376 recruiting. 376 Phase 1, 170 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 376 | Recruiting 376 |
| Phase 2 | 170 | Recruiting 170 |
Follow Neuroectodermal Tumors: new trials by email Literature Review of Neuroectodermal Tumors trials Research Report on Neuroectodermal Tumors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography - Recurrent Ganglioneuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2027-06-25 | 2026-11-03 |
| Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis Nivolumab and Relatlimab, Melphalan - Metastatic Melanoma, Liver Metastases | Phase 1 / Phase 2 | Recruiting | University of Wisconsin, Madison | 15 | 2026-11-01 | 2026-10-30 |
| TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma 5-ALA, Porphyrin Metabolite Activation (PoMA) with LIDU ultrasound - Glioblastom WHO Grade 4, GBM | Phase 1 | Recruiting | Alpheus Medical, Inc. | 30 | 2026-10-29 | 2026-10-09 |
| Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease Autologous B7-H3 CAR T, Cyclophosphamide, Fludarabine - Recurrent Small Cell Lung Cancer, Extensive-Stage Small Cell Lung Cancer | Phase 1 | Recruiting | National Cancer Institute (NCI) | 40 | 2026-10-16 | 2026-10-29 |
| Rituximab for Treatment of Checkpoint Inhibitor Induced Immune-related Adverse Events Rituximab (RTX) - Immune-Related Adverse Events | Phase 1 | Recruiting | Inge Marie Svane | 25 | 2026-10-15 | 2026-10-20 |
| A Study of BL-M08D in Patients With Locally Advanced or Metastatic Melanoma and Other Solid Tumors BL-M08D1 - Melanoma, Solid Tumors | Phase 1 / Phase 2 | Recruiting | Sichuan Baili Pharmaceutical Co., Ltd. | 30 | 2026-10-13 | 2026-10-29 |
| Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases DNX-2401 - Melanoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 50 | 2026-09-25 | 2026-11-02 |
| Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma Bmab1700, Opdivo - Melanoma | Phase 1 | Recruiting | Biocon Biologics UK PLC | 120 | 2026-09-09 | 2026-09-25 |
| A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors NEO100 - Pediatric Tumor of CNS, Pediatric Tumor of Brain | Phase 1 | Recruiting | Neonc Technologies, Inc. | 12 | 2026-09-08 | 2026-09-15 |
| B7-H3.CD28Z.CART in CNS Neoplasms B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide - Central Nervous System Neoplasms, Brain Tumor | Phase 1 | Recruiting | Robbie Majzner | 70 | 2026-09-01 | 2026-09-03 |
| NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab - Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma, High Grade Gliomas | Phase 1 | Recruiting | Children's National Research Institute | 30 | 2026-09-01 | 2026-09-09 |
| Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLC Bexmarilimab 1mg/kg and nivolumab 1mg/kg, Bexmarilimab 3mg/kg and nivolumab 1mg/kg, Recommended Phase II Dose - Melanoma (Skin Cancer), Non Small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | Institute of Cancer Research, United Kingdom | 62 | 2026-08-28 | 2026-09-08 |
| A Study of Armored CAR T Cells in People With Cancer DLL3-SAVVYZ-IL18 CAR T cell - Neuroendocrine Cancer, Small Cell Lung Cancer | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 16 | 2026-08-28 | 2026-10-22 |
| B7-H3.CD28Z.CART in Solid Tumors B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide - Pediatric Solid Tumor, Neuroblastoma | Phase 1 | Recruiting | Robbie Majzner | 40 | 2026-08-24 | 2026-09-03 |
| Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease Liothyronine (L-T3), Bevacizumab, Irinotecan - Medulloblastoma, Medulloblastoma, Childhood | Phase 1 / Phase 2 | Recruiting | Sabine Mueller, MD, PhD | 69 | 2026-08-21 | 2026-09-28 |
| A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma NK Cells - Phase 1, NK Cell | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 36 | 2026-08-21 | 2026-08-25 |
| BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma hEGFRvIII-CD3 (BRiTE) - Newly Diagnosed Glioblastoma, Recurrent Glioblastoma | Phase 1 | Recruiting | Mustafa Khasraw, MBChB, MD, FRCP, FRACP | 18 | 2026-08-17 | 2026-08-18 |
| Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC) 203Pb-RMX-VHPIB injection, SPECT/CT Imaging - Glioblastoma Multiforme (GBM), Pancreatic Ductal Adenocarcinoma (PDAC) | Phase 1 | Recruiting | Radiomedix, Inc. | 20 | 2026-08-15 | 2026-08-07 |
| SL-28 for Advanced Solid Tumours SL-28 - Head & Neck Cancer, Pancreas Carcinoma | Phase 1 / Phase 2 | Recruiting | Second Life Therapeutics | 60 | 2026-08-14 | 2026-09-15 |
| Pharmacokinetic Similarity Study to Compare AVT32-DRL_PB With Keytruda® in Participants With Fully Resected Melanoma AVT32-DRL_PB, Keytruda - Melanoma | Phase 1 | Recruiting | Alvotech Swiss AG | 120 | 2026-08-10 | 2026-08-24 |
Showing 20 of 376. Sign in to see all of them.
Melanoma (135) · Glioblastoma (105) · Glioma (72) · Carcinoma, Non-Small-Cell Lung (51) · Neuroblastoma (37) · Brain Neoplasms (36) · Neoplasm Metastasis (35) · Neoplasms (35) · Colorectal Neoplasms (28) · Ovarian Neoplasms (25) · Squamous Cell Carcinoma of Head and Neck (25) · Astrocytoma (24) · Carcinoma, Renal Cell (23) · Lung Neoplasms (23) · Neuroendocrine Tumors (23)
Neoplasms, Nerve Tissue (374) · Neoplasms by Histologic Type (372) · Neoplasms, Germ Cell and Embryonal (367) · Neoplasms (341) · Neoplasms, Glandular and Epithelial (274) · Neoplasms by Site (229) · Neoplasms, Neuroepithelial (198) · Neuroendocrine Tumors (163) · Skin Diseases (144) · Skin and Connective Tissue Diseases (144) · Nevi and Melanomas (141) · Skin Neoplasms (128) · Glioma (92) · Astrocytoma (83)
pembrolizumab (33) · Temozolomide (31) · Cyclophosphamide (26) · Nivolumab (25) · Magnetic Resonance Spectroscopy (22) · fludarabine (18) · Specimen Handling (16) · Biopsy (11) · Bevacizumab (10) · Ipilimumab (10) · Radiotherapy (10) · Irinotecan (8) · Paclitaxel (7) · fludarabine phosphate (6) · Interleukin-2 (5)
National Cancer Institute (NCI) (15) · M.D. Anderson Cancer Center (14) · Memorial Sloan Kettering Cancer Center (8) · Beijing Biotech (5) · Mayo Clinic (5) · Baylor College of Medicine (4) · Suzhou Zelgen Biopharmaceuticals Co.,Ltd (4) · University of Florida (4) · Cerenome (3) · Children's National Research Institute (3) · City of Hope Medical Center (3) · Darell Bigner (3) · Duke University (3) · Essen Biotech (3) · Hadassah Medical Organization (3)
United States (250) · China (67) · Australia (36) · Spain (20) · United Kingdom (19) · South Korea (15) · Canada (14) · Netherlands (14) · France (13) · Germany (13) · Italy (11) · Japan (11) · Denmark (9) · Taiwan (9) · Belgium (8)
Frank I Lin, M.D. (3) · Jason Wu (3) · Yizhuo Zhang (3) · Andrew J Brenner, PhD (2) · Ashley Plant-Fox, MD (2) · Behnam Badie (2) · Hongwei Zhang, Prof. (2) · Howard Colman, MD, PhD (2) · John Boockvar, MD (2) · Josh Neman, PhD (2) · Juanita Lopez, MD, PhD (2) · Sabine Mueller (2)
PMID 31401903, PMID 12675312, PMID 13680158, PMID 15173079, PMID 16200343, PMID 16344433, PMID 16530701, PMID 16786120, PMID 16899365, PMID 17664336, PMID 17705175, PMID 18509186, PMID 19097774, PMID 19221744, PMID 19223865, PMID 19534336, PMID 19760366, PMID 20167817, PMID 20838435, PMID 21147753, PMID 21150307, PMID 21327941, PMID 22284691, PMID 22665268, PMID 22931705, PMID 23243055, PMID 23844725, PMID 24026531, PMID 24862830, PMID 24947313, PMID 25423330, PMID 25856312, PMID 26311731, PMID 26545842, PMID 27006176, PMID 27230974, PMID 27247755, PMID 27489285, PMID 27782828, PMID 28439777, PMID 28645940, PMID 29123084, PMID 29412784, PMID 29534198, PMID 30093503, PMID 30397180, PMID 31057686, PMID 31231443, PMID 31484667, PMID 31812554
2023 (11), 2025 (6), P30CA033572 (3), P50CA097257 (2), UM1CA186717 (2), UM1CA228823 (2), 2014 (1), 2018 (1), K12CA120780 (1), P30CA016042 (1), P30CA016672 (1), P30CA060553 (1), P30CA093373 (1), P50CA211015 (1), R01CA109767 (1)