4 completed, 1 not yet recruiting, 1 recruiting, 1 unknown. 3 Phase 3, 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Rifampicin Resistant Tuberculosis: new trials by email Literature Review of Rifampicin Resistant Tuberculosis trials Research Report on Rifampicin Resistant Tuberculosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BLMZ Chinese Cohort BLMZ - Rifampicin Resistant Tuberculosis, Pulmonary Tuberculosis | Phase 3 | Not yet recruiting | Beijing Chest Hospital | 120 | 2025-12-01 | 2025-12-08 |
| Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis Pretomanid, Optimized background regimen (OBR) for multidrug-resistant TB (MDR-TB) - Tuberculosis, Rifampicin Resistant Tuberculosis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 32 | 2023-10-03 | 2026-09-28 |
| Innovating(IN) Shorter(S), All- Oral, Precised(P), Individualized(I) Treatment Regimen(RE) for Rifampicin Resistant Tuberculosis(INSPIRE-TB) Bdq(Lzd)+Lfx(Mfx)+Cfz(Cs)+Pto+E+H+Z, A1, A2a - Multidrug Resistant Tuberculosis, Rifampicin Resistant Tuberculosis | Phase 3 | Recruiting | Huashan Hospital | 1050 | 2022-05-23 | 2025-04-06 |
| Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment Trial WGS DST strategy - Rifampicin Resistant Tuberculosis, Drug-resistant Tuberculosis | Not applicable | Unknown | Universiteit Antwerpen | 248 | 2021-09-21 | 2021-10-15 |
| Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care Bedaquiline Oral Tablet, Linezolid Oral Tablet, Delamanid in Oral Dosage Form - Tuberculosis, Pre-XDR-TB | Phase 3 | Completed | Wits Health Consortium (Pty) Ltd | 402 | 2019-08-22 | 2024-08-28 |
| GeneXpert Performance Evaluation for Linkage to Tuberculosis Care GeneXpert I, Process re-design, Performance Feedback - Tuberculosis, Pulmonary, Rifampicin Resistant Tuberculosis | Not applicable | Completed | University of California, San Francisco | 10644 | 2018-10-22 | 2025-02-18 |
| Line Probe Assay Evaluation Study YD REBA MTB-MDR, Hain Genotype MTBDRplus V1, Hain Genotype MTBDRplus V2 - Multidrug-Resistant Tuberculosis, Isoniazid Resistant Pulmonary Tuberculosis | Completed | Foundation for Innovative New Diagnostics, Switzerland | 888 | 2015-03-01 | 2026-09-03 |
Tuberculosis, Multidrug-Resistant (5) · Tuberculosis (4) · Tuberculosis, Pulmonary (4) · Extensively Drug-Resistant Tuberculosis (1)
Actinomycetales Infections (7) · Bacterial Infections (7) · Bacterial Infections and Mycoses (7) · Gram-Positive Bacterial Infections (7) · Infections (7) · Mycobacterium Infections (7) · Lung Diseases (4) · Respiratory Tract Diseases (4) · Respiratory Tract Infections (4) · Tuberculosis (3)
A(2)C (1) · Clofazimine (1) · Dosage Forms (1) · Levofloxacin (1) · Linezolid (1) · OPC-67683 (1) · bedaquiline (1) · pretomanid (1)
Beijing Chest Hospital (1) · Foundation for Innovative New Diagnostics, Switzerland (1) · Huashan Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Universiteit Antwerpen (1) · University of California, San Francisco (1) · Wits Health Consortium (Pty) Ltd (1)
South Africa (3) · China (2) · Brazil (1) · Thailand (1) · Uganda (1)
Adithya Cattamanchi, MD (1) · Annelies Van Rie, PhD, MD (1) · Ethel Weld (1) · Francesca M Conradie (1) · Gavin Churchyard, PhD, MD (1) · Rob M Warren, PhD (1) · Salome Charalambous, PhD (1) · Wenhong Zhang, PHD (1)
PMID 32316993, PMID 34936740, PMID 36209235, PMID 42026006, PMID 42341301
R01HL130192 (1)