3 recruiting, 2 not yet recruiting, 1 completed. 4 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 2, Completed 1, Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Refractory Constipation: new trials by email Literature Review of Refractory Constipation trials Research Report on Refractory Constipation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder Features Fluoxetine, Placebo - Refractory Constipation, Somatic Symptom Disorder (DSM-5) | Phase 2 | Not yet recruiting | Zhifeng Zhao, PhD | 194 | 2026-09-01 | 2026-09-02 |
| The Role of Anorectal Manometry in Pediatric Chronic Refractory Constipation High resolution anorectal manometry using a multiuse water perfused catheter - Refractory Constipation, Fecal Incontinence in Children | Not applicable | Not yet recruiting | Assiut University | 54 | 2026-01-01 | 2025-12-18 |
| Optimization of taVNS Intervention Strategies for Refractory Constipation transcutaneous auricular vagus nerve stimulation, Placebo - Refractory Constipation | Not applicable | Recruiting | Xijing Hospital of Digestive Diseases | 100 | 2025-09-01 | 2026-01-15 |
| Transcranial Alternating Current Stimulation for Refractory Constipation With Somatic Symptom Disorder Transcranial Alternating Current Stimulation, Placebo - Functional Constipation (FC), Somatic Symptom Disorder (DSM-5) | Not applicable | Recruiting | Xijing Hospital of Digestive Diseases | 60 | 2025-08-20 | 2026-01-09 |
| Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation BOLD-fMRI, Regular treatment of functional constipation, fluoxetine - Constipation - Functional, Refractory Constipation | Recruiting | Xijing Hospital of Digestive Diseases | 150 | 2023-11-01 | 2025-07-24 | |
| Fluoxetine for Refractory Constipation Fluoxetine, Polyethylene Glycol 400 0.4% - Refractory Constipation | Not applicable | Completed | Zhifeng Zhao, PhD | 316 | 2020-01-01 | 2025-06-18 |
Constipation (6) · Fecal Incontinence (1) · Medically Unexplained Symptoms (1)
Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Signs and Symptoms, Digestive (6) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Intestinal Diseases (1) · Rectal Diseases (1)
Fluoxetine (3) · Polyethylene Glycols (1) · Transcranial Direct Current Stimulation (1)
Xijing Hospital of Digestive Diseases (3) · Zhifeng Zhao, PhD (2) · Assiut University (1)
China (4) · Egypt (1)
Qingchuan Zhao, Prof. (2) · Naglaa H. Ibrahim, Professor (1) · Naglaa S. Mohamed, A. professor (1) · Rehab I. Hassan, Lecturer (1)