45 completed. 45 Phase 2, 12 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 45 | Completed 45 |
| Phase 1 | 12 | Completed 12 |
Follow Recurrent Adult Diffuse Large Cell Lymphoma: new trials by email Literature Review of Recurrent Adult Diffuse Large Cell Lymphoma trials Research Report on Recurrent Adult Diffuse Large Cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20 anti-CD19/20-CAR vector-transduced T cells - Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Chinese PLA General Hospital | 100 | 2017-04-01 | 2020-09-02 |
| Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies vorinostat, tacrolimus, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | National Cancer Institute (NCI) | 12 | 2013-06-01 | 2018-07-24 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Belinostat and Yttrium Y 90 Ibritumomab Tiuxetan in Patients W/Relapsed Aggressive B-Cell NHL belinostat, rituximab, yttrium Y 90 ibritumomab tiuxetan - Anaplastic Large Cell Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma | Phase 2 | Completed | University of Arizona | 5 | 2012-08-31 | 2018-08-28 |
| CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant allogeneic cytomegalovirus-specific cytotoxic T lymphocytes - Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 1 | 2012-04-01 | 2017-02-15 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors Bendamustine Hydrochloride, Pharmacological Study, Rituximab - Adult B Acute Lymphoblastic Leukemia, Adult Nasal Type Extranodal NK/T-Cell Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 43 | 2011-07-01 | 2019-12-16 |
| Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma panobinostat, laboratory biomarker analysis, western blotting - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | Mayo Clinic | 41 | 2011-01-17 | 2022-05-24 |
| Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma everolimus, lenalidomide, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 58 | 2011-01-10 | 2020-10-22 |
| Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies deferasirox, laboratory biomarker analysis, enzyme-linked immunosorbent assay - Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Wake Forest University Health Sciences | 16 | 2011-01-01 | 2018-09-07 |
| Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Akt inhibitor MK2206, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2010-12-01 | 2020-11-04 |
| Bendamustine Hydrochloride, Rituximab, Etoposide, and Carboplatin in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma or Hodgkin Lymphoma Bendamustine Hydrochloride, Carboplatin, Rituximab - Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma | Phase 1 / Phase 2 | Completed | University of Washington | 48 | 2010-09-01 | 2018-12-05 |
| Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multiple Myeloma bendamustine hydrochloride, dexamethasone, filgrastim - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Completed | University of Washington | 43 | 2010-08-01 | 2017-05-24 |
| Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma panobinostat, everolimus, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 124 | 2009-06-01 | 2020-03-10 |
| Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 63 | 2009-02-01 | 2018-01-02 |
| Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant ondansetron, survey administration, management of therapy complications - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 49 | 2008-08-08 | 2017-05-23 |
| Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma vorinostat, rituximab, ifosfamide - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | University of Washington | 29 | 2007-12-01 | 2017-05-25 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer beclomethasone dipropionate, placebo, tacrolimus - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 140 | 2007-04-01 | 2021-02-03 |
Showing 20 of 45. Sign in to see all of them.
Lymphoma, Large B-Cell, Diffuse (45) · Lymphoma, Mantle-Cell (39) · Lymphoma, Follicular (36) · Burkitt Lymphoma (33) · Leukemia, Lymphocytic, Chronic, B-Cell (33) · Lymphoma, B-Cell, Marginal Zone (33) · Lymphoma, Non-Hodgkin (31) · Waldenstrom Macroglobulinemia (31) · Lymphoma, Large-Cell, Immunoblastic (30) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (30) · Lymphoma, Large-Cell, Anaplastic (27) · Hodgkin Disease (25) · Mycosis Fungoides (23) · Sezary Syndrome (23) · Lymphoma, T-Cell, Cutaneous (22)
Hemic and Lymphatic Diseases (45) · Immune System Diseases (45) · Immunoproliferative Disorders (45) · Lymphatic Diseases (45) · Lymphoma (45) · Lymphoma, B-Cell (45) · Lymphoproliferative Disorders (45) · Neoplasms by Histologic Type (45) · Neoplasms (44) · Hematologic Diseases (37) · Leukemia (36) · Leukemia, Lymphoid (36) · Blood Protein Disorders (33) · Cardiovascular Diseases (33) · Chronic Disease (33)
Peripheral Blood Stem Cell Transplantation (11) · Rituximab (11) · Mycophenolic Acid (10) · Whole-Body Irradiation (10) · fludarabine phosphate (10) · Cyclosporine (9) · Tacrolimus (6) · Cyclophosphamide (5) · Etoposide (5) · Carboplatin (4) · Methotrexate (4) · ibritumomab tiuxetan (4) · merphos (4) · Bendamustine Hydrochloride (3) · Busulfan (3)
National Cancer Institute (NCI) (16) · Fred Hutchinson Cancer Center (15) · Mayo Clinic (4) · University of Washington (3) · Case Comprehensive Cancer Center (2) · Chinese PLA General Hospital (1) · Roswell Park Cancer Institute (1) · University of Arizona (1) · University of Chicago (1) · Wake Forest University Health Sciences (1)
United States (43) · Italy (5) · Germany (2) · Canada (1) · China (1) · Denmark (1)
Ajay Gopal (5) · Brenda Sandmaier (4) · David Maloney (3) · Sonali Smith (3) · Anas Younes (2) · Alison Stopeck (1) · Barbara Pro (1) · Brenda Cooper (1) · Brenda Cooper, MD (1) · Cameron Turtle (1) · Craig Reeder, M.D. (1) · Daniel O. Persky, MD (1) · David Scadden (1) · George Chen (1) · Hillard Lazarus (1)
PMID 32499241, PMID 34515338, PMID 19900571, PMID 20837940, PMID 21508413, PMID 25085357, PMID 26213141, PMID 26764356, PMID 28314788, PMID 28869931, PMID 30454872, PMID 30596402, PMID 31481800, PMID 41804087
P30CA015704 (10), N01CM62202 (4), P01CA018029 (4), N01CM62201 (3), P01CA078902 (3), N01CM17003 (2), P30CA014599 (2), P30CA015083 (2), U10CA032102 (2), N01CM00039 (1), N01CM17107 (1), N01CM62203 (1), P01CA044991 (1), P30CA008748 (1), P30CA016672 (1)