80 recruiting, 78 completed, 48 unknown, 32 active not recruiting. 212 Phase 1, 90 Phase 2, 33 Not applicable, 3 Early Phase 1, 2 Phase 3.
Follow Solid Tumor, Adult: new trials by email Literature Review of Solid Tumor, Adult trials Research Report on Solid Tumor, Adult
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies Lactobacillus and Bifidobacterium, Placebo - Solid Tumor, Adult, Cytotoxicity | Not applicable | Not yet recruiting | Masonic Cancer Center, University of Minnesota | 40 | 2026-12-25 | 2026-02-03 |
| A Study of TIL in Advanced Solid Tumors (CZ) GC101TIL - Solid Tumor, Adult | Phase 1 | Not yet recruiting | Shanghai Juncell Therapeutics | 30 | 2026-12-08 | 2026-08-05 |
| Ivermectin Combined With Immune Checkpoint Inhibition in Cancer (ICONIC) Intermediate-dose ivermectin, High-dose ivermectin - Solid Tumor, Adult | Phase 2 | Not yet recruiting | University of Florida | 80 | 2026-12-01 | 2026-10-13 |
| HMPL-A830 in Solid Tumors HMPL-A830 - Solid Tumor, Adult | Phase 1 / Phase 2 | Recruiting | Hutchmed | 147 | 2026-09-24 | 2026-10-01 |
| UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations Blood Sample, Tissue Sample, Excess fluid Sample - Solid Tumor, Solid Tumor, Adult | Withdrawn | University of California, San Francisco | 2026-08-31 | 2026-09-02 | ||
| Imaging Study of [89Zr]DFO-YS5 for Cancer Detection [89Zr]DFO-YS5, Positron Emission Tomography (PET)-Computerized tomography (CT) - Bladder Cancer, Nerve Sheath Tumor | Phase 1 | Recruiting | Robert Flavell, MD, PhD | 40 | 2026-06-15 | 2026-10-01 |
| ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu Tremelimumab, Durvalumab - Solid Tumor, Adult, Malignant Solid Tumor | Early Phase 1 | Recruiting | University of California, Irvine | 34 | 2026-05-25 | 2026-07-07 |
| DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English - Solid Tumor, Solid Tumor, Adult | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 125 | 2026-01-23 | 2026-09-11 |
| Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM) Cohort A: Extensive Stage Small Cell Lung Cancer (ES-SCLC) Thoracic Tumor PULSAR (Personalized ultrahypofractionated stereotactic ablative radiotherapy), Cohort B: Brain metastasis PULSAR (Personalized ultrahypofractionated stereotactic ablative radiotherapy), Cohort C: Sarcoma Pre-Operative PULSAR - Small Cell Lung Cancer Extensive Stage, Brain Metastases | Phase 1 | Recruiting | University of Texas Southwestern Medical Center | 105 | 2025-10-28 | 2026-08-17 |
| A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors AXN-2510 - Solid Tumor, Adult | Phase 1 | Terminated | Axion Bio, Inc | 3 | 2025-09-15 | 2026-05-06 |
| Clinical Trial of the Safety and Efficacy of IBA Proton Therapy System PROTEUS® PLUS (Sichuan) Proton Beam Therapy (PBT) - Solid Tumor, Adult | Not applicable | Active not recruiting | Ion Beam Applications | 47 | 2025-08-19 | 2026-01-07 |
| Clinical Trial of the Safety and Efficacy of IBA Proton Therapy System PROTEUS® PLUS (Shenzhen) Proton Beam Therapy (PBT) - Solid Tumor, Adult | Not applicable | Active not recruiting | Ion Beam Applications | 47 | 2025-08-04 | 2026-01-16 |
| R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors R-5780 - Solid Tumor, Adult, Solid Tumor | Phase 1 | Recruiting | Rise Therapeutics LLC | 33 | 2025-08-01 | 2026-09-18 |
| A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors VS-7375, Cetuximab, Carboplatin + Pemetrexed + Pembrolizumab - Pancreatic Ductal Adenocarcinoma, Non Small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | Verastem, Inc. | 616 | 2025-06-24 | 2026-10-15 |
| A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression A2B395, xT CDx with HLA-LOH assay - Solid Tumor, Adult, Colorectal Cancer | Phase 1 / Phase 2 | Recruiting | A2 Biotherapeutics Inc. | 240 | 2025-05-22 | 2025-09-09 |
| Clinical Trial of the Safety and Efficacy of IBA Proton Therapy System PROTEUS® PLUS (Hebei) Proton Beam Therapy (PBT) - Solid Tumor, Adult | Not applicable | Active not recruiting | Ion Beam Applications | 47 | 2025-04-29 | 2026-02-27 |
| Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations TYRA-430 - Metastatic Hepatocellular Carcinoma, Solid Tumors | Phase 1 | Recruiting | Tyra Biosciences, Inc | 125 | 2025-04-24 | 2026-10-14 |
| Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors BL-M17D1 - Breast Cancer Stage III, HER2-positive Metastatic Breast Cancer | Phase 1 | Terminated | SystImmune Inc. | 3 | 2025-04-10 | 2026-09-22 |
| BBO-11818 in Adult Subjects With KRAS Mutant Cancer BBO-11818, Pembrolizumab, Platinum chemotherapy (cisplatin or carboplatin) - Non-Small Cell Lung Cancer, NSCLC | Phase 1 | Recruiting | TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) | 665 | 2025-03-31 | 2026-06-02 |
| A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours ATTR-01 - Solid Tumor, Adult | Phase 1 / Phase 2 | Recruiting | Accession Therapeutics Limited | 72 | 2025-03-21 | 2026-05-22 |
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PMID 12001988, PMID 17704903, PMID 19906081, PMID 19917863, PMID 20061178, PMID 20233873, PMID 20336386, PMID 20374484, PMID 20490982, PMID 20737573, PMID 21153378, PMID 21909917, PMID 21926464, PMID 22162570, PMID 23456602, PMID 24956510, PMID 25013744, PMID 26883450, PMID 2801858, PMID 28445469, PMID 29656895, PMID 30082340, PMID 31560935, PMID 32017652, PMID 32182156, PMID 32186413, PMID 32750212, PMID 33464545, PMID 33479856, PMID 33654117, PMID 33723724, PMID 33888901, PMID 33947698, PMID 34038589, PMID 34330842, PMID 34407972, PMID 34482636, PMID 34965951, PMID 34998048, PMID 35397434, PMID 35658948, PMID 35660797, PMID 35892341, PMID 35950603, PMID 36545256, PMID 37124504, PMID 37214210, PMID 37222204, PMID 38008031, PMID 3808620
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