8 completed, 2 terminated, 2 withdrawn, 1 active not recruiting. 7 Phase 2, 5 Phase 1, 2 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Terminated 2 |
| Phase 1 | 5 | Completed 2, Terminated 2, Withdrawn 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Stage I Adult Hodgkin Lymphoma: new trials by email Literature Review of Stage I Adult Hodgkin Lymphoma trials Research Report on Stage I Adult Hodgkin Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection C46/CCR5/P140K Lentiviral Vector-transduced Autologous HSPCs, Carmustine, Filgrastim - Human Immunodeficiency Virus 1 Positive, Stage I Adult Hodgkin Lymphoma | Phase 1 | Withdrawn | Fred Hutchinson Cancer Center | 2016-08-15 | 2018-11-20 | |
| Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas lenalidomide, etoposide, prednisone - Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | University of Chicago | 55 | 2014-07-29 | 2026-03-11 |
| Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant busulfan, etoposide, cyclophosphamide - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 33 | 2014-03-01 | 2015-08-13 |
| Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies vorinostat, tacrolimus, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | National Cancer Institute (NCI) | 12 | 2013-06-01 | 2018-07-24 |
| Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas brentuximab vedotin, rituximab, laboratory biomarker analysis - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Terminated | Northwestern University | 20 | 2013-03-05 | 2021-09-01 |
| Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant tetanus-CMV fusion peptide vaccine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | City of Hope Medical Center | 36 | 2012-10-29 | 2024-04-02 |
| Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant infection prophylaxis and management, laboratory biomarker analysis, flow cytometry - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Active not recruiting | City of Hope Medical Center | 153 | 2011-01-11 | 2026-10-22 | |
| Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies deferasirox, laboratory biomarker analysis, enzyme-linked immunosorbent assay - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Wake Forest University Health Sciences | 16 | 2011-01-01 | 2018-09-07 |
| Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin Lymphoma lopinavir, ritonavir, polymerase chain reaction - Hodgkin Lymphoma, Stage I Adult Hodgkin Lymphoma | Not applicable | Withdrawn | Mayo Clinic | 2010-11-01 | 2022-12-01 | |
| Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer beclomethasone dipropionate, placebo, tacrolimus - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 140 | 2007-04-01 | 2021-02-03 |
| Bortezomib, Ifosfamide, and Vinorelbine Tartrate in Treating Young Patients With Hodgkin's Lymphoma That is Recurrent or Did Not Respond to Previous Therapy ifosfamide, bortezomib, vinorelbine tartrate - Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Predominant Hodgkin Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 26 | 2007-01-01 | 2021-03-24 |
| Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma fenretinide, rituximab - Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 32 | 2005-10-01 | 2014-10-06 |
| Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Fred Hutchinson Cancer Center | 5 | 1999-11-01 | 2017-05-24 |
Hodgkin Disease (13) · Leukemia, Lymphocytic, Chronic, B-Cell (10) · Lymphoma, B-Cell, Marginal Zone (10) · Lymphoma, Follicular (10) · Lymphoma, Large B-Cell, Diffuse (10) · Lymphoma, Mantle-Cell (10) · Burkitt Lymphoma (9) · Lymphoma, Non-Hodgkin (9) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (9) · Waldenstrom Macroglobulinemia (9) · Lymphoma, Large-Cell, Immunoblastic (8) · Intraocular Lymphoma (7) · Lymphoma, T-Cell, Cutaneous (7) · Mycosis Fungoides (7) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (7)
Hemic and Lymphatic Diseases (13) · Immune System Diseases (13) · Immunoproliferative Disorders (13) · Lymphatic Diseases (13) · Lymphoproliferative Disorders (13) · Neoplasms (13) · Neoplasms by Histologic Type (13) · Lymphoma (12) · Disease Attributes (11) · Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Blood Protein Disorders (10) · Cardiovascular Diseases (10) · Chronic Disease (10) · Hematologic Diseases (10)
Rituximab (3) · Cyclophosphamide (2) · Cyclosporine (2) · Enzyme-Linked Immunosorbent Assay (2) · Etoposide (2) · Filgrastim (2) · Flow Cytometry (2) · Granulocyte Colony-Stimulating Factor (2) · Methotrexate (2) · Peripheral Blood Stem Cell Transplantation (2) · Polymerase Chain Reaction (2) · Tacrolimus (2) · merphos (2) · Antiviral Agents (1) · Beclomethasone (1)
Fred Hutchinson Cancer Center (3) · National Cancer Institute (NCI) (3) · City of Hope Medical Center (2) · Case Comprehensive Cancer Center (1) · Mayo Clinic (1) · Northwestern University (1) · University of Chicago (1) · Wake Forest University Health Sciences (1)
United States (13)
Ryotaro Nakamura (2) · Adam Petrich, MD (1) · Ajay Gopal (1) · Ann Woolfrey (1) · Brian Hill, MD (1) · Mary Ann Knovich, MD (1) · Mazyar Shadman (1) · Paul Martin (1) · Pavan Reddy (1) · Sonali Smith (1) · Stacey Rizza, M.D. (1) · Terzah Horton (1)
PMID 18698002, PMID 25833390, PMID 26853648, PMID 30562587, PMID 40720747
P30CA015704 (2), P01CA018029 (1), P30CA014599 (1), P30CA043703 (1), P30CA046592 (1), R01HL116217 (1), R21CA119519 (1), U10CA098543 (1)