14 completed, 8 active not recruiting, 4 terminated, 3 recruiting. 17 Phase 1, 5 Not applicable, 3 Phase 2, 2 Early Phase 1, 1 Phase 3.
Follow Solid Neoplasm: new trials by email Literature Review of Solid Neoplasm trials Research Report on Solid Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Weight Management in Obese Cancer Patients During Curative Active Treatment Multimodal weight management program - Obesity, Solid Neoplasm | Not applicable | Recruiting | Institut d'Investigació Biomèdica de Bellvitge | 50 | 2025-07-22 | 2025-07-28 |
| Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues Computed Tomography, Gallium Ga 68 FAPi-46, Gallium Ga 68-labeled PSMA-11 - Breast Carcinoma, Colon Carcinoma | Early Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 29 | 2019-11-05 | 2026-08-21 |
| Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia Larotrectinib Sulfate - Central Nervous System Neoplasm, Infantile Fibrosarcoma | Phase 2 | Active not recruiting | Children's Oncology Group | 33 | 2019-10-25 | 2025-12-02 |
| Nozin in Preventing Respiratory Viral Infections in Patients Undergoing Stem Cell Transplant, PREV-NOSE STUDY Nozin, Best Practice - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Phase 1 | Terminated | Fred Hutchinson Cancer Center | 10 | 2019-09-03 | 2024-11-08 |
| Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting Survey Administration - Breast Carcinoma, Colorectal Carcinoma | Withdrawn | ECOG-ACRIN Cancer Research Group | 2019-01-08 | 2026-09-15 | ||
| Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 Fluorthanatrace - Breast Carcinoma, Fallopian Tube Carcinoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 300 | 2018-12-18 | 2026-10-06 |
| Financial Navigation Program Intervention in Supporting Patients With Solid Tumors and Their Caregivers Educational Intervention, Questionnaire Administration, Quality-of-Life Assessment - Caregiver, Solid Neoplasm | Not applicable | Completed | Fred Hutchinson Cancer Center | 30 | 2017-11-15 | 2019-05-20 |
| Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Cabozantinib, Cabozantinib S-malate, Pharmacological Study - Adrenal Cortical Carcinoma, Alveolar Soft Part Sarcoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 109 | 2017-05-18 | 2026-08-28 |
| Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors Carboplatin, Cisplatin, Palbociclib - Solid Neoplasm, Stage III Pancreatic Cancer | Phase 1 | Completed | Emory University | 71 | 2016-10-24 | 2023-10-10 |
| Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration - Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 60 | 2016-08-29 | 2026-10-07 |
| Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Laboratory Biomarker Analysis, Pharmacological Study, Talazoparib - Estrogen Receptor Negative, Head and Neck Squamous Cell Carcinoma | Phase 1 | Withdrawn | National Cancer Institute (NCI) | 2016-06-01 | 2017-04-24 | |
| Movement Tracking Devices to Monitor Physical Activity in Patients Undergoing Chemotherapy Accelerometer, Laboratory Biomarker Analysis, Physical Activity Measurement - Solid Neoplasm | Not applicable | Completed | University of Southern California | 41 | 2016-05-06 | 2025-06-25 |
| UWCCC Molecular Tumor Board Registry PMMTB (Precision Medicine Molecular Tumor Board) - Hematologic Neoplasms, Solid Neoplasm | Recruiting | University of Wisconsin, Madison | 10000 | 2016-03-30 | 2026-04-13 | |
| TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors Cyclophosphamide, Laboratory Biomarker Analysis, Pegfilgrastim - Colorectal Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 1 | Terminated | Mayo Clinic | 4 | 2016-02-05 | 2018-09-05 |
| Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations Laboratory Biomarker Analysis, Nanoparticle Albumin-Bound Rapamycin, Quality-of-Life Assessment - Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma | Early Phase 1 | Completed | Mayo Clinic | 2 | 2016-01-01 | 2019-06-06 |
| An Investigational Device (Millar Mikro-Tip Catheter) and Imaging Scan (Shear Wave Elastography) in Measuring Tumor Pressure and Stiffness in Patients With Solid Tumors Undergoing Ultrasound-Guided Biopsy Shear Wave Elastography, Tumor Interstitial Fluid Pressure Measurement - Solid Neoplasm | Not applicable | Completed | M.D. Anderson Cancer Center | 27 | 2015-12-29 | 2026-01-13 |
| Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery Ilorasertib, Laboratory Biomarker Analysis - Metastatic Malignant Neoplasm, Solid Neoplasm | Phase 1 | Completed | University of Chicago | 12 | 2015-09-08 | 2019-04-22 |
| Geriatric Assessment in Predicting Chemotherapy Toxicity and Vulnerabilities in Older Patients With Cancer Comprehensive Geriatric Assessment, Quality-of-Life Assessment, Questionnaire Administration - Solid Neoplasm | Not applicable | Active not recruiting | City of Hope Medical Center | 600 | 2015-08-17 | 2026-10-20 |
| Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases Whole brain radiation therapy with hippocampal avoidance, Memantine, Whole brain radiation therapy - Cognitive Impairment, Metastatic Malignant Neoplasm in the Brain | Phase 3 | Completed | NRG Oncology | 518 | 2015-07-01 | 2026-09-10 |
| Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors or Lymphoma Gemcitabine Hydrochloride, Laboratory Biomarker Analysis, Pharmacological Study - Lymphoma, Solid Neoplasm | Phase 1 | Terminated | Roswell Park Cancer Institute | 10 | 2015-05-01 | 2022-07-25 |
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Breast Neoplasms (7) · Ovarian Neoplasms (7) · Carcinoma, Renal Cell (5) · Colorectal Neoplasms (4) · Pancreatic Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Central Nervous System Neoplasms (3) · Fallopian Tube Neoplasms (3) · Melanoma (3) · Sarcoma (3) · Hematologic Neoplasms (2) · Lung Neoplasms (2) · Prostatic Neoplasms (2) · Stomach Neoplasms (2) · Triple Negative Breast Neoplasms (2)
Neoplasms (19) · Neoplasms by Site (17) · Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Urogenital Diseases (11) · Endocrine Gland Neoplasms (10) · Endocrine System Diseases (10) · Neoplasms by Histologic Type (10) · Urogenital Neoplasms (10) · Digestive System Diseases (9) · Digestive System Neoplasms (9) · Skin Diseases (9) · Skin and Connective Tissue Diseases (9) · Breast Diseases (8) · Male Urogenital Diseases (8)
veliparib (3) · Bevacizumab (2) · Cyclophosphamide (2) · Disulfides (2) · Fluorodeoxyglucose F18 (2) · Immunoglobulin G (2) · Magnetic Resonance Spectroscopy (2) · 68Ga-DKFZ-PSMA-11 (1) · ARQ 197 (1) · AZD 6244 (1) · Carboplatin (1) · Cisplatin (1) · Cyclosporine (1) · Cyclosporins (1) · Doxorubicin (1)
National Cancer Institute (NCI) (12) · M.D. Anderson Cancer Center (4) · Fred Hutchinson Cancer Center (2) · Mayo Clinic (2) · Children's Oncology Group (1) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1) · Emory University (1) · Institut d'Investigació Biomèdica de Bellvitge (1) · Jonsson Comprehensive Cancer Center (1) · NRG Oncology (1) · Roswell Park Cancer Institute (1) · University of Chicago (1) · University of Southern California (1) · University of Wisconsin, Madison (1)
United States (29) · Canada (5) · Spain (1)
Carmen Escalante (1) · Christopher H Lieu (1) · Daneng Li (1) · Daniel Renouf (1) · Dustin Deming, MD (1) · Jeremie Calais, MD (1) · Jing Li (1) · Jorge Nieva (1) · Julia Trosman (1) · Julian Molina (1) · Keith C Bible (1) · Lakshmi Nayak (1) · Leonard Appleman (1) · Lilie L Lin (1) · Lorena Arribas, PhD, MsC, RD (1)
PMID 31401903, PMID 32058845, PMID 34164713, PMID 34591080, PMID 36512649, PMID 39208372, PMID 39652801, PMID 40973049, PMID 41101974, PMID 42343485
P30CA015083 (5), UM1CA186690 (4), UM1CA186716 (4), P30CA016672 (3), U01CA069912 (3), UM1CA186644 (3), UM1CA186686 (3), UM1CA186709 (3), UM1CA186717 (3), P30CA047904 (2), U01CA062490 (2), U01CA099168 (2), U01CA132194 (2), U10CA180886 (2), UM1CA186712 (2)