11 completed, 3 recruiting, 2 unknown, 1 not yet recruiting. 8 Not applicable, 4 Phase 2, 3 Phase 4, 2 Phase 3, 1 Early Phase 1.
Follow Hypochlorous Acid: new trials by email Literature Review of Hypochlorous Acid trials Research Report on Hypochlorous Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Standard of Care Drugs With or Without Ivermectin for Daraxonrasib-Induced Skin Toxicity in People With Pancreatic Cancer Minocycline, Hypochlorous Acid, Hydrocortison cream - Pancreatic Cancer, Skin Toxicities | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 122 | 2026-10-16 | 2026-10-26 |
| Sequential Treatment Approaches for Treatment-Resistant Schizophrenia [Phase 1] Clozapine, [Phase 1] Aripiprazole, [Phase 1] Amisulpride - Treatment-resistant Schizophrenia | Phase 3 | Recruiting | Shanghai Mental Health Center | 300 | 2026-09-01 | 2026-11-05 |
| Prevention of Vascular Graft Infection With Hypochlorous Acid Hypochlorous acid - Vascular Prosthetic Graft Infection | Not applicable | Not yet recruiting | Hamilton Health Sciences Corporation | 500 | 2026-08-03 | 2026-07-01 |
| Intraoperative Wound Irrigation for Pilonidal Disease Hypochlorous Acid - Pilonidal Disease | Not applicable | Recruiting | Stanford University | 72 | 2026-03-01 | 2026-05-26 |
| Efficacy of Hypochlorous Acid as a Postoperative Wound Antiseptic Hypochlorous acid - Wound Healing | Not applicable | Completed | Ataturk University | 24 | 2023-05-02 | 2025-01-06 |
| 0.01% Hypochlorous Acid in the Treatment of Blepharitis 0.01% hypochlorous acid, Placebo - Blepharitis | Not applicable | Unknown | Eye & ENT Hospital of Fudan University | 100 | 2022-07-01 | 2022-11-08 |
| Comparison of the Clinical and Microbiological Effects of CHX and HOCl Containing Mouthwashes Hypochlorous acid 0.02% mouthwash, Chlorhexidine gluconate 0.2% mouthwash - Dental Plaque | Not applicable | Completed | Baskent University | 30 | 2022-03-28 | 2026-11-04 |
| Comparison of Chlorhexidine and Hypochlorous Acid Mouthwash After Impacted Third Molar Surgery Hypochlorous Acid, Chlorhexidine Gluconate Mouthwash - Impacted Mandibular Third Molar | Not applicable | Completed | Yuzuncu Yil University | 42 | 2021-12-01 | 2026-03-12 |
| The Efficacy of Oral Antiseptics Against COVID-19 Hypochlorous Acid 0.02% Soln,Top (Crystaline) (HClO) - COVID-19 | Phase 4 | Completed | Ataturk University | 75 | 2021-09-01 | 2022-02-11 |
| Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine Betadine, AvenovaTM - Eye Infections, Bacterial | Phase 4 | Terminated | University of Miami | 20 | 2021-08-06 | 2026-11-05 |
| Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used hypochlorous acid - Newborn; Infection, Disinfection | Not applicable | Completed | Hisar Intercontinental Hospital | 60 | 2021-05-05 | 2022-01-03 |
| MOUTHRİNSES AND PALATAL DONOR SİTE HEALİNG AFTER FREE GİNGİVAL GRAFT Hypochlorous Acid, Hyaluronic Acid (HA), Chlorhexidine gluconate 0.2% - Palatal Donor Site Wound Healing, Periodontal Plastic Surgery | Not applicable | Completed | Yuzuncu Yil University | 54 | 2020-06-20 | 2026-07-08 |
| Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study) Povidone Iodine, Hypochlorous Acid - Age-related Macular Degeneration, Diabetic Retinopathy | Phase 4 | Completed | California Retina Consultants | 50 | 2019-07-16 | 2020-03-10 |
| AvenovaTM as a Sterile Skin Preparation Agent Avenova, Povidone-iodine 5% solution, 4% chlorhexidine - Cleaning Product Causing Toxic Effect | Early Phase 1 | Completed | University of Miami | 21 | 2018-12-01 | 2020-02-05 |
| HYPOCHLOROUS ACID SUBSTANTIVITY AS ANTIPLAQUE AGENT (HOCl-SAP) Hypochlorous Acid, Chlorhexidine, Placebo - Hypochlorous Acid, Mouthwashes | Phase 2 | Completed | Universidad El Bosque, Bogotá | 75 | 2015-01-15 | 2017-10-26 |
| Chlorhexidine Against Sodium Hypochlorite as Skin Antiseptics Bacterial culture of the prepared skin's areas, Preparing skin's areas to be tested, Antiseptic substantivity - Infectious Diseases | Phase 3 | Completed | Universidad de Guanajuato | 30 | 2011-04-01 | 2013-06-24 |
| Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies Thiotepa, Clofarabine, Busulfan - Stem Cell Transplantation, Leukemia | Phase 2 | Completed | M.D. Anderson Cancer Center | 60 | 2009-03-02 | 2020-04-07 |
| Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone Hypochlorous acid, Iodopovidone - Surgical Site Infection | Phase 2 | Unknown | Universidad Tecnológica de Pereira | 432 | 2008-07-01 | 2008-10-21 |
Blepharitis (1) · COVID-19 (1) · Communicable Diseases (1) · Cross Infection (1) · Dental Plaque (1) · Diabetic Retinopathy (1) · Eye Infections, Bacterial (1) · Gingival Overgrowth (1) · Infections (1) · Leukemia (1) · Lymphoma (1) · Macular Degeneration (1) · Meibomian Gland Dysfunction (1) · Neoplasms (1) · Pancreatic Neoplasms (1)
Ataturk University (2) · University of Miami (2) · Yuzuncu Yil University (2) · Baskent University (1) · California Retina Consultants (1) · Eye & ENT Hospital of Fudan University (1) · Hamilton Health Sciences Corporation (1) · Hisar Intercontinental Hospital (1) · M.D. Anderson Cancer Center (1) · Memorial Sloan Kettering Cancer Center (1) · Shanghai Mental Health Center (1) · Stanford University (1) · Universidad El Bosque, Bogotá (1) · Universidad Tecnológica de Pereira (1) · Universidad de Guanajuato (1)
Turkey (Türkiye) (6) · United States (6) · China (2) · Colombia (2) · Canada (1) · Mexico (1)
Alejandro E Macias, M. D. (1) · Allison Gordon, MD (1) · Alparslan Dilsiz, Prof. (1) · Basri Cakiroglu (1) · Bill Chiu, MD (1) · DengTang Liu (1) · Gloria Ines Lafaurie, MS (1) · Jiaxu Hong (1) · Jorge Fortun, MD (1) · Juliana Buitrago, MD.,MSc (1) · Kris M. Mahadeo, MD (1) · Mehtap Bilgin Cetin, Associate Professor (1) · Robert Avery, MD (1)
PMID 17492050, PMID 26647939, PMID 27447617, PMID 35904769, PMID 8682921