34 completed, 10 terminated, 8 active not recruiting, 2 withdrawn. 25 Not applicable, 16 Phase 2, 6 Phase 1, 4 Phase 3, 2 Early Phase 1.
Follow Stage IIA Breast Cancer: new trials by email Literature Review of Stage IIA Breast Cancer trials Research Report on Stage IIA Breast Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer Anastrozole, Therapeutic Conventional Surgery, Trastuzumab Deruxtecan - Early-stage Breast Cancer, Hormone Receptor Positive Breast Carcinoma | Phase 2 | Recruiting | Jonsson Comprehensive Cancer Center | 88 | 2020-10-09 | 2025-11-10 |
| Exercise Intervention in Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis - Cancer Survivor, Central Obesity | Not applicable | Withdrawn | University of Southern California | 2019-07-29 | 2019-10-24 | |
| Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer Radiation Therapy, Questionnaire Administration, Quality-of-Life Assessment - Ductal Breast Carcinoma, Invasive Breast Carcinoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 898 | 2018-03-12 | 2026-02-24 |
| Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer Hypofractionated Radiation Therapy - Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma | Phase 2 | Completed | University of Utah | 102 | 2017-12-12 | 2025-12-30 |
| Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction Electron Beam Therapy, Lumpectomy, Quality-of-Life Assessment - Stage IA Breast Cancer, Stage IB Breast Cancer | Phase 2 | Active not recruiting | Ohio State University Comprehensive Cancer Center | 108 | 2017-10-16 | 2026-06-03 |
| Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer Best Practice, Exercise Intervention, Quality-of-Life Assessment - Stage II Breast Cancer, Stage IIA Breast Cancer | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 4 | 2017-08-30 | 2023-12-14 |
| Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors Exercise Intervention, Laboratory Biomarker Analysis, Polar heart rate monitor - Cancer Survivor, No Evidence of Disease | Not applicable | Terminated | University of Southern California | 23 | 2017-08-17 | 2025-09-29 |
| Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancer Biopsy of Breast, Copanlisib, Laboratory Biomarker Analysis - Estrogen Receptor Positive, HER2/Neu Negative | Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 10 | 2017-08-02 | 2022-09-26 |
| Ultrasound in Detecting Taxane-Induced Neuropathy in Patients With Breast Cancer Biopsy, Questionnaire Administration, Ultrasound Tomography - Peripheral Neuropathy, Stage 0 Breast Cancer | Not applicable | Completed | Wake Forest University Health Sciences | 20 | 2017-05-11 | 2024-04-08 |
| Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery Biopsy of Breast - Invasive Breast Carcinoma, Stage II Breast Cancer | Phase 2 | Completed | NRG Oncology | 105 | 2017-04-13 | 2025-05-22 |
| Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness) Educational Intervention, Laboratory Biomarker Analysis, Meditation Therapy - Cancer Survivor, Early-Stage Breast Carcinoma | Not applicable | Unknown | Jonsson Comprehensive Cancer Center | 96 | 2017-02-20 | 2022-07-21 |
| Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgery Fulvestrant, Laboratory Biomarker Analysis, Palbociclib - Estrogen Receptor and/or Progesterone Receptor Positive, HER2/Neu Negative | Phase 2 | Completed | Ohio State University Comprehensive Cancer Center | 14 | 2017-02-16 | 2025-12-19 |
| Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca Doxorubicin, Cyclophosphamide, Paclitaxel - Breast Adenocarcinoma, Estrogen Receptor- Negative Breast Cancer | Phase 2 | Active not recruiting | Virginia Commonwealth University | 46 | 2017-01-24 | 2026-07-01 |
| S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER) Preventive Intervention, Quality-of-Life Assessment, Questionnaire Administration - Febrile Neutropenia, Stage 0 Breast Cancer | Not applicable | Completed | SWOG Cancer Research Network | 3665 | 2016-10-07 | 2022-10-20 |
| Vaccine Therapy in Preventing Cancer Recurrence in Patients With Non-Metastatic, Node Positive, HER2 Negative Breast Cancer That is in Remission Laboratory Biomarker Analysis, pUMVC3-IGFBP2-HER2-IGF1R Plasmid DNA Vaccine, Sargramostim - HER2/Neu Negative, No Evidence of Disease | Phase 1 | Completed | University of Washington | 32 | 2016-09-02 | 2024-09-19 |
| MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment Cardiopulmonary Exercise Testing, Magnetic Resonance Imaging - Healthy Subject, Stage IA Breast Cancer | Completed | Wake Forest University Health Sciences | 33 | 2016-08-25 | 2019-04-26 | |
| Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer Biospecimen Collection, Functional Magnetic Resonance Imaging, Questionnaire Administration - Healthy Subject, Stage 0 Breast Cancer | Completed | Stanford University | 178 | 2016-08-01 | 2022-07-27 | |
| Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin Educational Intervention, Internet-Based Intervention, Monitoring Device - Cancer Survivor, Healthy Subject | Not applicable | Completed | University of Wisconsin, Madison | 100 | 2016-07-01 | 2019-11-18 |
| Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors Computer-Assisted Cognitive Training, Questionnaire Administration, Standard Follow-Up Care - Cancer Survivor, Stage 0 Breast Cancer | Not applicable | Completed | Fred Hutchinson Cancer Center | 15 | 2016-05-01 | 2017-12-13 |
| Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer Dietary Intervention, Educational Intervention, Laboratory Biomarker Analysis - Obesity, Stage IA Breast Cancer | Not applicable | Completed | City of Hope Medical Center | 21 | 2016-03-22 | 2026-10-01 |
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Breast Neoplasms (56) · Breast Carcinoma In Situ (13) · Carcinoma, Intraductal, Noninfiltrating (8) · Triple Negative Breast Neoplasms (8) · Colorectal Neoplasms (4) · Carcinoma, Ductal, Breast (3) · Ovarian Neoplasms (3) · Prostatic Neoplasms (3) · Breast Neoplasms, Male (2) · Carcinoma, Lobular (2) · Depression (2) · Inflammatory Breast Neoplasms (2) · Obesity (2) · Astrocytoma (1) · Brain Neoplasms (1)
Breast Diseases (56) · Neoplasms (56) · Neoplasms by Site (56) · Skin Diseases (56) · Skin and Connective Tissue Diseases (56) · Carcinoma (20) · Neoplasms by Histologic Type (20) · Neoplasms, Glandular and Epithelial (20) · Carcinoma in Situ (17) · Adenocarcinoma (11) · Neoplasms, Ductal, Lobular, and Medullary (10) · Genital Diseases (5) · Urogenital Diseases (5) · Urogenital Neoplasms (5) · Breast Carcinoma In Situ (4)
Taxes (8) · Paclitaxel (7) · Carboplatin (6) · Cyclophosphamide (6) · Radiotherapy (5) · Doxorubicin (4) · Early Intervention, Educational (4) · Educational Status (4) · Methods (4) · Trastuzumab (4) · Albumin-Bound Paclitaxel (3) · Anastrozole (3) · Radiation (3) · Tamoxifen (3) · 130-nm albumin-bound paclitaxel (2)
Ohio State University Comprehensive Cancer Center (6) · City of Hope Medical Center (5) · National Cancer Institute (NCI) (5) · Rutgers, The State University of New Jersey (5) · University of Southern California (5) · Jonsson Comprehensive Cancer Center (3) · Wake Forest University Health Sciences (3) · NRG Oncology (2) · Roswell Park Cancer Institute (2) · University of Nebraska (2) · University of Washington (2) · Virginia Commonwealth University (2) · Albert Einstein College of Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Case Comprehensive Cancer Center (1)
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Joanne Mortimer (2) · Amulya C Yellala, MD (1) · Andrea Barsevick, PhD (1) · Anna Wu (1) · Antoinette Tan (1) · Arthur Blackstock (1) · Ayca Gucalp (1) · Bruce Haffty, MD (1) · Christina Dieli-Conwright (1) · Christina Dieli-Conwright, Ph.D. (1) · Christina Dieli-Conwright, PhD (1) · Cynthia Ma (1) · Cynthia Owusu (1) · David Spiegel (1) · Elizabeth C Reed (1)
PMID 24095609, PMID 24154719, PMID 24881463, PMID 25495490, PMID 26092816, PMID 27022111, PMID 27044936, PMID 28911092, PMID 29863451, PMID 29961039, PMID 30535101, PMID 30611839, PMID 30971205, PMID 31236810, PMID 31269914, PMID 31618131, PMID 32808383, PMID 33740205, PMID 34018031, PMID 34092112, PMID 34406839, PMID 35365139, PMID 35795051, PMID 36130057, PMID 36228177, PMID 36279134, PMID 36493334, PMID 36521078, PMID 36943254, PMID 37083300, PMID 37770704, PMID 37788414, PMID 38236702, PMID 38917400, PMID 39132946, PMID 40132910, PMID 40314623, PMID 40332918, PMID 40986647, PMID 41637791, PMID 42082270
P30CA014089 (5), P30CA012197 (3), P30CA072720 (3), P30CA013330 (2), P30CA015704 (2), P30CA016056 (2), P30CA016059 (2), P30CA036727 (2), U10CA180868 (2), 2004 (1), K07CA148888 (1), N01CM00071 (1), N01CM00099 (1), N01CM62204 (1), N01CN00033 (1)