5 completed, 2 recruiting, 1 not yet recruiting, 1 unknown. 4 Not applicable, 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Not yet recruiting 1, Unknown 1 |
Follow Odontogenic Tumors: new trials by email Literature Review of Odontogenic Tumors trials Research Report on Odontogenic Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant Therapy With Conservative Surgery vs. Up-front Conservative Surgery for BRAF V600E-Mutated Ameloblastoma Dabrafenib and trametinib (combination) - Ameloblastoma | Phase 2 / Phase 3 | Not yet recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 46 | 2025-03-01 | 2025-02-11 |
| RFA and Bite Force in COD Teeth Resonance Frequency Analysis (RFA), Bite Force Sensor - Tooth Ankylosis, Cemento-Osseous Dysplasia | Not applicable | Completed | Eskisehir Osmangazi University | 17 | 2025-01-02 | 2025-09-22 |
| Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin Virtual lesion segmentation for mandibular ameloblastoma - Ameloblastoma | Not applicable | Recruiting | Alexandria University | 10 | 2025-01-01 | 2025-12-29 |
| Exploration of Fenestration Decompression Combined With Dalafenib in the Treatment of BRAF Mutant Ameloblastoma Dabrafenib - Ameloblastoma | Phase 3 | Unknown | Shandong University | 10 | 2024-03-01 | 2024-02-20 |
| Effect of Tetracycline Socked Pack on Acceleration of Healing During Marsupialization Tetracyclin - Ameloblastoma | Not applicable | Completed | Minia University | 14 | 2024-02-10 | 2025-01-06 |
| Clinical Study of Neoadjuvant Targeted Therapy for Ameloblastoma Dabrafenib, Trametinib - Ameloblastoma, BRAF V600E Mutation Positive | Phase 2 | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 12 | 2023-01-01 | 2024-10-22 |
| Evaluation of the Expression and Prognostic Role of Tumor Stem Cell Marker SOX2 in Odontogenic Cysts and Tumors Odontogenic Cysts, Odontogenic Tumors | Completed | Mansoura University | 45 | 2022-04-01 | 2025-02-26 | |
| Computer Guided Buccal Cortical Plate Separation for Removal of Calcified Benign Odontogenic Tumors Affecting Mandibular Angle Region Computer guided buccal cortical plate separation - Odontogenic Tumors, Odontoma | Not applicable | Completed | Cairo University | 10 | 2018-04-01 | 2022-04-15 |
| Dabrafenib and Trametinib in Treating Patients With BRAF Mutated Ameloblastoma Dabrafenib, Trametinib - Ameloblastoma, BRAF Gene Mutation | Phase 2 | Completed | Stanford University | 1 | 2017-07-17 | 2024-01-30 |
Ameloblastoma (7) · Adamantinoma (1) · Cementoma (1) · Dentigerous Cyst (1) · Disease (1) · Jaw Diseases (1) · Odontogenic Cysts (1) · Odontoma (1) · Tooth Ankylosis (1)
Neoplasms (9) · Neoplasms by Histologic Type (9) · Musculoskeletal Diseases (3) · Stomatognathic Diseases (2) · Bone Cysts (1) · Bone Diseases (1) · Bone Neoplasms (1) · Cysts (1) · Jaw Cysts (1) · Jaw Diseases (1) · Neoplasms by Site (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Tooth Diseases (1)
dabrafenib (4) · trametinib (3) · Tetracycline (1)
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (2) · Alexandria University (1) · Cairo University (1) · Eskisehir Osmangazi University (1) · Mansoura University (1) · Minia University (1) · Shandong University (1) · Stanford University (1)
Egypt (4) · China (1) · Turkey (Türkiye) (1) · United States (1)
Alexander Colevas (1) · Qing Li (1)
PMID 14579951, PMID 2094658, PMID 36136180, PMID 37966914, PMID 39274556, PMID 41176605