11 completed, 9 unknown, 5 recruiting, 3 terminated. 21 Not applicable, 3 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 6, Unknown 6, Recruiting 4, Terminated 2, Enrolling by invitation 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Pilonidal Disease: new trials by email Literature Review of Pilonidal Disease trials Research Report on Pilonidal Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intraoperative Wound Irrigation for Pilonidal Disease Hypochlorous Acid - Pilonidal Disease | Not applicable | Recruiting | Stanford University | 72 | 2026-03-01 | 2026-05-26 |
| Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease Irrisept (0.05% chlorhexidine gluconate), Normal Saline - Pilonidal Disease | Not applicable | Recruiting | Yosef Nasseri, MD | 60 | 2026-02-17 | 2026-03-27 |
| Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker Skin Color Laser hair depilation, Standard of Care (SOC) - Pilonidal Disease | Not applicable | Recruiting | Nemours Children's Clinic | 36 | 2025-10-01 | 2026-10-14 |
| Topical Anti-Androgens in Pilonidal Sinus Disease 1% Clascoterone, Vehicle Cream - Pilonidal Disease, Pilonidal Disease of Natal Cleft | Phase 2 | Recruiting | University of Pennsylvania | 75 | 2025-01-10 | 2026-02-27 |
| Pain Control for Laser Epilation in Pilonidal Disease Topical lidocaine, Sham cream - Pilonidal Disease | Phase 4 | Completed | David Mooney | 20 | 2024-11-01 | 2025-06-18 |
| Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone) Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure - Pilonidal Sinus, Pilonidal Disease | Not applicable | Not yet recruiting | dr. IJM Han-Geurts | 482 | 2024-08-28 | 2024-08-29 |
| The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell - Pilonidal Sinus, Pilonidal Disease | Not applicable | Unknown | Mustafa Azizoğlu | 120 | 2024-05-11 | 2024-05-14 |
| A Trial in Mini-invasive Pilonidal Sinus Disease Surgery surgery + laser, surgery + fibrine glue - Pilonidal Disease | Not applicable | Enrolling by invitation | Helsinki University Central Hospital | 188 | 2023-09-01 | 2025-05-09 |
| Injection of Freshly Collected Autologous Adipose Tissue Additional to Bascom's Cleft Lift Surgery injection of freshly collected adipose cells, Bascoms Cleft lift procedure - Pilonidal Disease | Not applicable | Unknown | University of Aarhus | 140 | 2023-01-04 | 2023-04-26 |
| Comparison of Laser Destruction of Pilonidal Sinus Disease (SILAC) and Bascom II Procedure. Bascom II procedure, SiLaC - Pilonidal Disease | Not applicable | Unknown | Russian Society of Colorectal Surgeons | 164 | 2022-12-08 | 2023-02-08 |
| Comparing Operative vs Non Operative Treatment for Pilonidal Disease Regular Epilation Regimen, Surgical excision - Pilonidal Disease | Not applicable | Recruiting | Stanford University | 400 | 2022-07-19 | 2024-11-22 |
| Unroofing Curettage for Pilonidal Disease unroofing curettage - Pilonidal Disease, Recurrence | Completed | Ankara Diskapi Training and Research Hospital | 203 | 2022-04-27 | 2022-10-27 | |
| Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery Platelet rich plasma - Pilonidal Disease, Pilonidal Sinus | Not applicable | Completed | İsmail Oskay Kaya | 140 | 2021-11-01 | 2024-01-16 |
| Clinical Trial to Test the Phenolization in Sacrococcygeal Pilonidal Disease phenolization, Conventional surgery - Sacrococcygeal Fistula, Pilonidal Sinus | Phase 4 | Completed | HJ23 | 122 | 2021-01-01 | 2022-06-07 |
| Surgical Approach for Pilonidal Disease Un-roofing curettage method, Modified Limberg Flap Group - Pilonidal Disease | Completed | Konya Meram State Hospital | 278 | 2020-04-02 | 2022-10-27 | |
| The Management of Pilonidal Wounds With ACell MicroMatrix® and Cytal® Wound Matrix: A Case Series Wound Sheet Matrix 2-Layer and Powder Urinary Bladder Matrix - Pilonidal Disease | Terminated | Integra LifeSciences Corporation | 2 | 2019-03-26 | 2021-04-20 | |
| Laser Hair Removal for Treatment of Pilonidal Disease Laser hair removal - Pilonidal Disease | Not applicable | Completed | University of Wisconsin, Madison | 22 | 2019-02-18 | 2021-12-17 |
| Randomized Trial Comparing Prevena and ActiV.A.C. System to Convetional Care After Bascom's Cleft Lift Surgery Prevena™ og ACTIV.A.C™ Therapy System. - Pilonidal Disease | Not applicable | Terminated | University of Aarhus | 106 | 2019-01-14 | 2022-05-19 |
| MIPE for Pilonidal Disease minimally invasive pilonidal excision - Pilonidal Disease, Pilonidal Cyst/Fistula | Unknown | Northwell Health | 151 | 2019-01-01 | 2022-11-17 | |
| Excision and Reconstruction of the Natal Cleft With a Parasacral Perforator Flap Versus Open Excision With Secondary Healing, in the Management of Sacrococcygeal Pilonidal Disease. parasacral flap reconstruction, open excision - Pilonidal Disease | Not applicable | Terminated | University Hospital, Toulouse | 21 | 2018-06-01 | 2024-01-03 |
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Pilonidal Sinus (11) · Recurrence (3) · Pain (1)
Cysts (11) · Neoplasms (11) · Pathological Conditions, Signs and Symptoms (4) · Disease Attributes (3) · Pathologic Processes (3) · Neurologic Manifestations (1) · Signs and Symptoms (1)
Laser Therapy (2) · Negative-Pressure Wound Therapy (2) · Clascoterone (1) · Conversion to Open Surgery (1) · Curettage (1) · Hypochlorous Acid (1) · Lidocaine (1) · Saline Solution (1) · Standard of Care (1) · Surgical Procedures, Operative (1) · Therapeutic Irrigation (1)
Konya Meram State Hospital (2) · Stanford University (2) · University of Aarhus (2) · Ankara Diskapi Training and Research Hospital (1) · Cihangir Akyol (1) · David Mooney (1) · HJ23 (1) · Helsinki University Central Hospital (1) · Integra LifeSciences Corporation (1) · Istanbul Medipol University Hospital (1) · London North West Healthcare NHS Trust (1) · Mansoura University (1) · Mustafa Azizoğlu (1) · Nationwide Children's Hospital (1) · Nemours Children's Clinic (1)
United States (14) · Turkey (Türkiye) (7) · Denmark (2) · Egypt (1) · Finland (1) · France (1) · Ireland (1) · Russia (1) · Spain (1)
Bill Chiu, MD (2) · Abdulraouf Lamoshi, MD (1) · Ashley P Stoeckel, MD (1) · Can Y Boztug, MD (1) · Charlotte Kvasnovsky, MD, PhD, MPH (1) · Cihangir Akyol, MD (1) · Deborah S Keller, MS MD (1) · Engin Olcucuoglu, MD (1) · Eric M Haas, MD (1) · Haane Massarotti, MD (1) · Inna Tulina, PhD (1) · Katherine J Deans, MD, MHSc (1) · Kemal Arslan, MD (1) · Lalin Navaratne, MBBS MRCS (1)
PMID 13900261, PMID 14605577, PMID 18937009, PMID 19198934, PMID 26531235, PMID 28042633, PMID 28352930, PMID 30382903, PMID 33856512, PMID 34670534, PMID 34840296, PMID 34993686, PMID 36304191, PMID 37938854, PMID 42128975, PMID 42288936, PMID 7016481, PMID 7956585
U54GM104941 (1)