4 active not recruiting. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 4 |
Follow Recurrent Medulloblastoma: new trials by email Literature Review of Recurrent Medulloblastoma trials Research Report on Recurrent Medulloblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine administered intravenously (RNA loaded lipid particles, RNA-LPs) - Recurrent Medulloblastoma | Phase 1 | Active not recruiting | University of Florida | 24 | 2026-04-24 | 2026-09-29 |
| Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors Biospecimen Collection, Magnetic Resonance Imaging, Savolitinib - Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Malignant Glioma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 41 | 2018-11-27 | 2026-07-30 |
| PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma PEP-CMV - Recurrent Medulloblastoma, Recurrent Brain Tumor, Childhood | Phase 1 | Active not recruiting | Daniel Landi | 30 | 2018-06-29 | 2026-06-18 |
| Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma Biospecimen Collection, Conventional Magnetic Resonance Imaging, Diffusion Tensor Imaging - Constitutional Mismatch Repair Deficiency Syndrome, Lynch Syndrome | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 71 | 2015-06-03 | 2026-07-20 |
Medulloblastoma (4) · Glioma (3) · Brain Neoplasms (2) · Diffuse Intrinsic Pontine Glioma (2) · Central Nervous System Neoplasms (1) · Colorectal Neoplasms, Hereditary Nonpolyposis (1) · Ependymoma (1) · Familial ependymoma (1) · Turcot syndrome (1)
Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Neuroectodermal Tumors, Primitive (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Neoplasms by Site (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Brain Stem Neoplasms (2) · Central Nervous System Neoplasms (2)
Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · 1-(1-(imidazo(1,2-a)pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-(1,2,3)triazolo(4,5-b)pyrazine (1) · Diffusion Tensor Imaging (1) · Lysosomal Membrane Proteins (1) · Phantoms, Imaging (1) · X-Rays (1) · pembrolizumab (1)
National Cancer Institute (NCI) (2) · Daniel Landi (1) · University of Florida (1)
United States (4) · Canada (2)
Daniel Landi, MD (1) · Elias Sayour, MD, PhD (1) · Eugene I Hwang (1) · Ralph Salloum (1) · Sabine Mueller, MD, PhD (1)
UM1CA081457 (2)