4 completed, 4 not yet recruiting, 2 unknown, 1 active not recruiting. 10 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 4, Not yet recruiting 4, Enrolling by invitation 1, Unknown 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Pre-Exposure Prophylaxis (PrEP): new trials by email Literature Review of Pre-Exposure Prophylaxis (PrEP) trials Research Report on Pre-Exposure Prophylaxis (PrEP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Peer-led Community-based PrEP Delivery Among Youth in Brazil COMPrEP - Pre-Exposure Prophylaxis (PrEP), HIV | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 1400 | 2026-12-01 | 2026-10-13 |
| Community-based Outreach and Navigation for Nurse-led Engagement in HIV Care and Treatment CONNECT (status-neutral, nurse-led on-site HIV service delivery), Standard of Care (referral-based outreach) - HIV Infections, HIV Prevention | Not applicable | Not yet recruiting | Donaldson Conserve | 360 | 2026-11-01 | 2026-10-13 |
| Nurse-Led PrEP Initiation Among Incarcerated Individuals Nurse-Led Intervention, Patient Navigation Intervention, Standard-of-care (SoC) - HIV Prevention Program, Pre-Exposure Prophylaxis (PrEP) | Not applicable | Not yet recruiting | Rhode Island Hospital | 90 | 2026-09-01 | 2026-08-24 |
| A Self-administered PrEP Decisional Aid for Dissemination With HIV Self-test Kits (DASH) PrEP Decisional Aid for dissemination with Self-administered HIV test kits (DASH) - Pre-Exposure Prophylaxis (PrEP), HIV Prevention | Not applicable | Enrolling by invitation | University of Michigan | 170 | 2026-04-17 | 2026-06-03 |
| Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling Counseling, List of resources - Pre-Exposure Prophylaxis (PrEP), Counseling | Not applicable | Not yet recruiting | Unity Health Toronto | 200 | 2025-01-01 | 2024-11-29 |
| eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum eSTEP, Usual Care - Pre-Exposure Prophylaxis (PrEP) | Not applicable | Completed | San Diego State University | 113 | 2024-04-03 | 2026-06-23 |
| Tshireletso: Safety, Efficacy and Feasibility of Cabotegravir-LA PrEP in a Breastfeeding Population in Botswana Cabotegravir Injection [Apretude] - Pre-Exposure Prophylaxis (PrEP), Breast Feeding | Phase 4 | Active not recruiting | Beth Israel Deaconess Medical Center | 500 | 2023-11-30 | 2026-07-30 |
| PrEPared-RN, CAN Nurse-Led Management of High-risk Patients for Pre-Exposure Prophylaxis (PrEP) Truvada - Hiv Prevention, Pre-Exposure Prophylaxis (PrEP) | Unknown | CAN Community Health | 210 | 2023-04-16 | 2023-09-11 | |
| Pre-exposure Prophylaxis (PrEP) Rapid Access PrEP Rapid Access, HIV self-testing, Dried blood spot testing - Drug Use, Pre-exposure Prophylaxis (PrEP) | Not applicable | Completed | Boston Medical Center | 40 | 2023-04-12 | 2024-07-16 |
| SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs SIRI Checklist, Enhanced Peer Recovery Coach, SIRI Checklist + Enhanced Peer Recovery Coach - HIV Infections, Opioid-Related Disorders | Not applicable | Completed | University of Alabama at Birmingham | 60 | 2022-10-11 | 2026-08-19 |
| A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW PrEP-3D package, Standard of Care - HIV Prevention, Pre-exposure Prophylaxis (PrEP) | Not applicable | Unknown | Public Health Foundation Enterprises, Inc. | 150 | 2022-04-08 | 2022-09-21 |
| Impact of Nursing Involvement on Implementation of HIV Prevention Services PrEP-RN - Pre-Exposure Prophylaxis (PrEP) | Not applicable | Completed | Johns Hopkins University | 440 | 2021-04-01 | 2025-09-19 |
HIV Infections (2) · Opioid-Related Disorders (2) · Bisexuality (1) · Breast Feeding (1) · Coitus (1) · Homosexuality (1) · Medication Adherence (1) · Risk Reduction Behavior (1) · Substance-Related Disorders (1)
Behavior (3) · Blood-Borne Infections (2) · Chemically-Induced Disorders (2) · Communicable Diseases (2) · Genital Diseases (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2) · Infections (2) · Lentivirus Infections (2) · Mental Disorders (2) · Narcotic-Related Disorders (2) · RNA Virus Infections (2) · Retroviridae Infections (2) · Sexually Transmitted Diseases (2) · Sexually Transmitted Diseases, Viral (2)
Standard of Care (3) · Counseling (1) · Dried Blood Spot Testing (1) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · cabotegravir (1) · emtricitabine tenofovir alafenamide (1)
University of Alabama at Birmingham (2) · Beth Israel Deaconess Medical Center (1) · Boston Medical Center (1) · CAN Community Health (1) · Donaldson Conserve (1) · Johns Hopkins University (1) · Public Health Foundation Enterprises, Inc. (1) · Rhode Island Hospital (1) · San Diego State University (1) · Unity Health Toronto (1) · University of Michigan (1)
United States (9) · Botswana (1) · Brazil (1) · Canada (1)
Darrell H.S. Tan, MD, FRCPC, PHD (1) · Donaldson F Conserve, PhD, MS (1) · Jenell Coleman, MD, MPH (1) · K Rivet Amico, PhD (1) · Katia J Bruxvoort, PhD (1) · Keith J Horvath, PhD (1) · Rebecca Zash, MD (1) · Sabrina Assoumou, MD MPH (1) · Susan Buchbinder, MD (1) · Susan J Little, MD (1) · Susan Ramsey, PhD (1)
R01HD108047 (1), R01MH135769 (1), R01NR021169 (1), R34MH135799 (1)