11 completed, 3 terminated, 1 withdrawn. 7 Phase 2, 4 Phase 1, 3 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 4, Terminated 3 |
| Phase 1 | 4 | Completed 4 |
| Not applicable | 3 | Completed 2, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow Recurrent Malignant Testicular Germ Cell Tumor: new trials by email Literature Review of Recurrent Malignant Testicular Germ Cell Tumor trials Research Report on Recurrent Malignant Testicular Germ Cell Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors palifosfamide - Adult Central Nervous System Germ Cell Tumor, Adult Teratoma | Phase 2 | Terminated | Indiana University | 5 | 2013-02-01 | 2015-07-02 |
| Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant management of therapy complications, musculoskeletal complications management/prevention - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Withdrawn | Roswell Park Cancer Institute | 2012-05-01 | 2012-07-09 | |
| Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant supersaturated calcium phosphate rinse, placebo, questionnaire administration - Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 226 | 2011-03-01 | 2019-09-17 |
| Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload deferasirox - Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Terminated | City of Hope Medical Center | 1 | 2010-07-01 | 2019-06-18 |
| Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer PD-0332991 - Adult Solid Tumor, Adenocarcinoma of the Colon | Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 304 | 2009-10-01 | 2021-03-11 |
| Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Alvocidib Hydrochloride, Fluorouracil, Leucovorin Calcium - Recurrent Extragonadal Seminoma, Recurrent Malignant Extragonadal Germ Cell Tumor | Phase 2 | Completed | National Cancer Institute (NCI) | 36 | 2009-06-01 | 2017-03-10 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Carboplatin, Filgrastim, Ifosfamide - Childhood Extracranial Germ Cell Tumor, Childhood Extragonadal Malignant Germ Cell Tumor | Phase 2 | Completed | Children's Oncology Group | 20 | 2007-11-05 | 2018-08-29 |
| Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor busulfan, melphalan, topotecan hydrochloride - Solid Tumor, Adult Central Nervous System Germ Cell Tumor | Phase 1 | Completed | City of Hope Medical Center | 25 | 2007-02-26 | 2025-03-20 |
| High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors etoposide, cyclophosphamide, carmustine - Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission | Not applicable | Completed | Roswell Park Cancer Institute | 174 | 2006-06-29 | 2021-04-22 |
| Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant lithium carbonate, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Completed | Fred Hutchinson Cancer Center | 20 | 2006-06-01 | 2017-03-07 |
| Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer ipilimumab, therapeutic allogeneic lymphocytes - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 | Completed | National Cancer Institute (NCI) | 21 | 2003-04-01 | 2013-03-27 |
| Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer imatinib mesylate, therapeutic conventional surgery, laboratory biomarker analysis - Ovarian Dysgerminoma, Recurrent Malignant Testicular Germ Cell Tumor | Phase 2 | Terminated | National Cancer Institute (NCI) | 32 | 2002-06-01 | 2013-01-17 |
| Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer recombinant fowlpox-CEA(6D)/TRICOM vaccine, sargramostim, recombinant fowlpox GM-CSF vaccine adjuvant - Adenocarcinoma of the Colon, Adenocarcinoma of the Gallbladder | Phase 1 | Completed | National Cancer Institute (NCI) | 48 | 2001-11-01 | 2013-01-25 |
| Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu recombinant interleukin-12, ABI-007/carboplatin/trastuzumab - Advanced Adult Primary Liver Cancer, Anaplastic Thyroid Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 15 | 1999-08-01 | 2013-02-28 |
Testicular Neoplasms (15) · Breast Neoplasms (8) · Burkitt Lymphoma (7) · Neuroblastoma (7) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (7) · Carcinoma, Ovarian Epithelial (6) · Congenital Abnormalities (6) · Hodgkin Disease (6) · Leukemia, Lymphocytic, Chronic, B-Cell (6) · Leukemia, Myeloid, Acute (6) · Lymphoma, Follicular (6) · Lymphoma, Large B-Cell, Diffuse (6) · Lymphoma, Large-Cell, Immunoblastic (6) · Lymphoma, Mantle-Cell (6) · Lymphoma, Non-Hodgkin (6)
Endocrine Gland Neoplasms (15) · Endocrine System Diseases (15) · Genital Diseases (15) · Genital Diseases, Male (15) · Genital Neoplasms, Male (15) · Gonadal Disorders (15) · Male Urogenital Diseases (15) · Neoplasms by Site (15) · Testicular Diseases (15) · Urogenital Diseases (15) · Urogenital Neoplasms (15) · Neoplasms (14) · Neoplasms by Histologic Type (14) · Neoplasms, Germ Cell and Embryonal (13) · Neoplasms, Nerve Tissue (10)
Busulfan (2) · Carboplatin (2) · Filgrastim (2) · Granulocyte Colony-Stimulating Factor (2) · Ifosfamide (2) · Melphalan (2) · Bone Marrow Transplantation (1) · CTLA-4 Antigen (1) · Carmustine (1) · Cyclophosphamide (1) · Deferasirox (1) · Etoposide (1) · Fluorouracil (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Imatinib Mesylate (1)
National Cancer Institute (NCI) (5) · Children's Oncology Group (2) · City of Hope Medical Center (2) · Fred Hutchinson Cancer Center (2) · Roswell Park Cancer Institute (2) · Abramson Cancer Center at Penn Medicine (1) · Indiana University (1)
United States (14) · Australia (2) · Canada (2) · Puerto Rico (1)
Philip McCarthy (2) · Anna Pawlowska, MD (1) · Carlos Rodriguez-Galindo (1) · Christopher Ryan (1) · Darren Feldman (1) · Ewa Carrier (1) · Lawrence H Einhorn, MD (1) · Leona Holmberg (1) · Margaret von Mehren (1) · Nathaniel Treister, MD (1) · Paul Martin (1) · Peter ODwyer (1) · Vinod Pullarkat, MD (1) · William Carson (1)
PMID 18974373, PMID 28817727, PMID 32641862, PMID 32692450
N01CM00071 (1), N01CM62206 (1), P30CA008748 (1), P30CA016056 (1), R01CA093891 (1), U01CA062491 (1), U01CA062505 (1), U01CA069856 (1), U01CA069912 (1), U01CA076576 (1), U01CA099168 (1), U10CA031946 (1), U10CA095861 (1), U10CA098543 (1)