14 completed. 14 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 14 |
| Phase 2 | 2 | Completed 2 |
Follow Prolapse: new trials by email Literature Review of Prolapse trials Research Report on Prolapse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft - Rectocele; Female, Pelvic Organ Prolapse | Phase 3 | Completed | Ain Shams Maternity Hospital | 25 | 2023-11-01 | 2025-12-02 |
| Lidocaine for Pessary Check Pain Reduction Lidocaine Hcl 2% Jelly, Placebo Jelly - Pelvic Organ Prolapse, Stress Urinary Incontinence | Phase 3 | Completed | University of South Florida | 66 | 2022-09-08 | 2023-12-14 |
| Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients Alfacalcidol 0.0005 MG, Placebo - Pelvic Organ Prolapse | Phase 3 | Completed | Universitas Padjadjaran | 48 | 2020-11-01 | 2022-08-17 |
| Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery. - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University of New Mexico | 137 | 2019-07-15 | 2023-07-10 |
| Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery Placebo oral capsule, Tamsulosin - Urinary Retention, Lower Urinary Tract Symptoms | Phase 2 / Phase 3 | Completed | University Hospitals Cleveland Medical Center | 132 | 2018-08-01 | 2021-11-08 |
| Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP Dexamethasone, Placebo - Pelvic Organ Prolapse, PONV | Phase 3 | Completed | TriHealth Inc. | 63 | 2013-02-01 | 2016-04-21 |
| Pelvic Organ Prolapse Repair Plus Mini-Sling Versus Pelvic Organ Prolapse Repair Alone POP repair plus mini-sling, POP repair - Pelvic Organ Prolapse, Urinary Incontinence | Phase 3 | Completed | University Of Perugia | 50 | 2011-06-01 | 2014-05-20 |
| Surgical Correction of Pelvic Organ Prolapse Colposacropexy - Pelvic Organ Prolapse | Phase 3 | Completed | University Of Perugia | 40 | 2010-08-01 | 2014-05-20 |
| The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse Vaginal conjugated estrogen cream 0.5gm, Vaginal conjugated estrogen cream 1.0gm - Pelvic Organ Prolapse, Vaginal Atrophy | Phase 3 | Completed | TriHealth Inc. | 54 | 2008-12-01 | 2015-05-27 |
| Safety Study of Pelvic Organ Prolapse Repair Using Transvaginal Mesh Transvaginal mesh- PROLIFT®-system - Pelvic Organ Prolapse | Phase 2 / Phase 3 | Completed | Karolinska Institutet | 250 | 2006-08-01 | 2007-11-14 |
| Mesh Repair of Anterior Vaginal Wall Prolapse Low-weight prolypropylene mesh - Anterior Vaginal Wall Prolapse | Phase 3 | Completed | Tampere University | 202 | 2003-04-01 | 2007-01-11 |
| Pexy Versus Non-pexy for Full Thickness Rectal Prolapse sacral rectopexy with sutures or meshes, full rectal mobilization from the sacrum without sacral rectopexy - Rectal Prolapse | Phase 3 | Completed | Societa Italiana di Chirurgia ColoRettale | 180 | 2003-01-01 | 2009-12-02 |
| Colpopexy and Urinary Reduction Efforts (CARE) Protocol Burch urethropexy at time of sacrocolpopexy - Urinary Incontinence, Stress, Uterine Prolapse | Phase 3 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 322 | 2002-04-01 | 2011-01-11 |
| Promoting Effective Recovery From Labor Urinary Incontinence (PERL) Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing - Urinary Incontinence, Pelvic Organ Prolapse | Phase 3 | Completed | University of Michigan | 140 | 1996-07-01 | 2007-07-31 |
Pelvic Organ Prolapse (12) · Urinary Incontinence (4) · Urinary Incontinence, Stress (3) · Atrophic Vaginitis (1) · Cystocele (1) · Genital Diseases, Female (1) · Lower Urinary Tract Symptoms (1) · Orgasm (1) · Pelvic Floor Disorders (1) · Postoperative Nausea and Vomiting (1) · Rectal Prolapse (1) · Rectocele (1) · Recurrence (1) · Surgical Wound Infection (1) · Urinary Retention (1)
Pathological Conditions, Anatomical (14) · Pathological Conditions, Signs and Symptoms (14) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Urogenital Diseases (8) · Male Urogenital Diseases (7) · Signs and Symptoms (7) · Urologic Diseases (7) · Urination Disorders (6) · Urological Manifestations (6) · Lower Urinary Tract Symptoms (5) · Genital Diseases (3) · Pathologic Processes (3) · Digestive System Diseases (2)
Data Collection (1) · Dexamethasone (1) · Estrogens, Conjugated (USP) (1) · Gels (1) · Lidocaine (1) · Sutures (1) · Tamsulosin (1) · Videotape Recording (1) · alfacalcidol (1)
TriHealth Inc. (2) · University Of Perugia (2) · Ain Shams Maternity Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Karolinska Institutet (1) · Societa Italiana di Chirurgia ColoRettale (1) · Tampere University (1) · Universitas Padjadjaran (1) · University Hospitals Cleveland Medical Center (1) · University of Michigan (1) · University of New Mexico (1) · University of South Florida (1)
United States (8) · Finland (2) · Italy (2) · Denmark (1) · Egypt (1) · Indonesia (1) · Norway (1) · Sweden (1)
Ahmed M Abbas, MD (1) · Araba A Jackson, MD (1) · Carolyn M Sampselle, PhD,RNC,FAAN (1) · Christine M Vaccaro, DO (1) · Daniel Altman, MD, PhD (1) · Graham Chapman (1) · Ihab FS Eldin Allam, MD (1) · Karen Taylor, BA (1) · Kari Nieminen (1) · Linda Brubaker, MD (1) · Massimo Porena, MD Prof in Chief (1) · RM Sonny Sasotya, Ph.D. (1) · Rachel N Pauls, MD (1)
PMID 12790869, PMID 16282227, PMID 16611949, PMID 16897749, PMID 17336819, PMID 18060963, PMID 18060965, PMID 18074068, PMID 18185903, PMID 18455536, PMID 18591307, PMID 18656053, PMID 18716704, PMID 18722933, PMID 18845288, PMID 18976976, PMID 19104367, PMID 19104368, PMID 19701041, PMID 21344495, PMID 22517125, PMID 26032041, PMID 31039170, PMID 32769645, PMID 33894146, PMID 33935807, PMID 34973179, PMID 37431855, PMID 37888839
R01NR004007 (1), U10HD041248 (1), U10HD041250 (1), U10HD041261 (1), U10HD041263 (1), U10HD041267 (1), U10HD041268 (1), U10HD041269 (1)