown | Chongqing Precision Biotech Co., Ltd | 60 | 2023-09-07 | 2024-08-09 |
| Study of Selinexor Combined With Olaparib in Relapsed/Refractory Extensive Stage Small Cell Lung Cancer Selinexor，Olaparib - Extensive-stage Small Cell Lung Cancer | Phase 1 / Phase 2 | Unknown | Tianjin Medical University Cancer Institute and Hospital | 49 | 2023-09-01 | 2023-08-04 |
| Tirellizumab Combined With Chemotherapy Monotherapy for Non-small Cell Lung Cancer Tirelizumab；Chemotherapy monotherapy - Non-small Cell Lung Cancer | Phase 1 | Unknown | Second Affiliated Hospital of Guangzhou Medical University | 31 | 2023-08-01 | 2023-07-28 |
| A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies ILB-2109, Toripalimab - Head and Neck Cancer, Cervical Cancer | Phase 1 / Phase 2 | Unknown | Innolake Biopharm | 200 | 2023-07-25 | 2024-05-21 |
| CTS2190 Phase I /II Clinical Study in Patients CTS2190 capsules - Solid Tumors, Pancreatic Cancer | Phase 1 / Phase 2 | Unknown | CytosinLab Therapeutics Co., Ltd. | 224 | 2023-06-26 | 2024-08-23 |
| A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors RC198 Injection - Melanoma, Urothelial Carcinoma | Phase 1 | Unknown | RemeGen Co., Ltd. | 48 | 2023-06-05 | 2024-08-16 |
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Carcinoma, Non-Small-Cell Lung (155) · Lung Neoplasms (59) · Small Cell Lung Carcinoma (28) · Colorectal Neoplasms (25) · Melanoma (25) · Pancreatic Neoplasms (23) · Breast Neoplasms (22) · Ovarian Neoplasms (19) · Stomach Neoplasms (17) · Carcinoma, Renal Cell (15) · Head and Neck Neoplasms (15) · Neoplasms (14) · Carcinoma, Hepatocellular (11) · Esophageal Neoplasms (11) · Endometrial Neoplasms (10)
Neoplasms by Site (233) · Respiratory Tract Neoplasms (233) · Respiratory Tract Diseases (229) · Lung Diseases (222) · Neoplasms (220) · Bronchial Neoplasms (178) · Carcinoma, Bronchogenic (177) · Lung Neoplasms (168) · Neoplasms by Histologic Type (63) · Neoplasms, Glandular and Epithelial (50) · Skin and Connective Tissue Diseases (49) · Skin Diseases (48) · Digestive System Diseases (47) · Digestive System Neoplasms (47)
pembrolizumab (15) · Cisplatin (11) · Docetaxel (8) · Nivolumab (7) · Radiotherapy (7) · Gefitinib (6) · apatinib (6) · Pemetrexed (5) · anlotinib (5) · camrelizumab (5) · durvalumab (5) · osimertinib (5) · toripalimab (5) · Afatinib (4) · Carboplatin (4)
Sun Yat-sen University (8) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (5) · Betta Pharmaceuticals Co., Ltd. (4) · Tianjin Medical University Cancer Institute and Hospital (4) · Fudan University (3) · Jiangsu Hansoh Pharmaceutical Co., Ltd. (3) · PersonGen BioTherapeutics (Suzhou) Co., Ltd. (3) · AHS Cancer Control Alberta (2) · Affiliated Hospital of Jiangnan University (2) · Assiut University (2) · BGI, China (2) · Biocad (2) · CSPC ZhongQi Pharmaceutical Technology Co., Ltd. (2) · Chongqing Precision Biotech Co., Ltd (2) · First Affiliated Hospital of Zhejiang University (2)
China (123) · United States (45) · South Korea (10) · Australia (9) · Canada (5) · France (5) · Israel (5) · United Kingdom (5) · Spain (4) · Taiwan (4) · Japan (3) · Belgium (2) · Italy (2) · Poland (2) · Russia (2)
Yuankai Shi, MD (3) · Jack D. Burton, MD (2) · Lin Yang, Ph.D. (2) · Shun Lu, Doctor (2) · Yinghui Sun, PhD (2) · A.J. de Langen, MD, PhD (1) · Albert Yu, MD (1) · Alexander Chi, MD (1) · Anish Thomas, MD (1) · Anna Farago, MD, PhD (1) · Baohui Han (1) · Baohui Han, Doctor (1)
PMID 14679114, PMID 14967075, PMID 15457249, PMID 15886314, PMID 16818618, PMID 16818691, PMID 18077538, PMID 19122144, PMID 20087963, PMID 20459769, PMID 20923544, PMID 21565397, PMID 21931708, PMID 22325357, PMID 22452895, PMID 22452896, PMID 22461641, PMID 22761469, PMID 23610105, PMID 23816960, PMID 23816963, PMID 24351336, PMID 24439929, PMID 24668644, PMID 25552401, PMID 25747273, PMID 25899785, PMID 26156651, PMID 26228759, PMID 26773716, PMID 26871284, PMID 27577069, PMID 28054442, PMID 29692997, PMID 30032814, PMID 30381078, PMID 30596880, PMID 30951733, PMID 31027916, PMID 31105267, PMID 31191007, PMID 31400383, PMID 32224416, PMID 32489249, PMID 32614698, PMID 32916310, PMID 32918045, PMID 33493586, PMID 33524601, PMID 34965951
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