80 completed, 25 terminated, 5 withdrawn, 3 active not recruiting. 59 Phase 1, 50 Phase 2, 14 Not applicable, 2 Early Phase 1, 1 Phase 3.
Follow Nodal Marginal Zone B-cell Lymphoma: new trials by email Literature Review of Nodal Marginal Zone B-cell Lymphoma trials Research Report on Nodal Marginal Zone B-cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma rituximab, lenalidomide, romidepsin - B-cell Adult Acute Lymphoblastic Leukemia, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Phase 1 / Phase 2 | Withdrawn | Mayo Clinic | 2016-10-01 | 2016-08-11 | |
| Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma carmustine, cytarabine, melphalan - Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma | Not applicable | Withdrawn | Fred Hutchinson Cancer Center | 2015-02-01 | 2015-05-07 | |
| CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma 6,8-bis(benzylthio)octanoic acid, bendamustine hydrochloride, rituximab - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia | Phase 1 | Terminated | Wake Forest University Health Sciences | 1 | 2014-12-01 | 2018-07-02 |
| A Phase I/II Study of Intratumoral Injection of SD-101 Ipilimumab, SD-101, Radiation therapy - Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma | Phase 1 / Phase 2 | Completed | Robert Lowsky | 9 | 2014-09-01 | 2019-11-27 |
| Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas lenalidomide, etoposide, prednisone - Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | University of Chicago | 55 | 2014-07-29 | 2026-03-11 |
| Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma PI3K inhibitor BKM120, rituximab, Pharmacodynamics - Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma | Phase 1 | Completed | Kami Maddocks, MD | 18 | 2014-07-21 | 2022-06-30 |
| Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma BTK inhibitor PCI-32765, rituximab, bendamustine hydrochloride - Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma | Phase 1 | Active not recruiting | Kami Maddocks, MD | 48 | 2014-03-26 | 2026-07-22 |
| Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant busulfan, etoposide, cyclophosphamide - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Early Phase 1 | Completed | Case Comprehensive Cancer Center | 33 | 2014-03-01 | 2015-08-13 |
| Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies cyclophosphamide, fludarabine phosphate, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 2 | Withdrawn | University of Medicine and Dentistry of New Jersey | 2014-01-01 | 2016-07-14 | |
| MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma anti-endosialin/TEM1 monoclonal antibody MORAb-004, pharmacological study, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 | Completed | Morphotek | 27 | 2013-11-01 | 2016-01-08 |
| Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells, autologous hematopoietic stem cell transplantation, laboratory biomarker analysis - Adult Grade III Lymphomatoid Granulomatosis, Cutaneous B-cell Non-Hodgkin Lymphoma | Phase 1 | Active not recruiting | City of Hope Medical Center | 30 | 2013-10-08 | 2026-06-25 |
| Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies vorinostat, tacrolimus, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | National Cancer Institute (NCI) | 12 | 2013-06-01 | 2018-07-24 |
| Alisertib With and Without Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma alisertib, rituximab, laboratory biomarker analysis - Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue, Nodal Marginal Zone B-cell Lymphoma | Phase 2 | Terminated | Ohio State University Comprehensive Cancer Center | 14 | 2013-05-21 | 2018-06-06 |
| Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies therapeutic allogeneic lymphocytes, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 2 | Completed | University of Chicago | 77 | 2013-04-04 | 2019-08-07 |
| Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas brentuximab vedotin, rituximab, laboratory biomarker analysis - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 / Phase 2 | Terminated | Northwestern University | 20 | 2013-03-05 | 2021-09-01 |
| Ipilimumab and Local Radiation for Selected Solid Tumors Ipilimumab, Radiation therapy - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 | Terminated | Stanford University | 3 | 2013-02-01 | 2024-01-24 |
| Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant tetanus-CMV fusion peptide vaccine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | City of Hope Medical Center | 36 | 2012-10-29 | 2024-04-02 |
| Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant management of therapy complications, musculoskeletal complications management/prevention - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Not applicable | Withdrawn | Roswell Park Cancer Institute | 2012-05-01 | 2012-07-09 | |
| Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant lenalidomide, rituximab, pharmacological study - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 3 | 2012-05-01 | 2017-07-27 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
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Lymphoma, B-Cell, Marginal Zone (113) · Lymphoma, Follicular (111) · Leukemia, Lymphocytic, Chronic, B-Cell (102) · Lymphoma, Mantle-Cell (101) · Lymphoma, Large B-Cell, Diffuse (96) · Lymphoma, Non-Hodgkin (93) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (91) · Waldenstrom Macroglobulinemia (89) · Burkitt Lymphoma (88) · Lymphoma, Large-Cell, Immunoblastic (85) · Hodgkin Disease (68) · Mycosis Fungoides (68) · Sezary Syndrome (68) · Lymphoma, T-Cell, Cutaneous (67) · Lymphoma, Large-Cell, Anaplastic (58)
Hemic and Lymphatic Diseases (113) · Immune System Diseases (113) · Immunoproliferative Disorders (113) · Lymphatic Diseases (113) · Lymphoproliferative Disorders (113) · Neoplasms by Histologic Type (113) · Hematologic Diseases (112) · Lymphoma (112) · Neoplasms (112) · Lymphoma, B-Cell (111) · Leukemia, Lymphoid (106) · Leukemia (105) · Disease Attributes (103) · Pathologic Processes (103) · Pathological Conditions, Signs and Symptoms (103)
Rituximab (26) · Peripheral Blood Stem Cell Transplantation (21) · fludarabine phosphate (21) · Whole-Body Irradiation (18) · Mycophenolic Acid (17) · Cyclophosphamide (14) · Cyclosporine (14) · Flow Cytometry (10) · Etoposide (8) · Tacrolimus (8) · Busulfan (7) · Bortezomib (6) · Lenalidomide (6) · Filgrastim (5) · Granulocyte Colony-Stimulating Factor (5)
National Cancer Institute (NCI) (43) · Fred Hutchinson Cancer Center (26) · Case Comprehensive Cancer Center (6) · City of Hope Medical Center (6) · Mayo Clinic (5) · Roswell Park Cancer Institute (5) · Wake Forest University Health Sciences (3) · Kami Maddocks, MD (2) · Robert Lowsky (2) · University of Chicago (2) · University of Washington (2) · Amir Mortazavi (1) · Barbara Ann Karmanos Cancer Institute (1) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1) · Martin, Paul (1)
United States (110) · Italy (7) · Germany (4) · Canada (2)
Ajay Gopal (7) · David Maloney (6) · Brenda Sandmaier (4) · Paul Martin (3) · Ryotaro Nakamura (3) · Anas Younes (2) · Ann Woolfrey (2) · Brenda Cooper (2) · George Chen (2) · John Byrd (2) · Kami Maddocks, MD (2) · Patricia LoRusso (2) · Philip McCarthy (2) · Ramesh Ramanathan (2) · Sonali Smith (2)
PMID 32499241, PMID 18698002, PMID 19900571, PMID 20837940, PMID 21508413, PMID 22259028, PMID 22308288, PMID 23256542, PMID 24241210, PMID 24474568, PMID 24530971, PMID 25355819, PMID 26213141, PMID 26764356, PMID 26853648, PMID 26943915, PMID 27118452, PMID 28270022, PMID 28817727, PMID 29292843, PMID 29572391, PMID 30454872, PMID 30562587, PMID 31388792, PMID 31481800, PMID 32628342, PMID 33420905, PMID 33492438, PMID 34515338, PMID 34780125, PMID 36282798, PMID 40720747
P30CA015704 (14), U01CA076576 (7), P01CA018029 (5), U01CA062487 (5), U01CA062491 (5), U01CA062502 (5), U01CA099168 (5), P30CA015083 (4), N01CM17003 (3), N01CM62202 (3), P01CA044991 (3), P01CA078902 (3), U01CA062505 (3), U01CA069912 (3), P30CA014599 (2)