40 completed, 5 terminated, 3 withdrawn. 23 Phase 1, 20 Phase 2, 6 Not applicable, 1 Early Phase 1, 1 Phase 3.
Follow Stage IV Ovarian Epithelial Cancer: new trials by email Literature Review of Stage IV Ovarian Epithelial Cancer trials Research Report on Stage IV Ovarian Epithelial Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer metformin hydrochloride, placebo, Chemotherapy - Brenner Tumor, Malignant Ascites | Phase 2 | Completed | University of Chicago | 111 | 2015-02-25 | 2026-03-27 |
| Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer palliative care, educational intervention, quality-of-life assessment - Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor | Not applicable | Withdrawn | City of Hope Medical Center | 2014-12-01 | 2014-12-23 | |
| Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery propranolol hydrochloride, Correlative Studies - Male Breast Cancer, Recurrent Melanoma | Early Phase 1 | Completed | William Carson | 1 | 2014-01-21 | 2022-12-06 |
| Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who Are in Remission ALVAC(2)-NY-ESO-1 (M)/TRICOM vaccine, IDO1 inhibitor INCB024360, laboratory biomarker analysis - Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer | Phase 1 / Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2013-12-01 | 2013-12-18 | |
| Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection vorinostat, diagnostic laboratory biomarker analysis, pharmacological study - HIV Infection, Recurrent Anal Cancer | Phase 1 | Terminated | AIDS Malignancy Consortium | 17 | 2013-11-01 | 2020-07-29 |
| Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers educational intervention, telephone-based intervention, quality-of-life assessment - Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter | Not applicable | Completed | City of Hope Medical Center | 200 | 2013-10-29 | 2026-10-01 |
| Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer ALVAC(2)-NY-ESO-1 (M)/TRICOM vaccine, sirolimus, laboratory biomarker analysis - Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer | Phase 1 | Completed | Roswell Park Cancer Institute | 7 | 2012-08-20 | 2020-03-27 |
| Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant management of therapy complications, musculoskeletal complications management/prevention - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Withdrawn | Roswell Park Cancer Institute | 2012-05-01 | 2012-07-09 | |
| Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer stereotactic body radiation therapy, positron emission tomography, computed tomography - Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor | Phase 1 | Terminated | Stanford University | 1 | 2012-04-01 | 2017-04-28 |
| Vaccine Therapy in Treating Patients With Stage III-IV or Recurrent Ovarian Cancer pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine, laboratory biomarker analysis - Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor | Phase 1 | Completed | University of Washington | 25 | 2012-03-06 | 2021-02-25 |
| Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors veliparib, capecitabine, oxaliplatin - Adenocarcinoma of the Pancreas, Adenocarcinoma of the Stomach | Phase 1 | Terminated | National Cancer Institute (NCI) | 16 | 2010-10-01 | 2014-04-02 |
| Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload deferasirox - Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Terminated | City of Hope Medical Center | 1 | 2010-07-01 | 2019-06-18 |
| Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors temsirolimus, vinorelbine ditartrate - Extensive Stage Small Cell Lung Cancer, Hereditary Paraganglioma | Phase 1 | Completed | University of Southern California | 19 | 2010-06-01 | 2016-06-13 |
| Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires - Advanced Malignant Mesothelioma, Carcinoma of the Appendix | Not applicable | Completed | Wake Forest University Health Sciences | 10 | 2010-05-01 | 2018-07-03 |
| Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies stereotactic radiosurgery, quality-of-life assessment - Fallopian Tube Cancer, Ovarian Sarcoma | Phase 2 | Completed | Case Comprehensive Cancer Center | 50 | 2009-05-01 | 2013-11-28 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancer gemcitabine hydrochloride, tanespimycin - Primary Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 29 | 2007-10-01 | 2014-05-20 |
| Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors paclitaxel, carboplatin, temsirolimus - Ovarian Sarcoma, Ovarian Stromal Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 38 | 2007-02-01 | 2014-06-19 |
| Sunitinib Malate in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer sunitinib malate, laboratory biomarker analysis - Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 31 | 2007-01-01 | 2015-01-27 |
| Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma ziv-aflibercept - Fallopian Tube Cancer, Female Reproductive Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 63 | 2006-09-01 | 2015-12-07 |
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Carcinoma, Ovarian Epithelial (48) · Breast Neoplasms (17) · Fallopian Tube Neoplasms (17) · Carcinoma, Non-Small-Cell Lung (8) · Colonic Neoplasms (8) · Uterine Cervical Neoplasms (8) · Pancreatic Neoplasms (7) · Stomach Neoplasms (7) · Breast Neoplasms, Male (6) · Brenner Tumor (6) · Endometrial Neoplasms (6) · Rectal Neoplasms (6) · Squamous Cell Carcinoma of Head and Neck (6) · Testicular Neoplasms (6) · Burkitt Lymphoma (5)
Adnexal Diseases (48) · Carcinoma (48) · Endocrine Gland Neoplasms (48) · Endocrine System Diseases (48) · Female Urogenital Diseases (48) · Female Urogenital Diseases and Pregnancy Complications (48) · Genital Diseases (48) · Genital Diseases, Female (48) · Genital Neoplasms, Female (48) · Gonadal Disorders (48) · Neoplasms by Histologic Type (48) · Neoplasms by Site (48) · Neoplasms, Glandular and Epithelial (48) · Ovarian Diseases (48) · Urogenital Diseases (48)
Taxes (7) · Paclitaxel (6) · Carboplatin (5) · Cisplatin (5) · Bevacizumab (4) · Erlotinib Hydrochloride (4) · Flow Cytometry (3) · Granulocyte-Macrophage Colony-Stimulating Factor (3) · Sirolimus (3) · sargramostim (3) · 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (2) · Early Intervention, Educational (2) · Immunoenzyme Techniques (2) · Immunologic Techniques (2) · Methods (2)
National Cancer Institute (NCI) (28) · University of Washington (5) · City of Hope Medical Center (3) · Roswell Park Cancer Institute (3) · Fred Hutchinson Cancer Center (2) · AIDS Malignancy Consortium (1) · Case Comprehensive Cancer Center (1) · Stanford University (1) · University of Chicago (1) · University of Southern California (1) · Wake Forest University Health Sciences (1) · William Carson (1)
United States (44) · Canada (3) · Japan (1)
Agustin Garcia (2) · Amit Oza (2) · Kunle Odunsi (2) · Mary Disis (2) · Antonius Miller (1) · Barbara Goff (1) · Betty Ferrell (1) · Charles Kunos (1) · Charles Rudin (1) · Christina Chu (1) · David Alberts (1) · David Solit (1) · Deborah Armstrong (1) · Elizabeth Kidd (1) · Ellen Chuang (1)
PMID 18974373, PMID 20357034, PMID 20837357, PMID 22541066, PMID 22664059, PMID 28817727, PMID 35429391, PMID 36326756, PMID 39362046, PMID 40132910
U10CA027469 (6), P30CA015083 (3), N01CM17101 (2), N01CM62201 (2), N01CM62203 (2), N01CM62204 (2), N01CM62205 (2), N01CM62209 (2), P01CA087971 (1), P30CA013330 (1), P30CA014520 (1), P30CA014599 (1), P30CA015704 (1), P30CA016056 (1), P30CA033572 (1)