5 recruiting, 1 completed. 3 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 3 |
| Not applicable | 1 | Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Stage III Nasopharyngeal Carcinoma AJCC v8: new trials by email Literature Review of Stage III Nasopharyngeal Carcinoma AJCC v8 trials Research Report on Stage III Nasopharyngeal Carcinoma AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection - Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 44 | 2026-05-27 | 2026-10-16 |
| Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer Best Practice, Biospecimen Collection, Cisplatin - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Recruiting | NRG Oncology | 98 | 2025-06-23 | 2026-08-17 |
| Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma Intensity-Modulated Radiation Therapy (IMRT), Radiographic Imaging, Biospecimen Collection - Nasopharyngeal Carcinoma, Stage III Nasopharyngeal Carcinoma AJCC v8 | Not applicable | Recruiting | University of California, San Francisco | 66 | 2025-03-18 | 2026-06-17 |
| A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC) Biopsy Procedure, Biospecimen Collection, Chest Radiography - Stage II Nasopharyngeal Carcinoma AJCC v8, Stage III Nasopharyngeal Carcinoma AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 50 | 2024-06-25 | 2026-10-14 |
| Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer Proton Beam Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration - Locally Advanced Head and Neck Squamous Cell Carcinoma, Locally Advanced Hypopharyngeal Squamous Cell Carcinoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 3 | 2020-10-19 | 2024-10-29 |
| Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer Biospecimen Collection, Questionnaire Administration - Carcinoma of Unknown Primary, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Recruiting | M.D. Anderson Cancer Center | 471 | 2016-12-29 | 2026-10-06 |
Nasopharyngeal Carcinoma (6) · Carcinoma (4) · Laryngeal Neoplasms (4) · Hypopharyngeal Neoplasms (3) · Mouth Neoplasms (2) · Oropharyngeal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Epstein-Barr Virus Infections (1) · Nasopharyngeal Neoplasms (1) · Neoplasms, Unknown Primary (1) · Stomatitis (1)
Head and Neck Neoplasms (6) · Nasopharyngeal Diseases (6) · Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms by Site (6) · Neoplasms, Glandular and Epithelial (6) · Otorhinolaryngologic Diseases (6) · Otorhinolaryngologic Neoplasms (6) · Pharyngeal Diseases (6) · Pharyngeal Neoplasms (6) · Stomatognathic Diseases (6) · Nasopharyngeal Neoplasms (5) · Laryngeal Diseases (4) · Respiratory Tract Diseases (4) · Respiratory Tract Neoplasms (4)
Magnetic Resonance Spectroscopy (4) · Specimen Handling (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Biopsy (2) · Cisplatin (2) · Phantoms, Imaging (2) · Platinum (2) · Radiotherapy, Intensity-Modulated (2) · Blood Specimen Collection (1) · Gemcitabine (1) · Mn(III) meso-tetrakis(N-n-butoxyethylpyridinium-2-yl)porphyrin (1) · Nivolumab (1) · Practice Guidelines as Topic (1) · Proton Therapy (1) · Protons (1)
M.D. Anderson Cancer Center (2) · National Cancer Institute (NCI) (2) · NRG Oncology (1) · University of California, San Francisco (1)
United States (6) · Australia (1) · Canada (1) · New Zealand (1) · Puerto Rico (1)
Clifton D Fuller (1) · David M Brizel (1) · Eileen H Shinn (1) · Matin Imanguli (1) · Robyn D Gartrell (1) · Sue Yom, MD, PhD (1)
R21DE019954 (1), U10CA180886 (1), UG1CA189867 (1), UM1CA186691 (1)