8 completed, 4 unknown, 1 recruiting. 3 Phase 2, 3 Phase 3, 2 Not applicable, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Streptococcus Pneumoniae Infection: new trials by email Literature Review of Streptococcus Pneumoniae Infection trials Research Report on Streptococcus Pneumoniae Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial of the 24-valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid) 24-valent pneumococcal polysaccharide conjugate vaccine (CRM197/tetanus toxoid) (referred to as PCV24) (dose M), PCV24 vaccine (dose H), PCV24 vaccine (dose M) - Streptococcus Pneumoniae Infection | Phase 1 / Phase 2 | Recruiting | CanSino Biologics Inc. | 854 | 2026-05-24 | 2026-08-05 |
| Curian S. Pneumo/Legionella Assay Beta Clinical Trial Protocol N/A- There is no intervention. - Streptococcus Pneumoniae Infection, Legionella Pneumophila Serogroup 1 Infection | Completed | Meridian Bioscience, Inc. | 199 | 2023-02-01 | 2025-01-29 | |
| Phase III Clinical Trial of 13-valent Pneumococcal Conjugate Vaccine (Multivalent Conjugate) in Infants 13-valent pneumococcal conjugate vaccine (multivalent conjugate), Prevenar 13 - Streptococcus Pneumoniae Infection | Phase 3 | Unknown | Fosun Adgenvax Biopharmaceutical Co.,Ltd. | 1800 | 2022-11-04 | 2024-10-01 |
| Prevention of Pneumococcal Infections: Impact Collaborative Medico-pharmaceutical Care Structured to Improve Vaccination Coverage of Patients at Risk. Structured medico-pharmaceutical collaboration - Streptococcus Pneumoniae Infection | Not applicable | Completed | Centre Hospitalier Universitaire de Nīmes | 646 | 2022-09-19 | 2025-12-04 |
| A Controlled Human Pneumococcal Infection Model (PIM) Study Sp_6B, Amoxicillin 500 mg - Streptococcus Pneumoniae Infection | Not applicable | Completed | Radboud University Medical Center | 20 | 2022-05-31 | 2023-02-22 |
| Epidemiology and Household Transmission of Streptococcus Pneumoniae and Respiratory Syncytial Virus Streptococcus Pneumoniae Infection, Respiratory Syncytial Virus Infections | Unknown | Mackay Memorial Hospital | 240 | 2021-10-01 | 2021-08-24 | |
| Pneumococcal Nasopharyngeal Colonization as Predictor of Community-Acquired Pneumonia (CAP) in Adults With Chronic Diseases. nasopharyngeal aspirate - Streptococcus Pneumoniae Pneumonia, Streptococcus Pneumoniae Infection | Unknown | Universidad de la Sabana | 810 | 2020-12-01 | 2021-06-30 | |
| The Effect of Fractional Doses of Pneumococcal Conjugate Vaccines on Immunogenicity and Carriage in Kenyan Infants PCV10, PCV13 - Pneumococcal Infection, Streptococcus Pneumoniae Infection | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 2100 | 2019-03-21 | 2024-11-12 |
| Determination of the Utility of Pfizer's Pneumococcal Urine Antigen Test in Children 5 Years of Age or Younger With Community Acquired Pneumonia in Guatemala Urinary antigen detection assay - Community-acquired Pneumonia, Streptococcus Pneumoniae Infection | Completed | University of Colorado, Denver | 959 | 2019-03-13 | 2022-05-04 | |
| CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study PCV13 - Invasive Pneumococcal Disease, Protection Against, Streptococcus Pneumoniae Infection | Phase 2 / Phase 3 | Completed | University of British Columbia | 248 | 2018-08-23 | 2024-03-04 |
| Understanding Pneumococcal Carriage and Disease 2017-2020 Nasopharyngeal swab, blood sampling - Streptococcus Pneumoniae Infection, Streptococcus Pneumoniae, Invasive Disease | Unknown | University of Oxford | 2400 | 2017-06-26 | 2020-10-20 | |
| Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004) Prevnar 13®, V114 1x:1x:1x, V114 2x:2x:2x - Streptococcus Pneumoniae Infection, Pneumococcal Infections | Phase 1 / Phase 2 | Completed | Merck Sharp & Dohme LLC | 341 | 2014-01-28 | 2019-06-24 |
| Effect of Two Versus Three Pneumococcal Conjugate Vaccinations PCV7 - Streptococcus Pneumoniae Infection | Phase 3 | Completed | UMC Utrecht | 1005 | 2005-06-01 | 2011-08-22 |
Pneumococcal Infections (13) · Pneumonia (3) · Community-Acquired Pneumonia (2) · Asymptomatic Infections (1) · Respiratory Syncytial Virus Infections (1) · Respiratory Tract Infections (1)
Bacterial Infections (13) · Bacterial Infections and Mycoses (13) · Gram-Positive Bacterial Infections (13) · Infections (13) · Streptococcal Infections (13) · Respiratory Tract Diseases (4) · Lung Diseases (3) · Respiratory Tract Infections (3) · Community-Acquired Infections (2) · Asymptomatic Diseases (1) · Disease Attributes (1) · Mononegavirales Infections (1) · Paramyxoviridae Infections (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
13-valent pneumococcal vaccine (5) · 10-valent pneumococcal conjugate vaccine (1) · Amoxicillin (1) · Blood Specimen Collection (1) · CRM197 (non-toxic variant of diphtheria toxin) (1) · Heptavalent Pneumococcal Conjugate Vaccine (1) · PHiD-CV vaccine (1) · Protons (1) · Referral and Consultation (1) · Tetanus Toxoid (1)
CanSino Biologics Inc. (1) · Centre Hospitalier Universitaire de Nīmes (1) · Fosun Adgenvax Biopharmaceutical Co.,Ltd. (1) · London School of Hygiene and Tropical Medicine (1) · Mackay Memorial Hospital (1) · Merck Sharp & Dohme LLC (1) · Meridian Bioscience, Inc. (1) · Radboud University Medical Center (1) · UMC Utrecht (1) · Universidad de la Sabana (1) · University of British Columbia (1) · University of Colorado, Denver (1) · University of Oxford (1)
China (2) · Canada (1) · Colombia (1) · France (1) · Guatemala (1) · Kenya (1) · Netherlands (1) · United Kingdom (1) · United States (1)
Claudia M Poveda, MD, Spc., Fellow (1) · Edwin Asturias, MD (1) · Elisabeth A. M. Sanders, MD, PhD (1) · Florent Dubois (1) · Hsin Chi, Doctor (1) · J. Anthony G Scott, DTMH FMedSci (1) · Manish Sadarangani, MD (1) · Zhiqiang Xie, Master (1)
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