Myeloproliferative Neoplasm: Clinical Trials

4 trials for Myeloproliferative Neoplasm, newest first

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2 active not recruiting, 2 completed. 4 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 34Active not recruiting 2, Completed 2

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Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk
Ropeginterferon alfa-2b, Placebo - Primary Myelofibrosis, Myeloproliferative Neoplasm
Phase 3Active not recruitingPharmaEssentia1602025-07-182026-08-13
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Asparaginase, Asparaginase Erwinia chrysanthemi, Cytarabine - Acute Myeloid Leukemia, Down Syndrome
Phase 3Active not recruitingChildren's Oncology Group2802015-12-232026-08-19
Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention
tacrolimus, methotrexate, Mycophenolate mofetil - Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia
Phase 3CompletedCase Comprehensive Cancer Center1012014-07-072023-09-11
Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant
Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Fludarabine Phosphate - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Phase 3CompletedFred Hutchinson Cancer Center1742010-11-012026-04-30

Narrower conditions

Myeloproliferative Disorders (4)  ·  Leukemia, Myeloid, Acute (3)  ·  Myelodysplastic Syndromes (3)  ·  Hodgkin Disease (2)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (2)  ·  Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2)  ·  Multiple Myeloma (2)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (2)  ·  Down Syndrome (1)  ·  Hematologic Neoplasms (1)  ·  Leukemia, Biphenotypic, Acute (1)  ·  Leukemia, Prolymphocytic (1)  ·  Leukemia, Prolymphocytic, T-Cell (1)  ·  Lymphoma, Large B-Cell, Diffuse (1)  ·  Lymphoma, Mantle-Cell (1)

Broader conditions

Bone Marrow Diseases (4)  ·  Hematologic Diseases (4)  ·  Hemic and Lymphatic Diseases (4)  ·  Leukemia (3)  ·  Leukemia, Myeloid (3)  ·  Neoplasms (3)  ·  Neoplasms by Histologic Type (3)  ·  Blood Protein Disorders (2)  ·  Cardiovascular Diseases (2)  ·  Chronic Disease (2)  ·  Disease Attributes (2)  ·  Hemorrhagic Disorders (2)  ·  Hemostatic Disorders (2)  ·  Immune System Diseases (2)  ·  Immunoproliferative Disorders (2)

Interventions

Mycophenolic Acid (2)  ·  Asparaginase (1)  ·  Cyclosporine (1)  ·  Cyclosporins (1)  ·  Cytarabine (1)  ·  Daunorubicin (1)  ·  Etoposide (1)  ·  Leyk (1)  ·  Methotrexate (1)  ·  Mitoxantrone (1)  ·  Peripheral Blood Stem Cell Transplantation (1)  ·  Sirolimus (1)  ·  Tacrolimus (1)  ·  Thioguanine (1)  ·  Whole-Body Irradiation (1)

Sponsors

Case Comprehensive Cancer Center (1)  ·  Children's Oncology Group (1)  ·  Fred Hutchinson Cancer Center (1)  ·  PharmaEssentia (1)

Countries

United States (4)  ·  Canada (2)  ·  Australia (1)  ·  China (1)  ·  Denmark (1)  ·  Germany (1)  ·  Hong Kong (1)  ·  Japan (1)  ·  Jordan (1)  ·  New Zealand (1)  ·  Puerto Rico (1)  ·  Saudi Arabia (1)  ·  Singapore (1)  ·  South Korea (1)  ·  Taiwan (1)

Top investigators

Betty Hamilton, MD (1)  ·  Brenda Sandmaier (1)  ·  Jason N Berman (1)  ·  Toshiaki Sato, MD/PhD (1)

Results publications

PMID 31248843, PMID 32499241, PMID 37352262, PMID 41124669

NIH funding

P01CA018029 (1), P30CA015704 (1), U10CA180886 (1)