7 completed, 1 not yet recruiting, 1 unknown. 9 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 7, Not yet recruiting 1, Unknown 1 |
Follow Sarcoma, Kaposi: new trials by email Literature Review of Sarcoma, Kaposi trials Research Report on Sarcoma, Kaposi
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma Pegylated liposomal doxorubicin, Paclitaxel - Kaposi Sarcoma, HIV-1-infection | Phase 3 | Not yet recruiting | AIDS Malignancy Consortium | 130 | 2026-09-01 | 2026-01-23 |
| Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma efavirenz/emtricitabine/tenofovir disoproxil fumarate, etoposide - HIV-1 Infection, Kaposi's Sarcoma | Phase 3 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 192 | 2011-11-18 | 2019-11-14 |
| A Study of AZT in HIV-Infected Patients With AIDS-Related Kaposi's Sarcoma Zidovudine - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 240 | 2021-11-04 | |
| Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma. Doxorubicin hydrochloride (liposomal) - Sarcoma, Kaposi, HIV Infections | Phase 3 | Completed | Sequus Pharmaceuticals | 2005-06-24 | ||
| A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma Doxorubicin hydrochloride (liposomal), Bleomycin sulfate, Vincristine sulfate - Sarcoma, Kaposi, HIV Infections | Phase 3 | Unknown | Sequus Pharmaceuticals | 225 | 2005-06-24 | |
| Safety and Effectiveness of an Experimental Drug, IM862, in Treating Kaposi's Sarcoma in AIDS Patients IM862 - Sarcoma, Kaposi, HIV Infections | Phase 3 | Completed | Cytran | 200 | 2005-06-24 | |
| A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma. Daunorubicin (liposomal), Bleomycin sulfate, Vincristine sulfate - Sarcoma, Kaposi, HIV Infections | Phase 3 | Completed | Nexstar Pharmaceuticals | 2005-06-24 | ||
| Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma Doxorubicin hydrochloride (liposomal), Bleomycin sulfate, Vincristine sulfate - Sarcoma, Kaposi, HIV Infections | Phase 3 | Completed | Sequus Pharmaceuticals | 220 | 2005-06-24 | |
| A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcoma Doxorubicin hydrochloride (liposomal) - Sarcoma, Kaposi, HIV Infections | Phase 3 | Completed | Sequus Pharmaceuticals | 2005-06-24 |
Acquired Immunodeficiency Syndrome (7) · HIV Infections (7) · AIDS-Related Opportunistic Infections (2) · AIDS-related Kaposi sarcoma (1)
DNA Virus Infections (9) · Herpesviridae Infections (9) · Infections (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Connective and Soft Tissue (9) · Neoplasms, Vascular Tissue (9) · Sarcoma (9) · Virus Diseases (9) · Blood-Borne Infections (8) · Communicable Diseases (8) · Genital Diseases (8) · Immune System Diseases (8) · Immunologic Deficiency Syndromes (8) · Lentivirus Infections (8)
Doxorubicin (5) · Liposomes (4) · Bleomycin (3) · Vincristine (3) · Daunorubicin (1) · Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Etoposide (1) · Paclitaxel (1) · Zidovudine (1) · liposomal doxorubicin (1)
Sequus Pharmaceuticals (4) · AIDS Malignancy Consortium (1) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Cytran (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Nexstar Pharmaceuticals (1)
United States (7) · Australia (1) · Belgium (1) · Brazil (1) · Canada (1) · Kenya (1) · Malawi (1) · Peru (1) · South Africa (1) · Uganda (1)
Ariela Noy (1) · David Scadden (1) · Mina C Hosseinipour, M.D. (1) · Parkash Gill (1) · Susan Krown, MD (1) · Thomas B Campbell, M.D. (1) · Valentine FT (1)
PMID 29365083, PMID 31520741, PMID 37368929, PMID 41286911
U01AI068636 (1), U01CA121947 (1)