2 terminated, 1 completed, 1 recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Terminated 2, Completed 1, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Recurrent Childhood Gliosarcoma: new trials by email Literature Review of Recurrent Childhood Gliosarcoma trials Research Report on Recurrent Childhood Gliosarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling Functional Precision Medicine - Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 1 | Recruiting | Florida International University | 65 | 2023-02-22 | 2026-08-26 |
| Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors palbociclib isethionate, pharmacological study, laboratory biomarker analysis - Childhood Choroid Plexus Tumor, Childhood Ependymoblastoma | Phase 1 | Terminated | Pediatric Brain Tumor Consortium | 35 | 2014-12-08 | 2021-03-02 |
| Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery oncolytic HSV-1716, dexamethasone, therapeutic conventional surgery - Recurrent Childhood Anaplastic Astrocytoma, Recurrent Childhood Anaplastic Oligoastrocytoma | Phase 1 | Terminated | Pediatric Brain Tumor Consortium | 2 | 2013-12-01 | 2016-05-30 |
| Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors lapatinib ditosylate, therapeutic conventional surgery, laboratory biomarker analysis - Recurrent Childhood Anaplastic Astrocytoma, Recurrent Childhood Brain Stem Glioma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 52 | 2004-10-01 | 2014-05-23 |
Astrocytoma (3) · Glioblastoma (3) · Oligodendroglioma (3) · Familial ependymoma (2) · Medulloblastoma (2) · Neoplasms, Neuroepithelial (2) · Choroid Plexus Neoplasms (1) · Dendritic Cell Sarcoma, Interdigitating (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Neoplasms by Histologic Type (4) · Glioma (3) · Neoplasms (3) · Neoplasms, Germ Cell and Embryonal (3) · Neoplasms, Glandular and Epithelial (3) · Neoplasms, Nerve Tissue (3) · Neuroectodermal Tumors (3) · Neuroectodermal Tumors, Primitive (2) · Bone Marrow Diseases (1) · Brain Diseases (1) · Brain Neoplasms (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Cerebral Ventricle Neoplasms (1) · Chronic Disease (1)
2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Lapatinib (1) · Magnetic Resonance Spectroscopy (1) · N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl-6-(5-((methylsulfonyl)ethyl)aminomethyl)-2-furyl)-4-quinazolinamine (1) · palbociclib (1)
Pediatric Brain Tumor Consortium (2) · Florida International University (1) · National Cancer Institute (NCI) (1)
United States (4)
David Van Mater, MD (1) · Diana Azzam (1) · Maggie Fader (1) · Mariko DeWire (1) · Maryam Fouladi (1)
U01CA081457 (3), U54MD012393 (1)